缺血性脑水肿

结论：AQP-4是影响缺血性脑水肿的重要因素。

CONCLUSION : AQP 4 is the important factor which influences the ischemic cerebral edema .

目的研究缺血性脑水肿病理过程中血脑屏障内皮细胞及其细胞间粘附分子－1（Intercellularadhesionmolecule-1，ICAM-1）的表达与血脑屏障通透性的关系。

Objective To study the relationship of the changes of endothelium , the expression of intercellular adhesion molecule-1 ( ICAM-1 ) and the permeability of blood-brain barrier ( BBB ) during the pathologic course in ischemic cerebral edema .

结论：MRI可以作为缺血性脑水肿的早期诊断方法。

Conclusion : MRI am be recommended as a nearly diagnostic tool for the detection of cerebral ischemia edema .

目的用MRI影像学方法检测抗脑水肿药对急性脑梗死后缺血性脑水肿的治疗效果。

Objective To investigate the efficacy of drugs used to treat brain edema in a rat acute cerebral infarction model by MRI image analysis .

结论脑淋巴引流障碍能明显加重MCAO后缺血性脑水肿。

Conclusions Obstruction of cerebral lymphatic drainage may deteriorate ischemic brain edema after MCAO .

缺血性脑水肿的AQP-4表达与磁共振成像的相关性研究

Study on Correlation between AQP-4 Expression and MRI of the Ischemic Brain Edema

结果表明，侧脑室注射V2，V1/V2受体拮抗剂可显著减轻沙土鼠的缺血性脑水肿，用V1受体拮抗剂则无类似效应。

The result showed that intracerebroventricular injection ( ICV ) of V_2 and V_1 / V_2 receptor antagonist respectively decreased significantly the ischemic brain edema of gerbils , while V_1 receptor antagonist had no such effect .

本实验探讨了精氨酸加压素（AVP）对蒙古种沙土鼠急性缺血性脑水肿的作用及其机理。

The purpose of this experiment was to study the role of arginine vasopressin ( AW ) in acute cerebral ischemic edema in mongolian gerbils .

结论：外源性PACAP对缺血性脑水肿具有保护作用，该作用是由I型受体介导的。

Conclusion : Exogenous PACAP may act as a protective effect in brain edema induced by ischemia in rats , which is mediated by type ⅰ receptor .

其作用机理可能是通过cAMP、cGMP介导的AVP受体的作用，产生抑制脑细胞膜Na~+-K~+ATP酶活力的效应，从而促进缺血性脑水肿的形成。

And its mechanism might be the effect of AW on AW receptor mediated by cAMP , cGMP , and that in turn inhibited the Na + - K + ATPase activity of brain cell membrane , then exaggerated the formation of ischemic brain edema .

甘露醇治疗缺血性脑水肿的实验研究

Experiment research on therapeutic effects of mannitol in ischemic cerebral edema

重症缺血性脑水肿的颅内压监护及治疗

Intracranial pressure monitoring and treatment of severe ischemic brain edema

评价抑肽酶对缺血性脑水肿的抑制作用。

Evaluate the anti-action of Aprotinin in ischemic brain edema .

利多卡因和复方甘油对实验性缺血性脑水肿的作用比较

Comparison of effects of lidocaine and compound glycerin on experimental ischemic cerebral edema

水通道蛋白-4在早期缺血性脑水肿中的表达

AQP-4 expression at early stage of ischemic brain edema

缺血性脑水肿的发病机制及研究进展

The pathogenesis and research progresses of ischemic cerebral edema

甘露醇对缺血性脑水肿水通道蛋白4表达水平影响的研究

The Study of Mannitol 's Effect on Aquaporin-4 Expression of Ischemic Cerebral Edema

实验性不同时间缺血性脑水肿超微结构观察

Observation on pathology of various time ischemic cerebral edema

精氨酸加压素对沙土鼠急性缺血性脑水肿的作用

The Effect of Arginine Vasopressin ( AVP ) on Acute Ischemic Brain Edema in Gerbil

大鼠脑淋巴引流对缺血性脑水肿影响的作用研究

Experimental study of the effect of cerebral lymphatic drainage of rat on regional brain ischemia

水蛭肽对犬脑血流量及大鼠缺血性脑水肿的影响

The effect of hirudin injection on the brain blood flow of dog and brain edema of in mice

结果显示：缺血性脑水肿的颅内压变化及治疗效果有其特殊性，有效的降低颅内压、减轻脑水肿可提高治疗效果。

This result indicates that changes of the intracranial pressure is more special in the patients with severe ischemic brain edema .

结论水蛭肽注射液具有明显的防治缺血性脑水肿、改善脑循环的作用。

Conclusion Hirudin injection have the effect of prevention and cure on the brain edema by cerebral ischemia and reform the cerebrovascular circulation .

而缺血性脑水肿是该病发生发展的重要病理过程，虽然机制仍不完全明确，但可以肯定的是水转运障碍是水肿发生的基础。

Although the detail has not been definite , we can deduce that the handicap of water transport is the key of brain edema .

选择性地降低麻醉犬的椎动脉阻力；还能通过增加缺血区脑血流对抗大鼠缺血性脑水肿；

It could selectively reduce the vertebral artery resistance in anesthesia dogs and antagonize brain edema in rats by increasing the blood flow of ischemia regions ;

结论：3种药物均有抗缺血性脑水肿作用，利多卡因抗缺血性脑水肿作用优于复方甘油，与甘露醇作用相同。

CONCLUSION : The three drugs all have the effect in anti ischemia cerebral edema , the effect of lidocaine is better than that of compound glycerin , and the same as that of mannitol .

也提示脑梗塞急性期（尤其3天内）适量应用阿片受体拮抗剂或激动剂，有利于减轻缺血性脑水肿，缓解神经受损症状。

It is also indicated that in acute stage of CI ( especialy within 3 days ), the administration of opium antagonists and agonists in moderate dosage may reduce the ischemic cerebral edma and neurological deficits .

脑缺血时血脑屏障破坏导致脑血管通透性增加，是缺血性脑损伤与水肿形成病理发展过程中的重要因素。

During brain ischemia , the disruption of BBB results in the increase of brain vascular permeability and it could further promote ischemic brain injury and brain edema .