角化过度

病理上尖锐湿疣以增生为主，尤以异型增生、角化过度及角化不全为特征。

Pathological changes of condyloma are characterized as proliferation , especially dysplasia , hyperkeratosis and parakeratosis .

结果脂溢性角化病的基本病理特征为角化过度、棘层肥厚、乳头状瘤样增生，肿瘤的下端与正常表皮平行。

Results The basic histological characteristics of seborrheic keratosis were hyperkeratosis , acanthosis , papillomatosis and that the inferior end of tumor was paralled to normal epidermis .

光化学疗法治疗手角化过度性湿疹60例临床疗效观察

Clinical Effect with Photo Chemotherapy for 60 Sufferers with Hand Eczema

表皮松解性角化过度型鱼鳞病二例及其基因突变的研究

Gene Mutations in Two Sporadic Cases of Epidermolytic Hyperkeratosis Ichthyosis

目的研究二例表皮松解性角化过度型鱼鳞病患者基因突变情况。

Objective To identify gene mutations of two cases of epidermolytic hyperkeratosis ichthyosis .

肢端皮肤角化过度增生症的手术治疗

Surgical treatment of excessive hyperplasia symptom of skin keratosis at the limb ends

报告1例持久性豆状角化过度症。

A case of hyperkeratosis lenticularis perstans is reported .

由角化过度型甲盘状红斑狼疮进展为系统性红斑狼疮：治疗上的困惑

Hyperkeratotic nail discoid lupus erythematosus evolving towards systemic lupus erythematosus : Therapeutic difficulties

表皮松解性角化过度家系基因突变研究

Keratin Gene Mutation of an EHK Family

表皮松解性角化过度鱼鳞病伴侏儒1例

Q & A on Sex Epidermolytic hyperkeratosis ichthyosis complicated by dwarf : a case report

显著角化过度型汗孔角化症1例

Obvious hyperkeratosis porokeratosis : a case report

解毒润肤喷剂治疗角化过度型足癣60例疗效观察

Effect Observation of 60 Cases of Cornification Excess Type Tinea Pedis Treatment Using Detoxifcation Lubricant Spray

躯干部皮肤明显干燥，皮肤角化过度，呈皮革样变化。病理活检为鱼鳞病，耳科检查为先天感音神经性耳聋，眼科检查为角膜血管翳。

The diagnosis was ichthyosis in histopathological examination , congenital nerve deaf-mutism in otolaryngology and corneal pannus in ophthalmology .

目的观察盐酸特比萘芬（兰美抒）口服联合中药复方透骨草浸泡治疗角化过度型足癣的临床疗效。

Objective To observe the clinical efficiency of Terbinafine and Traditional Medicine Solution Compound in Treating Keratotic Tinea Pedis .

结果：动物表皮有一层角化过度的角质层，毛干消失，毛球结构不正常，毛囊内为一些角化物质，有的变为空囊腔。

Results : There is a excessively keratinized layer in the animal epidermis , loss of hair shaft , abnormal structure of hair bulbs .

腹部皮损组织病理学检查示，表皮角化过度，颗粒层变薄，棘层不规则增厚，真皮浅层散在噬色素细胞，血管周围有淋巴细胞浸润。

Pathological changes of the abdomen showed hyperkeratosis and mild irregular acanthosis , the granular layer was thin and melanophage and perivascular lymphocytic infiltration in upper dermis .

雅司病晚期是在初期感染五年以后，特征是鼻子、骨头坏损，手掌/足底角化过度。

Late yaws appears after five years of the initial infection and is characterized by disabling consequences of the nose , bones and palmar / plantar hyperkeratosis .

砷是一种剧毒的类金属，能引起机体急性和慢性损伤包括皮肤损害、角化过度、黑脚病、癌症。

Arsenic , which is a highly poisonous metalloid , causes acute and chronic adverse health effects , including skin lesions , hyperkeratosis , blackfoot disease and cancer .

组织病理改变主要为角化过度伴灶状角化不全，基底层液化变性，真皮浅层可见淋巴细胞大致呈带状分布，并可见嗜酸性粒细胞和浆细胞浸润。

Histopathology showed hyperkeratosis accompanied by focal parakeratosis , vacuolar degeneration of basal layer and superficial dermal bandlike infiltration composed of lymphocytes , and also eosinophil and plasma cells .

组织病理检查为表皮角化过度，颗粒层增厚，基层灶性液化变性，真皮浅层可见带状炎症细胞浸润。

The skin biopsy showed hyperkeratosis , hyperplasia of granular layer and liquefaction degeneration of basal cells in the epidermis with band-shaped infiltration of lymphocytes , histiocytes , and melanophages in the superficial dermis .

组织病理学检查：角化过度、角质层内及角质层下裂隙，角质层内可见变性坏死的中性粒细胞和角蛋白碎屑，棘层细胞及真皮乳头层轻度水肿，嗜酸性粒细胞少见。

The skin biopsy showed hyperkeratosis of the stratum corneum and intracorneal and subcorneal cleft containing polymorphonuclear leucocytes , sparse eosinophils , and keratinous debris with mild edema of the epidermis and papillary dermis .

目的介绍肢端皮肤角化过度增生症10例的治疗体会，其中掌跖角化病9例，疣状表皮结构不良1例。

Objective We introduce the experience of treating 10 cases with excessive hyperplasia of skin keratosis at the limb end . There were 9 cases of palmar and plantar keratosis and 1 case of epidermodysplasia verruciformis .

模型对照组：模型组兔耳廓皮肤表面复层鳞状上皮增厚，部分毛囊扩张呈漏斗状，毛囊内角化过度，毛囊壁破损，周围可见炎性细胞浸润。

Model control group : rabbit ear model group stratified squamous epithelial surface of the skin thickening , was funnel-shaped expansion of some hair follicles , hair follicle hyperkeratosis , follicle wall damage , peripheral inflammatory cells infiltration .

目的：通过对解毒润肤喷剂治疗角化过度型足癣60例的疗效观察和评价，认识中医解毒润肤外治法在治疗本病中的优势。

Objective : To recognize the advantage of " detoxifcation lubricant external treatment " in treating Cornification Excess Type Tinea Pedis through the effect observation and evaluation of 60 cases if this disease treatment using detoxifcation lubricant spray .

结论：解毒润肤喷剂治疗角化过度性足癣效果良好，解毒润肤外治法在治疗本病上有相当的优势，值得进一步研究及推广。

Conclusion : The effect of detoxifcation lubricant spray in treating Cornification Excess Type Tinea Pedis is god . Detoxifcation lubricant external treatment has quite predominance in treating this disease and it is valuable to further research and popularize .

2002年12月31日左前臂皮损部位行活检，病理活检报告：表皮角化过度，角化不全，真皮乳头高度水肿，真皮密集的成熟中性粒细胞浸润，有核尘，并可见毛细血管扩张。

On Dec 31 , 2002 , biopsy of cutaneous lesions on left forearm showed hyperkeratosis of epidermis , parakeratosis , severe edema of dermal papillae , intensive infiltration of mature neutrophil in dermis , nuclear dust and capillary telangiectasia .

方法：对60例角化过度型足癣患者用解毒润肤喷剂治疗14天，于治疗前、治疗后进行真菌培养分离鉴定病原菌及观察评分，并进行统计学分析，评定疗效。

Methods : Using detoxifcation lubricant spray to treat the 60 patients with Cornification Excess Type Tinea Pedis for 14 days . Separate and identify the pathogenic bacterium by cultivating epiphyte before and after the treatment , rate the observation , execute a statistics analysis and assess the effect .

上皮的变化包括棘细胞增生，空泡变性，不全角化，过度角化和坏死等。

Epidermal changes consist of acanthosis , vacuolar degeneration , parakeratosis , hyperkeratosis and necrosis .

结论在寻常型银屑病、脂溢性角化症（棘层肥厚型、角化过度型及腺样型）、日光性角化症和鳞状细胞癌，Survivin表达阳性，呈现不同程度的染色；

Conclusion : Survivin expression is observed in psoriasis vulgaris 、 seborrheic keratosis ( acanthotie type 、 hyperkeratotic type and adenoid type )、 solar keratosis and squamous cell carcinoma .

先证者双肘膝关节毛囊角化性丘疹，足趾及跖部灶性胼胝样角化过度，20甲营养不良。

Proband also had special clinical feature including follicular hyperkeratosis on the elbows and knees , and onychodystrophy of20 nails as well .