封闭群

方法：取封闭群健康wistar大鼠作为供受体。

Methods : Outbred wistar male rats were used as blood and pancreas donor and diabetic recipients .

应用微卫星标记对三个昆明小鼠封闭群的遗传学研究

Microsatellite Analysis in 3 Kunming Mice Outbred Colonies

昆明（KM）小鼠封闭群部分生物学特性变异的探讨

Studies on variation of biological character about colsed colony KM mice

建立供体封闭群SD大鼠到受体近交系Wistar大鼠的同种异体原位肝脏移植模型。

Establishing orthotopic liver transplantation model using SD rats to Wistar rats .

SPF级封闭群SD大鼠血清生化值及凝血酶原时间值的测定

Serum Biochemical and Prothrombin Reference Rangers of SPF Closed Colony SD Rat

用荷兰产ISP半自动生化分析仪对不同性别四个年龄段的Wistar封闭群大鼠的14项血液生化值进行了测定。

Hematological and biochemical values of male and female Wistar rats at different ages were determined .

目的：比较河南医科大学实验动物中心昆明（KM）小鼠与河北医科大学KM小鼠两个封闭群部分生物学特性的差异。

Aim : To compare biological character of two closed colony KM mice from Henan Medical University and Hebei Medical University .

方法：选用吉林大学实验动物部提供的普通级封闭群KM小白鼠（合格证号：10-1023），体重15~17g，雌雄各半。饲以本校动物室提供的饲料，饮用自来水。

Method : Choose common KM mice of animal basement in JILIN university , weigh : 15-17g , sex in half .

封闭群东方田鼠染色体制备中ConA的应用技术研究

Application of Preparation Chromosome with ConA in Closed Breeding Microtus fortis

AMS（Wistar）封闭群大鼠的繁殖性能及季节对其影响的研究

Investigation on Reproductive Performance of AMS ( Wistar ) Closed Colony Rat and Seasonal Effects on It

封闭群ICR小鼠肠道寄生虫感染情况调查

Survey on Intestinal Parasitic Infection in ICR Mice in Xi'an

方法56只成年健康Wistar封闭群大鼠，供受体各28只，采用受体肝分步切除的三袖套法行大鼠原位肝移植术。

Methods There are 56 Wistar rats included 28 of receptors and 28 of donators . Tri-cuff technique orthotopic liver transplantation was performed .

方法：选用近交系F344/N和封闭群Wistar/A大鼠建立同种异基因小肠移植模型36例，应用免疫组化检测bcl-2及bax在移植肠组织中的表达。

Methodes : Using inbred F344 / N and Wistar / A rats allogene small intestinal transplantation model , the expression of bcl-2 and bax were detected with immunohistochemistry .

目的构建封闭群动物SD大鼠骨组织工程模型，研究含孔磷酸钙陶瓷为支架复合自体成骨细胞的异位骨形成和极量骨缺损修复能力。

Objective To investigate the ability of heterotopic osteogenesis and reconstruction of critical size calvarial defect , a bone tissue engineering Sprague Dawley rat model with autogenous osteoblasts loading on porous calcium phosphate ceramic was established .

结论：封闭群SD大鼠肾被膜下和肠系膜内环境有利于同种异体牙胚的生长，可为组织工程化牙齿的体内构建提供新的发育环境。

Conclusion : The environment under the renal capsule or in the mesenteries of closed colony rat is favorable for the growth of allogeneic rTGs and can be used as a new alternative for bioengineered tooth development in vivo .

被检16个位点中，多态性位点占43.75%（7/16），群体平均杂合度为0.1875，二者明显高于国际公认的NIH封闭群小鼠。

Of the 16 loci examined 43 . 25 % ( 7 / 16 ) is polymorphic , the average heterozygosity is 0 . 1875 , and both the figures are higher than those generally recognized in NIH mice of closed colony .

方法将糖尿病地鼠作为实验组，昆明种封闭群正常小白鼠作为对照组，在注射胰岛素0、5、30、60及120min五个不同时间点分别测定每只小鼠的对应时间的血糖值。

Methods The Chinese diabetic mice were selected as the experiment group , Kunming mice as the control group . Blood sugar was measured at 0,5,30,60 and , 120 minutes after insulin injection .

长春封闭群日本大耳白兔生长发育的研究

Growth Characters and Development of Changchun Closed Colony Japanese White Rabbits

布氏田鼠封闭群建立及繁殖特性研究

Establishment of cleaning grade closed colony of Microtus brandti and reproductive traits analysis

封闭群草原兔尾鼠正常血液生化指标的测定

Determination of Normal Blood Biochemical Parameters of a Closed Colony of Lagurus lagurus

普通级长爪沙鼠封闭群的建立

Establishment of the Conventional Grade Mongolian Gerbil Closed Colony

无毛小鼠封闭群与昆明小鼠生长特性比较

The comparative study of growth about closed colony hairless mice and KM mice

方法：建立封闭群大鼠角膜移植模型，用裂隙灯显微镜记录及比较各组角膜排斥反应发生时间；

METHODS : The corneal transplantation model on the closed colony rats was established .

选用封闭群4周龄的清洁级雌性非肥胖糖尿病小鼠85只。

Eighty-five clean-grade NOD female mice were kept in an isolated system , 4 weeks age .

年龄和性别因素对封闭群草原兔尾鼠正常血液生化指标的影响

The Influences of Ages and Sexes on Normal Blood Biochemical Parameters in the Lagurus lagurus Closed Colony

结论：长爪沙鼠虽为北方物种，但经严格饲养在华南地区可以培育出合乎标准的封闭群，并可用于多方面的研究实验。

Conclusion The successful establishment of a standard conventional Mongolian gerbil closed colony will benefit the research in many aspects .

大耳白兔中国兽药监察所封闭群的建立

The Establishment of Closed Colony of the China Control Institute of Veterinary Drug ( CIVD ) from Japanese White Rabbit

结果提示，广西巴马小型猪具有一定的遗传稳定性，已成为一个稳定的遗传群体，符合封闭群动物的遗传特征。

The results suggested that Bama Miniature pig is a genetically stability breed and satisfies the genetic standard of closed colony animal .

最终筛选出的10个微卫星位点可做为封闭群遗传质量控制标记库的候选位点。

We concluded that these ten microsatellite locus may be as the candidate of the genetic quality control markers in closed rabbit colonies .

引入了一系列新的概念：如稳定群、稳定群的级、绝对封闭群等。

A series of new ideas , such as steady clusters , levels of steady clusters , absolutely closed steady clusters are introduced .