砒石

砒石对哮喘小鼠白三烯B4及5-脂氧合酶基因表达的影响

Effects of arsenolite on leukotriene B_4 and genic expression of 5-lipoxygenase in asthmatic mice

目的探讨5脂氧合酶激活蛋白（FLAP）基因表达、小鼠白三烯C4（LTC4）水平在小鼠哮喘发病中的作用，以及砒石对哮喘的治疗作用与FLAP基因表达及LTC4水平的关系。

Objective To investigate the role of the expression of 5-lipoxygenase-activating-protein ( FLAP ) and the leukotriene C_ 4 in ovalbumin-challenged asthmatic mice and to study the effect of arsenolite on the expression of FLAP and the leukotriene C_ 4 and the mechanism of arsenolite inhibiting asthma .

砒石对哮喘小鼠信号转导和转录激活因子6及嗜酸粒细胞趋化因子mRNA表达的影响

Effects of arsenolite on expressions of signal transducer and activator of transcription 6 and eotaxin ( mRNA ) in asthmatic mice

目的：探讨胞质型磷脂酶A2（cPLA2）mRNA表达、白三烯C4（TLC4）在哮喘发病中的作用及其相互关系，以及砒石对哮喘的治疗作用。

AIM : To study the effects of arsenolite on the leukotriene C_4 and the expression of cPLA_2 mRNA in ovalbumin challenged asthmatic mice .

砒石对哮喘小鼠气道壁厚度及c-myc与c-sis表达的影响

Effects of arsenolite on the airway thickness and the expressions of c-myc and c-sis in asthmatic mice

砒石对哮喘小鼠血浆8-Isoprostane的影响

Role of arsenolite on 8-isoprostane of asthmatic mice plasm

黄芪减少砒石对大鼠氧化性损伤作用机制研究

Decreasing Oxygen Radical Damage by Taking Astragalus and Arsenolite together in Rats

砒石对哮喘小鼠肺组织白三烯含量的影响

Effects of arsenolite on the leukotriene B_4 and the leukotriene C_4 in the lung of asthmatic mice

结论：哮喘小鼠机体存在氧化应激状态，砒石能够减轻其气道阻塞，降低气道高反应性，纠正氧化/抗氧化失衡。

Arsenolite could lighten airway obstruction , reduce airway high response and redress oxidant stress status in asthmatic mice .

黄芪在拮抗砒石致大鼠氧化性损害及其对肝脏毒性可能起到一定程度的作用。

Oral administration of astragalus membranccus and arsenolite together may decrease the oxygen radical damage and the liver injury induced by arsenolite in rats obviously .

[目的]探讨中药黄芪在减轻砒石致毒大鼠氧化性损伤及其对肝脏毒副作用的影响。

[ Objective ] To investigate the possible mechanisms of oral administration of astragalus in decreasing liver toxic action and the oxidative damage in rats injured by arsenolite .