巴比妥类

GC/MSD分析生物样品中的巴比妥类药物

Analysis of Barbiturates in Biological Specimen by GC / MSD

逐步组合法用于选取13种巴比妥类药物的最佳层析系统

Selection of optimal TLC system combination for chromatographic separation of 13 barbiturates by stepwise combination method

在PTC条件下合成了多亚甲基桥连的双巴比妥类化合物1～3，并通过了元素分析、IR及1HNMR予以鉴定。

In the present article , three new compounds 1 ￣ 3 of bis barbital bridged with polymethylene groups have been synthesized and characterized by elemental analyses , IR , 1H NMR spectra .

在中性提取条件下，巴比妥类药物GC－FID的最低检出浓度为2～5μg／ml，在优化的提取条件下，可降至0.3～0.5μg／ml。

Under neutral extraction conditions , the lowest detection limits of barbitals were in the range of 2 ~ 5 μ g / ml , in optimized conditions , they were reduced to 0.3 ~ 0.5 μ g / ml.

沙利度胺（酞胺哌啶酮thalidomide）属于非巴比妥类药物，最早作为镇静止吐药物用于临床，后发现具有严重的致畸作用而被禁用。

Thalidomide , a non-barbiturate drug , is used as a sedative antiemetic drug , and shows a significant teratogenic effect , has once been banned .

结果检测血液中五种巴比妥类药物的最小检出限（LOD）均为10ng/mL，线性范围在0.02￣10μg/mL内良好，方法的回收率70%￣87%。

Results The limits of detection ( LOD ) were 10ng / mL for all the 5 barbiturate drugs , the calibration range 0.02 ( 10 μ g / mL ), the recovery rate 70 ( 87 % ) .

LC-MS/MS同时分析血液中五种巴比妥类药物

Determination of Five Barbiturate Drugs in Blood by LC-MS / MSB

巴比妥类及其混合药物鉴定的谱学研究

Spectra Research on the Identification of Mixture Medicine of Barbitals

GC&FTIR标准谱库的建立及其在巴比妥类药物筛选分析中的应用

The Creation of a Standard Library of Spectra Using GC-FTIR and Its

目的建立血液中巴比妥类药物液相色谱-串联质谱检测方法。

Objective To establish a method for determination of barbiturate drugs in blood .

电位双点滴定法测定巴比妥类药物

Determination of Barbitals by Potentiometric Double-Point Titration

而且，多种巴比妥类专利药物的专利在2006年到期，加剧了竞争。

Also , several blockbuster brand-name drugs lost their patent exclusivity in2006 , generating competition .

当测定浓度超过1毫克／100毫升的巴比妥类药物时，必须用更多的双硫腙。

More diphenylthiocarbazone should be used to estimate barbiturate concentrations above 1 mg / dl .

生物试样中巴比妥类药物固相提取柱上衍生化GC/MS分析

Determination of barbiturates from biological tissues by solid-phase extraction , on-column derivatization GC / MS analysis

巴比妥类麻醉下低温对大鼠自然杀伤细胞活性及肿瘤转移易感性的影响

Effect of hypothermia under barbiturate anesthesia on natural killer cell activity and lung metastasis in rats

固相萃取-紫外差示导数光谱法测定血肝尿中巴比妥类药物

Determination of Barbiturates in Blood , Liver and Urine by Solid-phase Extraction and UV Differential Derivative Spectrophotometry

文章针对应用该技术研究的低温、过度换气和巴比妥类药物对脑组织能量代谢的影响进行综述。

The article reviews the effects of hypothermia , hyperventilation and barbiturates on brain energy metabolism study with microdialysis techniques .

目的探讨巴比妥类药物麻醉下低温对大鼠自然杀伤细胞活性和肿瘤转移的影响及可能机制。

Objective To explore the effect of hypothermia on the natural killer cell activity in blood and host susceptibility to metastasis and the possible mechanism .

本文提出在水溶液中，用酸碱电位双点滴定法测定巴比妥类药物的含量，该方法测定巴比妥类药物简便快速。

A method is proposed for the determination of barbitalums by acid-base titration , using double-point potentiometric method in the media of water solution with the silver se - , lective electrode .

戊巴比妥钠对中枢神经系统产生抑制作用，并显示戊巴比妥类特有的镇静催眠作用。

Nembutal Sodium exerts a depressant action on the CNS and shares the sedative-hypnotic actions typical of the barbiturates .