羟醛缩合

气相羟醛缩合法制MA及MMA研究进展

Progress in the Research on Vapor-phase Aldol Condensation to MA and MMA

以环己酮为起始原料，经Stork烯胺反应、羟醛缩合、消除、芳构化制得酮基布洛芬，总收率43.2%。

Ketoprofen was synthesized from cyclohexanone via stork enamine reaction , aldol condensation , elimination reaction and aromatization in overall yield of about 43.2 % .

（4S）-苯氧基-（S）-脯氨酸催化直接不对称羟醛缩合反应

Direct Asymmetric Aldol Reactions Catalyzed by ( 4S ) - Phenoxy - ( S ) - proline

在不需要惰性气体保护的条件下，将由水滑石煅烧所得到的Mg-Al复合氧化物直接加入到羟醛缩合的水相反应体系中。

Mg-Al mixed oxide , which is originated from hydrotalcite , is directly added into the aqueous-phase reaction system of Aldol condensation without protection of inert gas .

羟醛缩合反应是形成C-C键的重要反应之一，其传统的催化反应工艺是在酸或碱的水溶液中进行的。

Aldol reaction is an important response to the formation of one C-C bond , the traditional catalytic reaction process is carried out in acid or alkaline aqueous solution .

本论文以线型聚苯乙烯为可溶性载体，成功制备了线型聚苯乙烯支载的海因手性辅助试剂，研究其在羟醛缩合反应、Mannich反应中的不对称诱导效果。

In this thesis , we successfully synthesized soluble non-cross-linked polystyrene ( NCPS ) supported hydantoin chiral auxiliary and investigated its asymmetric induction effect in aldol reaction , mannich reaction . 1 .

聚合物支载手性辅助试剂在不对称羟醛缩合反应、烷基化反应、Mannich反应、D-A反应等中得到广泛的应用，取得良好的不对称诱导和分离纯化效果。

Polymer-supported chiral auxiliary has been widely applied in asymmetric aldol reaction , alkylation reaction , Mannich reaction , D-A reaction and obtained a good asymmetric induction and purification effect .

基于交叉羟醛缩合反应的多元醇类化合物的研究进展

Progress in Synthesis of Polyhydric Alcohols Based on Cross - Aldol Condensation

S-脯氨酸催化丙酮与2,2-二甲基丙醛不对称直接羟醛缩合反应过渡态的理论研究

Transition State Study on the S-Proline-catalyzed Direct Aldol Reaction between Acetone and 2,2-Dimethyl-propionaldehyde

交叉羟醛缩合反应制二苯叉丙酮实验的研究

Experimental research on preparation of dibenzalacetone by the crossed reaction of aldol condensation

双环哌啶化合物176催化直接羟醛缩合反应的活性研究还在进行之中。

The application of 176 to the catalytic direct aldol reaction is underway .

丙二酸发生羟醛缩合时的二次脱羧反应

The second decarboxylation of malonic acid in aldol condensation

相转移催化下的交叉羟醛缩合反应

Crossed aldol condensation reaction by phase transfer catalyzed

脯氨酸催化不对称羟醛缩合反应机理研究进展

Progress in the Study on the Reaction Mechanisms of Proline-Catalyzed Asymmetric Direct Aldol Reactions

然后，用羟醛缩合反应合成10个α-细辛醚类衍生物。

Then , 10 α - asarone derivatives were obtained with aldol condensation reaction .

气固相催化羟醛缩合合成α-氯丙烯酸甲酯的研究

Study on Synthesis of Alpha - methyl Chloroacrylate by the Vapor - phase Aldol Condensation

不对称羟醛缩合反应是有机合成中立体选择性地形成碳碳键的最重要方法之一。

The asymmetric aldol reaction is one of the most important methods of forming carbon-carbon bonds .

本文介绍了用正庚醛和苯甲醛通过羟醛缩合合成甲位戊基桂醛。

This paper introduced the preparation of a-amyl cinnamaldehyde via aldol condensation of n-heptanal and benzaldehyde .

羟醛缩合可以形成新的碳-碳键，增长碳链，是一类重要的有机反应。

Aldol condensation is an important organic reaction which leads to the formation of new C-C bond .

甲醛和丁醛在碱性催化剂的存在下，进行羟醛缩合反应，制备2，2二羟甲基丁醛。

Using inorganic base as a catalyst , 2,2-dimethylolbutyraldehyde was prepared by the aldol condensation from formaldehyde and butyraldehyde .

以丙酮为原料，经羟醛缩合、脱水反应、卤仿反应和还原反应合成了3-甲基-2-丁烯-1-醇。

Methyl 2 buten 1 ol was synthesized from actone by Aldol , dehydration reaction , haloform reaction and reduction reaction .

在碱性催化剂三乙胺的存在下，甲醛和正丁醛发生羟醛缩合反应生成产物2，2-二羟甲基丁醛。

With triethylamine as catalyst , 2,2-dihydroxymethylbutanal ( DMB ) was synthesized with formaldehyde and butyraldehyde taking place aldol condensation reaction .

近年来，有机小分子已经被证实可以有效地催化醛酮的直接羟醛缩合反应。

It has been known that small organic molecules can catalyze the direct aldol reaction between aldehydes or between aldehyde and ketone .

苯甲醛和乙醛以近临界水为反应介质，可在无外加催化剂和有机溶剂条件下发生羟醛缩合反应，生成肉桂醛。

Cinnamaldehyde was synthesized successfully through the reaction of phenylaldehyde with acetaldehyde in near-critical water , without any added catalyst or organic solvent .

以环戊酮和脂肪醛系列为原料，经过羟醛缩合、催化加氢、氧化反应，三步制得丁位内酯系列产品。

δ - Butyrolactone series products are synthesized via aldol condensation , catalytic hydrogenation and oxidation reaction based on cyclopentanone and aliphatic aldehyde .

在室温下使用超声波或无溶剂条件下，4二茂铁基3烯2酮和芳香醛的羟醛缩合能以83%～97%的收率得到1芳基5二茂铁基1,4二烯3酮。

Aldol condensation of 4-ferrocenyl-3-buten-2-one with aromatic aldehydes afforded 1-aryl-5-ferrocenyl-penta-1,4-dien-3-one in 83 % ~ 97 % yields under ultrasound irradiation or solvent-free condition at room temperature .

结果表明：在水中和聚乙二醇中，组氨酸是羟醛缩合反应的一种良好的催化剂，在这两种溶剂的反应能得到高的化学产率；

It reveals that histidine is a good aldol catalyst for synthesis of β - hydroxylketones in water and in PEG , giving good to excellent yields of the respective products .

新型手性双氮氧铟络合物催化酮的不对称烯丙基化反应研究一种新型手性催化剂的合成及其催化的不对称羟醛缩合反应

Studies on Enantioselective Allylation of Ketones Catalyzed by a Novel Chiral N , N ' - Dioxide Indium (ⅲ) Complexes ; Synthesis of a Small Organic Molecule and Its Application to Asymmetric Aldol Reaction

我们以各种天然氨基酸为起始原料合成手性离子液体并把其中一种手性有机催化剂应用于羟醛缩合反应中的研究。

The synthesis of new chiral ionic liquids , started from natural amino acid , was discussed , and the performances of the prepared ILs as an new catalyst were evaluated by aldol reaction .

此类化合物合成的第一步反应均是基于交叉羟醛缩合反应，同时又根据所用碱性催化剂的不同分为钙法、钠法和混合碱法等；

The first step of synthesis for these compounds are all based on cross-aldol condensation , and can be also divided into calcium method , sodium method and mixed alkali method namely due to the different alkaline catalysts used in the reaction .