致畸因子

维生素A酸是常见的一类化学致畸因子，可引起各种心脏畸形，如主动脉骑跨、室间隔缺损等。

Retinoic acid is a chemical teratogen which causes varieties of congenital cardiac malformations , such as overriding aorta , ventricular septal defect .

提示CHD与TOX感染密切有关，先天性TOX感染可能是CHD的致畸因子。

It is suggested that TOX infection be closely correlated with CHD as a teratogenic factor .

目的探讨大鼠骨骼发育过程中环境类致畸因子对成骨细胞中胰岛素样生长因子（insulin-likegrowthfactors，IGFs）家族基因表达的抗雌激素作用。

Objective To investigate the antiestrogenic effect of environment teratogen on the gene expression of insulin-like growth factors ( IGFs ) family in osteoblast cells during rat skeleton development .

出生缺陷环境致畸因子识别空间探索分析

Spatial Exploratory Data Analysis of Birth Defect Risk Factors ' Identification

目的通过空间探索分析获取出生缺陷环境致畸因子的有效线索，为致畸因子识别奠定基础。

Objective To acquire effective clues for identification of environmental risk factors to birth defects .