环境雌激素

环境雌激素对乳腺癌细胞株MCF-7凋亡作用的影响

Effects of Environmental Estrogens on Apoptosis in MCF-7 Cells

以VTGmRNA为生物标志物的环境雌激素筛选方法主要包括实时定量PCR、Northern杂交、原位杂交等。

Environmental estrogens screening methods , with VTG mRNA as a biomarker , include real-time quantitative PCR , Northern blot , in situ hybridization .

结论杀螟硫磷具有环境雌激素活性，其拟雌激素作用由ER介导而产生。

Conclusion Fenitrothion has environmental estrogenic activity which was mediated by ER .

雄性鱼类VTGmRNA是一种检测环境雌激素的新兴生物标志物。

VTG mRNA in male fish is a new kind of biomarker .

目的为建立环境雌激素基因重组酵母测评系统，构建雌激素效应元件（estrogenresponseelements，ERE）调控的酵母报告载体。

Objective To establish the recombinant yeast estrogen system ( RYES ), a reporter vector controlled by estro-gen response elements ( ERE ) in yeast was constructed .

根据单一环境雌激素检测结果，测定以上环境雌激素与E2混合后的活性变化。

Based on the results of single environmental estrogen activity , the activity of multiple environmental estrogens coexisting with E2 was determined .

目前已确定的环境雌激素主要包括：1.用于临床的人工合成类雌激素，如已烯雌酚（Diethylstilbestrol，DES）；

So far the determined EE comprises the following : 1 . The artificial composed estrogens used clinically , such as diethylstilbestrol ( DES );

环境雌激素DES对WISP-2基因的作用及WISP-2对BCL-2表达的影响

Effects of Environmental Estrogen Diethylstilbestrol on the Expression of WISP-2 Gene and Role of WISP-2 Gene on the Expression of BCL-2 Gene in Human Breast Cell Line MCF-7

己烯雌酚（DES）是一种人工合成的环境雌激素类物质，被广泛应用在临床和畜禽生产中，由于DES化学性质比较稳定，是医疗废水、工业废水中可检出的环境激素之一。

It is widely applied in clinical and the poultry production , because the DES chemical property is quite stable , it is one of environmental hormones that may pick out in the medical waste water and the industrial waste .

目的：探讨环境雌激素（EEs）对雄性胎鼠睾丸下降以及睾丸引带肌动蛋白表达的影响。

Objective To explore the effects of environmental estrogens ( EEs ) on testicular descent and expression of actin in gubernaculum testis ( GT ) of fetal male mice .

从结果可知，选取的环境雌激素均能诱导细胞增殖，E2引起雌激素效应的剂量最小，HCB诱导的雌激素效应最强，所有环境雌激素的剂量效应关系都符合抛物线形状。

The results showed the selected environmental estrogens induced cell proliferation . The active dose of E2 was the lowest and estrogen effect of HCB was the highest . The dose-effect relationships of all environmental estrogens accorded with the form of a parabola .

目的研究炔雌醇（EE2）对斑马鱼的卵黄蛋白原（VTG）及性腺发育的影响，并通过一系列生殖发育终点指标的研究选择有效筛选环境雌激素（EEs）的敏感指标。

Objective To study the effect of ethynylestradiol ( EE_2 ) on vitellogenin ( vtg ) and gonad development of zebrafish ; to select sensitive biomarkers for screening environmental estrogens using zebrafish .

结论：重组酵母测评系统检测环境雌激素的优化组合为：恒温培养箱中酵母扩增24～30h，受试物作用30h，Y-PER或液氮裂解酵母细胞。

Conclusion : The optimal experimental conditions for the recombinant yeast estrogen system in environmental estrogens detection were that the yeast cells were multiplied under non-vibrating from 24h to 30h , the exposure time of tested substances was 30h , and yeast cells were broken by liquid nitrogen or Y-PER .

塑料玩具中7种环境雌激素含量检测

Detection of 7 estrogens contents in 32 kinds of plastic toys

久效磷对金鱼的环境雌激素效应的研究

Research on the environmental estrogen activity of monocrotophos on goldfish

三氯杀螨醇对大型溞的毒性和环境雌激素效应

Reproduction toxicity and estrogenic effects of dicofol to Daphnia magna

环境雌激素对生殖和发育毒性的分子机理

Molecular mechanisms of environmental estrogens on reproductive and developmental toxicity

环境雌激素分子印迹材料制备及其样品前处理中的应用研究

Molecularly Imprinted Polymers of Environmental Estrogens and the Application in Sample Pretreatment

环境雌激素对人体和动物影响机制的研究进展

Review on mechanisms of action of environmental estrogen on human and animals

地表水和自来水中环境雌激素活性物质的检测

Determination of Environmental Estrogens in Surface Water and Tap Water

杀螟硫磷体外环境雌激素活性及机制研究

Study on environmental estrogenic activity of fenitrothion in vitro and its mechanism

羊肉中环境雌激素的气相色谱-质谱测定法

Determination of Environmental Estrogens in Mutton by Gas Chromatography-Mass Spectrometry

快速筛选环境雌激素酵母细胞的试验研究

The experimental verification for rapid screening of the yeast cell of environmental estrogen

目的建立环境雌激素的体外快速筛选方法。

Objective To develop a rapid screening method of environmental estrogen in vitro .

四种拟除虫菊酯类农药的环境雌激素活性研究

Determination of environmental estrogenic activity of four pyrethroid pesticides

气相色谱质谱法测定尿及河底泥中的环境雌激素

Determination of Environmental Estrogens in Urine and Bed Mud by Gas Chromatography-Mass Spectrometry

环境雌激素的作用机制与毒性检测

Mechanism and toxicology test of the environmental estrogens

重组酵母测评系统检测环境雌激素的影响因素探讨

Study on Influencing Factors of the recombinant yeast estrogen system in environmental estrogens detection

环境雌激素及其降解途径

Environmental Estrogens : Their Problems and Degradation Pathway

环境雌激素生物效应的受体途径研究

Receptor - dependent Biologic Effects of Environmental Estrogens