槐角

黑槐角总黄酮含量高于白槐角。

The content of total flavonoids in black Fructus Sophorae is higher than it in white Fructus Sophorae . 6 .

将采集的不同产地、不同时期的槐角样品按照2005版中国药典附录检测方法进行灰分、浸出物等测定。

To determine the ash and extract content of Fructus Sophorae samples from different places and different periods according to Chinese Pharmacopoeia . 3 .

采用HPLC法对槐角不同部位中槐角苷含量进行比较分析。

To determine the content of sophoricoside from different parts of the Fructus Sophorae by HPLC . 5 .

槐角苷及染料木素对成骨细胞生物学特性的影响

Effects of sophoricoside and genistein on biological characteristics of osteoblasts

槐角中的抗癌活性成分

The Anticancer Activity in vitro of Constituents from Fruits of Sophora japonica

槐角提取物在小鼠体内显示有弱雌激素样作用。

The Fructus Sophorae extracts have weak estrogen-like effect .

笔者建议本法可用于槐角丸的质量控制。

The proposed method can be used to control the quality of Huaijiao Wan .

槐角总黄酮对高脂血症大鼠降血脂及抗氧化能力的实验研究

Study of total flavonoid from fructus sophorae on lipid-lowering in hyperlipidemic rats and its antioxidant capacity

目的：观察槐角对D-半乳糖致衰小鼠血清和心肌的抗氧化作用。

Objective : To investigate the antioxidation in serum and myocardium of D-galactose-induced mice aging model with Huaijiao .

结论槐角颗粒与原丸剂型一样具有明显的止血、凝血及镇痛、抗炎、抗菌等药理作用。

Conclusion Huaijiao granule has obvious effect on bleeding and clotting time , analgesic , anti-inflammatory and antimicrobial .

目的：建立测定槐角丸中游离染料木素、总染料木素和黄芩苷的反相高效液相色谱法，并用该方法测定了3种不同厂家的槐角丸。

Objective : To establish a HPLC method for determining of free genistein , total genistein and baicalin in Huaijiao pills .

本文主要介绍了槐角丸在成分分析，药理作用，临床应用等方面的最新研究进展。

This paper reviewed the advanced study on the Huaijiao pills in aspects of component analysis , pharmacological acdon , clinical application and so on .

为了进一步对槐角的质量进行控制及临床用药和新药开发奠定物质基础，本试验对槐角苷进行了含量测定研究。

Studied the contents , Sophoricoside of Sophora fruit , in order to control quality of Sophora fruit and development of new medicine and clinical purpose .

槐角提取物能使小鼠卵巢增重、子宫增重、子宫内膜增厚、阴道开口时间提前和阴道开口率增加。

Uterine weight and ovarian weight increased by the the Fructus Sophorae extracts . The endometrium thickened . The vaginal opening rate of the immature female mice was also advanced .

渭南蒲城组、咸阳旬邑组提取物雌激素样作用表现明显，两提取物中槐角苷含量较高，表明槐角提取物的雌激素样作用主要源于其所含的异黄酮类化合物。

The estrogen-like effect of extract in Pucheng of Weinan and Xunyi of Xianyang is obvious . The two extracts contain more sophoricoside . We can conclude that estrogen-like effects of Fructus Sophorae extract mainly due to the isoflavones .

结论：神健胶囊各剂量组均能改善D半乳糖致衰小鼠的学习记忆功能，其机制可能与降低脑组织中脂质过氧化物的含量有关。槐角对半乳糖致衰小鼠血清及心肌抗氧化作用的研究

CONCLUSION : Shenjian capsule could improve the ability of learning and memory through reducing the MDA level in brain of aging mice . The study of the antioxidant effect in serum and myocardium of D-galactose-induced senile mice with different dose Huaijiao

染料木素，是一种大豆异黄酮类化合物，同时还是酪氨酸激酶抑制剂，具有雌激素样作用，广泛存在于金雀花、皂荚、槐角等豆科药用植物中，在大豆胚轴中含量也较为丰富。

Genistein is a kind of soy isoflavones , and also a kind of tyrosine kinase inhibitors , which widespreads in legumes such as broom , acacia , huaijiao and other medicinal plants and whose content is rich in soybean hypocotyl .

不同来源的槐角样品中总黄酮和槐角苷的含量有一定差异，这可能与日照时间、温度、海拔和干旱等因素有关。

We find that the content of total flavonoids in Fructus Sophorae from different sources has some differences , so is the content of sophoricoside . This may be related to the duration of sunshine , temperature , altitude and drought . 4 .

采用现代新型提取方法&超声提取法，从槐角中提取了抗癌活性成分染料木素。

The thesis , consisting of four chapters , presents the author 's scientific achievements from the following three aspects : 1 . With the application of a modern extraction method - ultrasonic extraction , Genistein , the anticancer activated composition , is obtained from Huaijiao .