遗传性肾炎

遗传性肾炎（Alport综合征）&一个家系的调查报告

Hereditary nephritis ( alport 's syndrome ) & on an of pedigree

名为Alport综合征的遗传性肾炎。病人通常表现为神经性耳聋及眼病。

This is a type of hereditary nephritis known as Alport 's syndrome in which patients may also manifest nerve deafness and eye problems .

X连锁显性遗传性肾炎一家系相关基因排除定位分析

A Exclusive Mapping Analysis on the Gene Associated with X-linked Dominant Inherited Nephritis in One Pedigree

Alport综合征又称遗传性肾炎，患者往往并发肾外综合征，如神经性耳聋和眼疾等。

Alport syndrome ( AS ) is a hereditary kidney disease associated with extrarenal complications , such as sensorineural deafness and eye abnormalities and so on .

方法：采用特异性抗Ⅳ型胶原α3和α5链NC1区域的单克隆抗体，对4例正常人及43例临床疑诊为遗传性肾炎患者的肾脏组织进行了间接免疫荧光染色。

METHODOLOGY This study included 49 patients who satisfied the clinical criteria for the diagnosis of hereditary nephritis . Type ⅳ collagen α 3 and α 5 chains in renal biopsy sections were detected with indirect immunofluorescence assay .

肾小球薄基底膜病及遗传性肾炎的超微病理诊断

Ultrastructural pathologic diagnosis of thin glomerular basement membrane disease and Alport syndrome

Ⅳ型胶原α3、α5链免疫组化检测在遗传性肾炎诊断中的意义

Diagnostic value of immunohistochemical study of type ⅳ collagen α 3 and α 5 chains on patients with hereditary nephritis

本文着重分析遗传性肾炎的临床表现，就其早期诊断线索和遗传方式提出讨论。

Make a special effort to analysis chinical feature , the discussed inheritance patter and diagnosis indication rapid of hereditary nephritis in article .

目的：评价电镜检查对小儿遗传性进行性肾炎的诊断意义。

Objective : To evaluate the significance of electron-microscopy in the diagnosis of children Alport syndrome .