抗原提呈
- 网络Antigen presentation;antigen present;antigen presenting;APC
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B淋巴细胞膜表面IgM在抗原提呈中的作用
Role of B cell surface IgM in antigen presentation
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IL-4可促使活化的B细胞分裂增殖,并增强B细胞抗原提呈的能力。
IL-4 can stimulate the differentiation of B cell and enhance its ability of antigen presentation .
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适应性免疫应答的启动需要DC的抗原提呈。
Adaptive immune response is conditional upon angtigen presentation of DC .
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维生素C、皮质醇对正常人外周血单核细胞抗原提呈功能的影响
Effects of ascorbic acid and cortisol on the antigen-presenting function ( APF ) of normal human monocytes
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树突状细胞(DC)是具有最强抗原提呈能力的专职性抗原提呈细胞。
Dendritic cell ( DC ) is the most powerful professional antigen-presenting cell .
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树突状细胞(Dendriticcells,DC)在体内抗原提呈方面起重要作用。
Dendritic cells ( DC ) play important roles in the process of antigen presenting .
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结论作为抗原提呈细胞的DC和具有特异性抗肿瘤免疫活性的T淋巴细胞能较全面客观地反映膀胱移行细胞癌宿主局部抗肿瘤免疫状态,两者是判断膀胱移行细胞癌预后的可靠性指标。
Conclusion Both the dendritic cells and T lymphocytes are trustworthy indexes to determine the prognosis of transitional cell bladder cancer .
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另外,IFN-γ可诱导巨噬细胞、T细胞、B细胞等细胞MHC-Ⅰ和MHC-Ⅱ类分子表达,从而提高抗原提呈能力;
Increase the expression of MHC class ⅰ and MHC class ⅱ molecules on macrophages 、 T cells and B cells and improve their antigen-presenting ability ;
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背景与目的:树突细胞(Dendriticcell,DC)是重要的抗原提呈细胞,参与抗肿瘤免疫。
BACKGROUND & OBJECTIVE : Dendritic cells are the important antigen presenting cell , and take part in the anti tumor immunoreaction .
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结论这一结果可能为应用外源蛋白负载(loading)抗原提呈细胞(APC)提供新的途径。
Conclusion These results may provide a new approach for loading exogenous proteins to antigen presenting cells .
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目的:树突状细胞(Dendriticcells,DCs)是体内功能最强大的专职抗原提呈细胞,能激发机体初次特异性免疫反应。
Objective : Dendritic cells are the most potential professional antigen presenting cells , which can innate immune response in body .
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IL-2基因修饰增强树突状细胞抗原提呈功能及其机制
Enhancement of antigen presenting function of dendritic cells by IL-2 gene modification and its mechanism
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免疫应答的产生首先由抗原提呈细胞(antigen-presentingcell,APC)摄取抗原,经其加工、处理后将信息传递给淋巴细胞,引发一系列特异性免疫应答。
The first step of immune response is antigen-presenting cell ( APC ) intape antigens .
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树突状细胞(Dendriticcells,DC)是功能最为强大的专职抗原提呈细胞,能够激活初始免疫反应。
Dendritic cells ( DCs ) are the most effective or ' professional ' of the antigen-presenting cells ( APC ) that initiate primary immune responses .
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动态观察创伤对AM、IM吞噬、抗原提呈以及分泌功能的影响;
Changes of the phagocytosis , angtigen presentation and secretion of AM and EM after trauma were observed dynamically ;
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目前认为RA的发生是由抗原提呈细胞(APC)对自身抗原的异常提呈所引起的。
It is believed that RA is caused by the presentation of self antigen by APC .
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因此对HPV感染的治疗从提高HPV抗原提呈效率,加强局部免疫应答着手,达到对病毒感染细胞的有效清除,将最大限度地降低复发率和肿瘤形成。
To improve antigen-presenting condition in HPV-related lesions and enhance immune response will effectively eradicate virus-infected cells .
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如何恢复或加强DC的抗原提呈能力,充分发挥机体免疫功能已成为治疗CHB急需解决的问题之一。
One of the exactly questions to treat CHB is how to enhance the antigen presentation function of DC .
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在许多抗原提呈细胞(Antigenpresentingcells,APCs)上已发现大量的甘露糖受体,这提示甘露糖可能参与抗原的提呈。
Many antigen presenting cells contained mannose receptor , so , the mannose might participate in the process of antigen presenting .
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脾内途径的肝脏靶向性基因治疗中Kupffer细胞的抗原提呈作用
The effect on the antigen-presenting function of Kupffer cells by liver-targeting gene therapy
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然而DNA疫苗这样的亲水性大分子药物是无法穿透皮肤角质层的屏障,并且皮肤内的酶系会对DNA疫苗产生降解作用,而使抗原提呈细胞无法捕获DNA疫苗。
But hydrophilia macromolecule drug like DNA vaccine can not penetrate the keratoderma and enzyme system in skin will degrade DNA vaccine so that antigen presenting cell can not catch DNA vaccine .
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另一方面抗原提呈功能下降,又导致T、B细胞反应性下降,免疫功能受到明显抑制,往往导致严重感染,从而这两方面共同造成了严重创伤的高死亡率。
On the other hand the antigen presenting ability drops , which decreases the responses of T and B cells . So the immune function is obviously suppressed , which often results in infection .
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而且,MSC是弱的抗原提呈细胞,不表达MHCⅡ类分子或共刺激分子。
Moreover , MSC are poor antigen-presenting cells and do not express MHC class II or co-stimulatory molecules .
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树突状细胞(Dendriticcells,DCs)是存在于外周血和淋巴组织中的专职抗原提呈细胞,参与维持免疫耐受和调节T细胞介导的免疫反应。
Dendritic cells ( DCs ) is the professional antigen presenting cell in the peripheral blood and lymphoid tissue , involved in the maintenance of T-cell-mediated immune response .
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结论慢性粒细胞白血病细胞和K562细胞在细胞因子的诱导下,可分化为具有DC形态和功能的特异性抗原提呈细胞。
Conclusion DC driven in vitro from cells of CML and K562 can be differentiated into specific antigen presentation cells which have DC morphology and function .
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GM-CSF诱导红白血病细胞向树突状细胞分化及其抗原提呈功能的研究
The dendritic cell differentiation and antigen presenting function of the erythroleukemia cells induced by GM CSF
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用组合肽库技术分析HLA-B27的抗原提呈模式
Analysis of Antigen Motifs Presented by HLA-B27 Using Combinatorial Peptide Libraries
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背景树突状细胞(Dendriticcell,DC)属于起源干细胞的白细胞范畴,是初始免疫反应中最重要的抗原提呈细胞,特异性激活T天然细胞。
Background : Dendritic cells ( DCs ) are the most potent antigen - presenting cells that belong to in WBC initiated from stem cells , can activate native T cell .
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B细胞有作为专业抗原提呈细胞递呈抗原,促进T细胞活化,维持记忆性T细胞产生二度免疫应答及分化为浆细胞产生抗体的作用。
B cells are professional antigen presenting cells . B cells promote the activation of T cells , maintain the secondary immune responses of the memory T cells and can become plasma cells to secrete antibodies .
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目的研究体外小鼠骨髓树突状细胞对2种不同大小beadOVA复合物(0.04μmbead和1.0μmbead)的摄取及classⅠ途径抗原提呈能力。
Objective To study the uptake and class ⅰ pathway presentation of bead OVA with different sizes by IL 3 activated mouse bone marrow dendritic cells .