锚定蛋白
- 名Ankyrin;anchorin
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再以带有FLAG标签的南极假丝酵母脂肪酶B蛋白的C末端同3种锚定蛋白N端融合,并利用免疫荧光显微镜检测,证明新构建的毕赤酵母展示通用载体是成功的。
Then tagged with a FLAG Candida antarctica lipase B protein with three kinds of C-terminal N-anchored fusion protein and used immunofluorescence microscopy , that the newly constructed yeast display common carrier is successful .
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神经元GPI锚定蛋白结构与功能研究进展
A Brief View on the Structure and Function Study of the Neuronal GP-anchored Proteins
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GPI锚定蛋白抗体CD55、CD59及RET在贫血诊断中的意义探讨
Investigation of anchoring protein antibodies CD55 / CD59 and RET on the diagnostic significance of anemic patients
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此外,他们以抗CD146抗体和AnnexinV(锚定蛋白)作为标记,通过流式细胞仪测定了血样本中循环凋亡细胞的水平。
In addition , they quantified circulating apoptotic cells by flow cytometry of blood samples labeled with anti-CD146 antibody and Annexin V.
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已知GPI锚定蛋白由磷脂酰肌醇,糖链和蛋白部分组成。一般认为影响GPI锚定蛋白在脂筏中定位的主要因素是GPI锚的脂质部分。
So making clear the location mechanism of GPI-anchored proteins in lipid raft and influencing factor is very important .
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作为脂筏的组成成分,GPI锚定蛋白的功能与脂筏关系密切。GPI锚定蛋白在脂筏内外分布的不同常影响其功能。
As the main component of lipid rafts , the functions of GPI-anchored proteins are related closely to lipid rafts .
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GPI锚定蛋白可以通过其尾部脂质GPI结构自然地整合到细胞膜上。
This method involves purified glycosyl-phosphatidylinositol ( GPI ) - anchored proteins which can spontaneously incorporate their lipid tail into cell membranes .
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不同脂酰链对GPI锚定蛋白在脂筏中定位的影响
The Effects of Different Fatty Acyl Chains on the Distribution of Glycosylphosphatidylinositol ( GPI ) - anchored Proteins in the Lipid Rafts
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胰岛素受体底物-1(Insulinreceptorsubstrate-1,IRS-1)作为多位点的锚定蛋白,连接受体激酶和信号蛋白质,引起受胰岛素调节的许多细胞内的多种功能的活化。
Insulin receptor substrate-1 ( IRS-1 ) acts as a multisite docking protein that binds signal proteins and links the receptor kinase to a number of cellular functions that are regulated by insulin .
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在细胞表面,GPI锚定蛋白常与鞘脂(包括鞘糖脂和鞘磷脂),胆固醇等聚集在一起形成具有特定结构和功能的质膜微区,称GPI微域(GPImicrodomain)。
GPI-anchored proteins often gather with sphingolipids ( including sphingomyelin and glycosphingolipid ) and cholesterol to form special plasma membrane microdomains ( GPI microdomain ) .
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细胞表面工程,又称GPI锚定蛋白转移法,是一种不依赖基因转移而能够在细胞膜上表达新蛋白的有效方法。
Cell-surface engineering technique , also named as GPI-anchored protein transfer , has become an attractive strategy to express new proteins on cell membranes without gene transfer .
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结论:降低GPIPLD活性能增加骨髓单个核细胞对纤连蛋白的黏附率,与此同时,骨髓单个核细胞上GPI锚定蛋白CD24的表达增强。
It is concluded that depression of GPI-PLD activity can increase the adhesion rate of bone marrow mononuclear cells from the patients while the CD24 expression is enhanced .
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精子A激酶锚定蛋白的研究进展
Progress in Researches on A-kinase Anchor Proteins in Sperm
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目前,已发现多种糖基化磷脂酰肌醇锚定蛋白与动脉粥样硬化的发生、发展密切相关。
Presently , it has been found that the occurrence and development of atherosclerosis were closely correlated with glycosylphosphatidylinositol-anchored proteins .
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本论文在拟南芥和水稻基因组测序工作完成的基础上,利用生物信息学的方法,鉴定和分析了两种模式植物基因组的锚定蛋白基因。
Based on genome sequencing of Arabidopsis and rice , this paper identified and analyzed the ANK genes of two model plants using the methodes of bioinformatics .
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心肌锚定重复序列蛋白CARP的研究进展
Progress in the study on cardiac ankyrin repeat protein
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水稻锚蛋白基因家族分析和锚定膜蛋白的表达模式研究
Analysis on Rice ANK Gene Family and Expression Pattern of Ankyrin-transmembrane Genes
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目的:许多膜蛋白(包括酶,细胞粘附因子,受体等)依靠糖基磷脂酰肌醇锚定于细胞质膜表面,又称GPI锚定蛋白。
Objective : Many membrane proteins ( including enzyme , cell adhesion molecule , receptor ) are anchored on plasma membrane by glycosylphosphatidylinositol , and named glycosylphosphatidylinositol ( GPI ) - anchored proteins .