血红素氧合酶

血红素氧合酶（HO）是体内产生CO的限速酶。

Heme oxygenase ( HO ) is the rate-limiting enzyme of the CO production , and HO-1 is the induced form of HO .

目的观察肝硬化大鼠肺脏中血红素氧合酶（HO）的表达与定位，探讨血红素氧合酶-内源性一氧化碳在肝硬化时肺脏病变的作用。

Objective To observe the function of heme oxygenase ( HO ) in the lung damage in hepatic cirrhosis rats .

支架置入术后血清C反应蛋白浓度与血红素氧合酶-1活性变化及意义

The changes of serum C-reaction protein concentration and heme oxygenase-1 activity after coronary sten implantation and its significance

缺氧性肺动脉高压与血红素氧合酶1及其mRNA变化的关系

The relationship between hypoxic pulmonary hypertension and changes of HO 1 and its mRNA

血红素氧合酶-1对动脉粥样硬化大鼠MDACD68及MMP-9的影响

Effects of heme oxygenase-1 on MDA CD68 and MMP-9 in atherosclerotic rat

以酶化学法观察其对脾细胞血红素氧合酶1（HemeOxygenase1，HO1）活性的影响。

The heme oxygenase-1 ( HO-1 ) activity was analyzed by the enzyme assay .

目的探讨血红素氧合酶（HO-1）和内源性一氧化碳（CO）在哮喘患者中的改变及可能的作用。

Objective To explore the change and relevant effect of heme-oxygenase-1 ( HO-1 ) and endogenous carbon-monoxide in asthma patients .

目的探讨慢性肺心病肺动脉高压患者中血红素氧合酶（HO）-1和内源性一氧化碳（CO）的变化。

Objective To study the changing of heme-oxygenase-1 ( HO-1 ) and endogenous carbon-monoxide ( HbCO ) in patients with chronic pulmonary hypertension .

目的研究诱导型血红素氧合酶-1（HO-1）在活动性溃疡性结肠炎（UC）患者结肠中的表达，探讨气体信使分子一氧化碳（CO）在UC发病机制中的可能作用。

Objective To detect the expression of heme oxygenase-1 ( HO-1 ) in active ulcerative colitis ( UC ) .

Cajal间质细胞与血红素氧合酶-2在糖尿病大鼠结肠组织中的改变

Interstitial Cells of Cajal and Heme Oxygenase-2 Changed in the Colon of Diabetic Rat

探讨血红素氧合酶-1（HO-1）在豚鼠哮喘模型中的表达特点。

The expression of heme oxygenase 1 ( HO 1 ) in asthmatic guinea pigs was investigated .

结论动脉粥样硬化进程中，HO/CO和NOS/NO系统显示出互补及代偿性调节作用，血红素氧合酶系统有可能通过对NO和NOS的调节和代偿机制抑制AS病变的发展。

Conclusion The reciprocal relationship between HO-1 / CO and NOS / NO system in atherosclerosis may play the inhibitory role against atherosclerotic lesion .

目的：通过制备豚鼠变应性鼻炎动物模型，观察并分析内源性一氧化碳（CO）的限速酶血红素氧合酶1（HO1）在豚鼠鼻黏膜组织中的表达。

Objective : To study the expression of a specific inhibitor of endogenous carbon monoxide ( CO ) generating enzyme Heme oxygenase - 1 ( HO-1 ) in allergic rhinitis guinea pigs .

血红素氧合酶-1（HO-1）是血红素氧合酶的诱导型，能催化血红素分解生成CO、胆红素和铁。

Heme oxygenase-1 ( HO-1 ) is an inducible isoform of heme oxygenase , it can degrade heme into carbon monoxide , bilirubin and iron .

目的探讨p38α通路和血红素氧合酶（HO-1）在乳腺癌发生和耐药中的作用。

Objective To investigate the role of p38 α pathway and HO-1 in the genesis and chemotherapy resistance of breast cancer .

研究的背景与目的：血红素氧合酶（HemeoxygenaseHO）是催化血红素降解的起始酶和限速酶。

Background and objective : Heme oxygenase ( HO ) catalyzes the oxidation of heme to carbon monoxide , biliverdin , and iron .

目的：探讨血红素氧合酶-1（HO-1）/一氧化碳（CO）径路在肺缺血-再灌注损伤中的作用。

AIM : To investigate the effect of heme oxygenase-1 ( HO-1 ) / carbon monoxide ( CO ) system on pulmonary ischemia-reperfusion injury ( PIRI ) in rabbits .

目的观察后肢体缺血/再灌注是否诱发心脏血红素氧合酶1（HO-1）的表达。

Objective To observe whether hind limb ischemia / reperfusion induces the haem oxygenase 1 ( HO-1 ) expression in rat heart .

目的探索血红素氧合酶（HO-1）对体内血栓形成的调节功能，并探求其可能机制。

Objective To study the potential function and mechanism of heme oxygenase-1 ( HO-1 ) in regulating platelet reactivity and arterial thrombosis .

EAE大鼠SFO血红素氧合酶-1基因和蛋白表达的变化

The dynamic changes of heme oxygenase-1 mRNA and protein express at subfornical organ in rats with experimental allergic encephalomyelitis

血红素氧合酶（HemeOxygenase，HO）是血红素降解的起始酶和限速酶，在体内分解血红素生成一氧化碳（CarbonMonoxide，CO）、胆绿素和自由铁。

Heme oxygenase ( HO ) is an initial and limiting enzyme of heme oxidization , which can catalyze the heme into carbon monoxide ( CO ), biliverdin and free iron .

目的由血红素氧合酶（HO）催化血红素分解代谢而形成的一氧化碳（CO）可能作为一种新的内源性介质参与感染性休克一系列病理生理过程。

Objective Endogenous carbon monoxide ( CO ), which was mainly produced through the metabolism of heme catalysed by hemeoxygenase ( HO ), was suggested to play a role in the pathophysiology of septic shock .

目的：探讨氯化亚锡（SnCl2）对大鼠肾急性缺血再灌注损伤的改善作用和血红素氧合酶-1（HO-1）表达的影响。

Aim : To investigate the protective effect of heme oxygenase-1 ( HO-1 ) induced by SnCl_2 on renal ischemia and reperfusion injury in rats .

目的使用血红素氧合酶抑制剂，探讨血红素氧合酶一氧化碳（HOCO）系统在大鼠肝硬化高动力循环中的作用。

Purpose To explore the role of heme oxygenase ( HO ) and carbon monoxide ( CO ) in hyperdynamic circulation of cirrhotic rats . Methods Liver cirrhosis was induced by percutaneous administration of carbon tetrachloride .

目的：探讨活化蛋白-1（AP-1）阻断剂curcumin对注射脂多糖大鼠肺组织血红素氧合酶（HO-1）表达的转录调节机制。

AIM : To study the regulatory effect of curcumin on expression of heme oxygenase-1 ( HO-1 ) in the lung of rat treated with LPS .

目的克隆血红素氧合酶-1（HO-1）基因，并构建真核表达载体，建立重组HO-1蛋白的血管内皮表达细胞系。

Objective To construct eukaryotic expression vector of hemeoxygenase-1 ( HO-1 ) gene and establish vascular endothelial cell line ( ECV304 ) expressing recombinant HO-1 protein .

目的观察大鼠缺血再灌注时骨骼肌中血红素氧合酶-1（HO-1）表达的变化。

Objective To observe the changes of heme oxygenase 1 ( HO 1 ) expression in the skeletal muscle after ischemia reperfusion of hind limb in rats .

目的：观察缺氧大鼠肺小血管壁缺氧诱导因子1α（HIF-1α）和血红素氧合酶1（HO-1）基因表达。

AIM : To observe the expression of hypoxia inducible factor-1 α ( HIF-1 α) gene and heme oxygenase-1 ( HO-1 ) gene in pulmonary arteries in hypoxic rats .

目的研究血晶素（Hemin）对缺氧大鼠肺组织诱导型血红素氧合酶（HO1）表达的影响。

AIM To investigate the effect of Hemin on the expression of inducible heme oxygenase ( HO 1 ) in hypoxic rat lung tissue .

随着研究的逐步深入，人们越来越关注血红蛋白代谢的限速酶&血红素氧合酶（HemeOxygenase，HO）在脑出血的作用及其机制。

With the approach of experiments and researches , more and more attention are payed to the effect and mechanism of heme oxygenase , the rate-limiting enzyme of hemoglobin metabolism .