水通道

水通道蛋白（Aquaporin，AQP）是一组具有同源性的内在膜蛋白家族成员，是水跨膜转运的主要分子基础。

Aquaporin ( AQP ) are a family of hydrophobic intrinsic membrane proteins that efficiently and selectively transport water . Aquaporin is the main molecular basis of water transmembrane transport .

目的：探讨星形胶质细胞形态学观察在高通量药物筛选水通道蛋白4（AQP4）抑制剂中的应用，为脑水肿和其他水转运障碍疾病的治疗提供理论依据。

Aim : To explore the method for high throughput drug screening searching for Aquaporin 4 ( AQP4 ) inhibitor and develop a new therapeutic approach to treat brain edema .

简并PCR检测细菌水通道蛋白基因的研究

A study of bacterial aquaporins with degenerate PCR

充血性心力衰竭时肾脏水通道蛋白mRNA表达的改变及意义

Expression of channel protein mRNA in kidney of congestive heart failure and its significance

脂多糖&烟雾诱导慢性支气管炎大鼠模型水通道蛋白5表达与肿瘤坏死因子α、白介素13、白三烯B4的变化

Expression of Aquaporin 5 and Changes of Tumor Necrosis Factor α, Interleukin 13 , Leukotriene B_4 in Lipopolysaccharide-Cigarette Smoking Inducible Chronic Bronchitis Rat Model

水通道蛋白4与视神经脊髓炎的关系基于OPENGL的蛋白质相互作用可视化研究

Relationship of Aquaporin-4 and Neuromyelitis Optica ; Visualizing Protein-Protein Interaction Based on OpenGL

LPS对鼠肺微血管内皮细胞水通道蛋白-1表达及其功能的影响

Effects of lipopolysaccharide on aquaporin-1 expression and function in rat lung microvessel endothelial cells

肝功能衰竭大鼠脑水通道蛋白-4表达与MRDWI的相关性研究

A Correlative Study between the Expression of Aquaporin-4 and Molecular Mechanism of MR DWI after the Hepatic Failure in Rats

ELISA法检测心力衰竭模型大鼠尿液水通道蛋白-2的变化及意义

Changes and significance of aquaporin-2 water channel protein in urinary concentration detected by ELISA in a rat model of congestive heart failure

去铁胺干预对大鼠ICH后水通道蛋白4表达变化的影响

Effect of Deferoxamine on Aquaporin-4 Expression in a Rat Model of Intracerebral Haemorrhage

抑制水通道蛋白1对Hep-2细胞增殖和凋亡的影响

Effect of inhibiting aquaporin-1 on proliferation and apoptosis of the Hep-2 cell

siRNA沉默水通道蛋白4治疗创伤性脑水肿的实验研究

An experimental study of siRNA targeting aquaporin 4 treatment on cerebral edema following traumatic brain injury

目前从哺乳动物组织中已鉴定出至少五种水通道蛋白，统称为水蛋白（aquaporin，AQP），均属于主体内在蛋白（MIP）家族的成员。

AQPs the members of major intrinsic protein ( MIP ) family .

胃泌素对结肠癌细胞株HT-29水通道蛋白4表达的影响

Effect of gastrin on aquaporin 4 expression in human colon cancer HT-29 cell line

大鼠脊髓损伤后脊髓水肿与水通道蛋白4（AQP-4）表达变化的研究

The Expression Changes of AQP-4 after Spinal Cord Injury of Rat

异丙酚预处理对HK-2细胞缺氧/复氧损伤后水通道蛋白1表达的影响

Effects of Propofol Pretreatment on the AQP-1 Expression after HK-2 Cells Injured by Anoxia-reoxygenation

目的了解急性脑出血后灶周脑组织水通道蛋白-4（AQP-4）的表达。

Objective To investigate the expression of AQP-4 after brain hemorrhage in human .

而且，我们发现，在利妥昔单抗治疗期间，水通道蛋白4抗体滴度与CD19细胞数相关。

Moreover , AQP4-Ab titres were found to correlate with CD19 cell counts during therapy with rituximab .

高原反应的脑病理与水通道蛋白-4（AQP4）的相关性实验研究

Study of aquaporin protein 4 with cerebral pathology and pathogenesis of high altitude response

水通道蛋白1（AQP1）在人类胎盘胎膜中的分布及表达

Expression and Distribution of Aquaporin 1 in Human Placentas and Fetal Membranes

水通道蛋白-2（aquaporin-2）在大鼠内耳的定位及其意义探讨

The Orientation and Its Significance of Aquaporin-2 in the Rat Inner Ear

大鼠创伤性脑水肿早期水通道蛋白AQP-4的表达及意义

Expression and Its Significance of the AQP-4 during Early Period Following Traumatic Brain Edema in Rats

脑损伤后12h、24h、48h给药，水通道蛋白4的表达和脑组织含水量差异无显著性（P>0.05）。

After 12 , 24 and 48 hours brain damage , the expression of aquaporin 4 and BWC had insignificant difference ( P > 0.05 ) .

水通道蛋白（aquaporin，AQP）是一族细胞膜上选择性高效转运水分子的特异孔道。

Aquaporins ( AQP ) are a family of hydrophobic intrinsic membrane proteins that efficiently and selectively transport water .

目的：观察水通道蛋白-4（AQP-4）对脑血吸虫病脑血管通透性的作用。

Objective : To investigate function of aquaporin-4 ( AQP-4 ) on vascular permeability in encephalopathy of schistosomiasis .

目的建立较为稳定的定量检测尿液水通道蛋白-2（AQP2）的酶联免疫吸附测定（ELISA）法。

Objective To develop an efficient and stable enzyme-linked immunosorbent assay ( ELISA ) for detecting urinary aquaporin-2 ( AQP2 ) water channel protein .

目的：检测水通道蛋白（AQP）-1,3在豚鼠耳蜗及内淋巴囊中的表达情况。

Objective : To detect the expression of Aquaporin-1,3 in the cochlea and endolymphatic sac of guinea pig .

各种导致脑水肿的因素可能最终通过影响水通道蛋白4（AQP4）而发挥作用。去铁胺，一种强有力的铁螯合剂，可减轻脑出血后的脑水肿形成。

Deferoxamine ( DFO ) - a potent iron chelator can relieve brain edema resulted from ICH and hemoglobin .

水通道蛋白（AQPs）是细胞膜上特异性转运水的孔道。

Aquaporins ( AQPs ) are membrane water channels , which selectively transport water across cell plasma membranes .

目的观察大鼠肺泡Ⅱ型上皮细胞水通道蛋白1（AQP1）的表达。

Objective To explore the expression of aquaporin-1 ( AQP1 ) in rat alveolar type ⅱ cells .