局部缺血

在肿瘤、细胞凋亡、局部缺血、炎症、伤口愈合及疼痛等病理状态下，P受体的内源性配体亦发挥着重要的作用。

In the pathologic state of tumour , apoptosis , ischemia , inflammation , wound healing , pain , etc.

可控性大鼠急性脑局部缺血模型的建立及CT灌注成像与病理学评价

Modeling of a controllable acute regional cerebral ischemia in rats and evaluation with CT perfusion imaging and histopathology

这些患者更容易发生围手术期心肌的局部缺血、心律失常和心血管的不稳定

Such patients are more prone to perioperative ischaemia , arrhythmias , and cardiovascular lability .

脑肿瘤患者术前由于肿瘤压迫使脑血流循环改变，局部缺血缺氧，导致NOS活性增强，NO产生增加。

These changes result in ischemia and hypoxia in local region that increase activity of NOS , so NO increases .

兔脑局部缺血后脑组织ATP酶活性及SEP、TCD改变

Changes of ATPase activity , somatosensory evoked potentials and transcranial Doppler sonographs after middle cerebral artery occlusion in rabbits

目的：探讨周围神经局部缺血后相关神经元胞体乙酰胆碱酯酶（acetylcholineesterase，AchE）含量的变化。

Objective : To investigate the changes of acetylcholine esterase ( AchE ) in relevant pericaryon after peripheral nerve ischemia .

研究表明，LA对糖尿病、白内障、局部缺血再灌注和放射性损伤等自由基性疾病具有预防和治疗作用。

It has been shown that LA can be used in the prevention and therapy of diabetes , cataract , ischemia , hypoxia / reoxygenation , irradiation injury , etc.

结果局部缺血区域神经元DNA损伤于再灌注12h开始出现，24h最为严重，72h开始减轻。

Results Neuronal DNA damage appeared in ischemic tissue at 12 hours of reperfusion , peaked at 24 h , started to decrease at 72 h.

方法通过阻断血运前将PNS经直接通道注入并保留于肝脏组织的方法并提取肝脏局部缺血再灌注模型大鼠肝细胞线粒体，测定线粒体成分的SOD总活力、MDA含量；

[ Methods ] To infuse and reserve PNS to rat liver though direct channel before blood blocked and then to gain rat mitochondria with ischemia reperfusion .

MSCs还能释放一些生物活性物质抑制局部缺血引起的凋亡，抑制疤痕组织的形成，刺激血管生成，创造良好的再生微环境。

Moreover , MSCs secrete bioactive factors that inhibit ischemia-caused apoptosis , prevent the formation of scar tissue , stimulate angiogenesis , and establish a favourable regenerative microenvironment .

直接夹闭腹主动脉造成脊髓局部缺血后，刺激腓神经诱发的同侧脊髓背表面电位，按P、N、A的顺序消失，以P波变化为最显著；

Following segmental ischemia in the spinal cord produced by direct occlusion of the abdominal aorta , the cord dorsum potentials disappeared in the sequence of waves P , N , and A , with maximum change in the amplitude of P wavee ;

目的：探讨脑动态CT峰值时间（TTP）灌注成像对短暂性脑局部缺血发作（TIA）的诊断价值。

Purpose : To evaluate the diagnostic value of time - to - peak perfusion mapping using dynamic CT with a personal computer for transient ischemic attack ( TIA ) .

于左侧第四肋间打开胸腔，剪开心包，在左冠状动脉前降支（LAD）根部穿一细丝线，结扎LAD使心脏局部缺血5min，之后松开结扎线再灌注30min。

The anaesthetized rats were subjected to 5 min of left descending coronary artery ( LAD ) occlusion followed by 30 min of reperfusion .

虽有证据表明高浓度UA对血管内膜、内皮细胞、局部缺血缺氧组织等有损害作用，但确切的机制尚未十分明了。

There are few evidence that high UA could injure intima of vessel , endothelial cell and ischemia or hypoxia constitution , but the certain mechanism is not distinct .

然而，由于移植区域恶劣环境（如：局部缺血、氧化应激、炎症反应等）的作用以及一次性植入大量细胞产生细胞接触抑制而导致MSCs大量的凋亡或死亡，从而降低了细胞治疗效能。

However , bad transplanted environment ( such as ischemia , oxidative stress , inflammatory reaction ) and contact inhibition , which cause abundant death or apoptosis of MSCs , are unfavorable for application of cell therapy .

结论无心梗患者运动诱发心电图ST段抬高是冠脉痉挛或冠脉严重狭窄所致心肌局部缺血的标志，且对预测冠状动脉病变部位有一定意义。

Conclusion It is a sign of myocardial ischemia resulting from spasm or severe stenosis of proximal coronary artery that exercise-induced ST segment elevation in patients without myocardial infarction . The leads of ST segment elevation are well correlated with the ischemia-related artery .

新型抗缺血药物治疗急性冠状动脉综合征的评价：雷诺嗪用于减少非ST段抬高型急性冠状动脉综合征局部缺血的代谢效能（MERLIN）-TIMI36试验的试验设计与原理

Evaluation of a novel anti-ischemic agent in acute coronary syndromes : Design and rationale for the Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST elevation acute coronary syndromes ( MERLIN ) - TIMI 36 trial

经皮冠状动脉成形术（PTCA）术后局部缺血并发症包括：急性冠状动脉闭塞，发生率2%~10%，病人的死亡率随之增加。

The ischemic complications of percutaneous transluminal coronary angioplasty ( PTCA ) include abrupt closure , which occurs in 2 % to 10 % of patients , and is associated with increased morbidity and mortality .

结论：局部缺血预处理后，缺血和非缺血区两处心肌的内反应呈一致性；缺血预处理对心肌的保护作用可能与HSP70的合成增多有关。

CONCLUSION : The heart might be activated as a whole ' in some way after regional ischemic preconditioning ( PC ), and the protection effect of PC might be related to the increased synthesis of HSP 70 .

IAS痉挛使肛管静息压增高，压迫血管导致局部缺血，致使肛裂形成和慢性化。侧方内括约肌切开术和扩肛术是肛裂手术治疗的最常用术式，然而术后有可能出现永久性大便失禁。

IAS spasm makes the resting anal pressure rise and compresses the blood vessel , while the local ischemia makes anal fissure occur and become chronic . Lateral internal sphincterotomy and anal dilatation are common used methods for anal fissure , but both have the risk of permanent incontinence .

方法5只新西兰大白兔制备成肝脏局部缺血模型。

Methods Partial hepatic ischemia model of 5 rabbits were set up .

坐骨神经局部缺血后相关神经元胞体乙酰胆碱酯酶变化的定量分析

Quantitative analysis of AchE change in relevant pericaryon after sciatic nerve ischemia

大鼠坐骨神经局部缺血对其轴浆运输的影响

Effects of sciatic nerve ischemia on axoplasmic transport in rat

山海丹对犬局部缺血区静脉血血液流变学特性的改善作用

Effects of Shan Hai Dan on blood rheology in experimental canine myocardial ischemia

体外实验显示甲状腺原氨酸或3-碘化甲状腺原氨酸对于局部缺血无神经保护作用。

In vitro studies showed no neuroprotective effect of thyronamine or3-iodothyronamine against ischemia .

犬心脏局部缺血和再灌注时血液动力学变化

Hemodynamic Changes During Myocardial Ischemia and Reperfusion on Dogs

缝合造成组织局部缺血坏死，创面非但不愈合反而扩大。

Suturing causes local ischemia and necrosis , enlarging and worsening the wound .

一种新的鼠大脑局部缺血模型

A new focal cerebral ischemia model of rats

大鼠坐骨神经局部缺血后其神经元胞体超微结构的病理变化

Pathological changes in the ultrastructure of neuronal soma after sciatic nerve ischemia in rat

鼠脑局部缺血再灌注的形态学与细胞凋亡的研究

A study of morphological change of ischemia reperfusion and cell apoptosis in rat brain