黏连蛋白
- 网络fibronectin;cohesin
-
方法采用体外重组基底膜侵袭实验方法,加入不同趋化剂:成纤维细胞条件培养液、纤维黏连蛋白(FN)、条件培养液与FN联合;
Method Reconstituted basement membrane invasion experiment was employed , and conditioned medium , fibronectin ( FN ), and a combination of conditioned medium and FN were respectively used as chemoattractants was placed in the lower compartment of the chamber .
-
实验结果可见,PLA-801D细胞对鼠尾胶原和纤黏连蛋白的粘附作用均明显强于PLA-801C细胞(p0.01)。
Compared with PLA-801C cells , PLA-801D cells showed significantly stronger adhesion to both rat collagen and fibronectin ( p 0.01 ) .
-
层黏连蛋白促进人晶状体上皮细胞蛋白激酶B的活性
Laminin increase protein kinase B activity of human lens epithelial cells
-
整合素α1、层黏连蛋白和IL-1α在大鼠肝再生过程中的表达变化
The changes of expression of integrin α 1 , laminin and il-1 α and their roles during rat liver regeneration
-
人肝再生增强因子抑制层黏连蛋白B1链基因转录活性的研究
Study on the effects of human augmenter of liver regeneration on laminin B1 chain gene promoter
-
纤黏连蛋白重组多肽CH50抑制黑色素瘤MMP-2和MMP-9表达、激活的研究
Recombinant Polypeptide CH50 of Fibronectin Inhibits the Expression and Activation of Matrix Metalloproteinase 2 and 9 in Melanoma
-
层黏连蛋白和纤维连接蛋白对传代人晶状体上皮细胞生长和Cx43表达的影响
The Effects of laminin and fibronectin on human lens epithelial cells subculture characters and Cx43 expression
-
目的:研究层黏连蛋白(LN)和IV型胶原在外阴白斑和外阴鳞癌中的表达。
Objective : To determine the expression of laminin ( LN ) and type IV collagen in patients with leukoplakia and squamous cell carcinoma of vulvae .
-
目的探讨大肠癌患者手术前后血清层黏连蛋白(LN)含量的动态检测及其临床意义。
Objective To study the change of serum Laminin ( LN ) in preoperative and postoperative patients with colorectal cancer and its clinical significance .
-
方法纤黏连蛋白与A2780人卵巢癌细胞相互作用后,用反转录PCR观察MMPmRNA的表达;
Methods Following adhesion of ovarian cancer cells A2780 to fibronectin , mRNA expression of MMP cells were assayed by reverse transcription-polymerase chain reaction ( RT-PCR ) .
-
目的探讨层黏连蛋白(LM)Ⅳ胶原在前列腺不同疾病中的表达及意义。
Objective To explore the expression and significance of laminin ( LM ) and collagen ⅳ( C ⅳ) in all kinds of prostate tissue .
-
辛伐他汀对糖尿病肾病患者UALB及TGFβ1、IV型胶原和层黏连蛋白的影响
Effect of simvastatin on the excretion of urine microalbuminuria , TGF β 1 , Type IV collagen and laminin in patients with diabetic nephropathy
-
目的观察胆红素干预对肺气肿大鼠模型肺组织和肺泡Ⅱ型上皮细胞(ATⅡ)层黏连蛋白(Ln)及表皮生长因子(EGF)表达的影响。
Objective To explore the effects of bilirubin on expression of laminin ( Ln ) and epidermal growth factor ( EGF ) in lung tissue and in type ⅱ pneumocytes ( AT ⅱ) in smoking rats .
-
目的研究纤维连接蛋白(FN)、层黏连蛋白(LN)、细胞外基质金属蛋白酶诱导因子(EMMPRIN)在食管癌的表达,探讨其临床意义。
Objective To study the expression and clinical significance of fibronectin ( FN ), laminin ( LN ) and extracellular matrix metalloproteinase inducer ( EMMPRIN ) in esophageal carcinoma .
-
已有实验证实,CTGF可通过介导糖基化终末产物这一经典途径促进肾脏系膜细胞合成胶原蛋白和纤维黏连蛋白,从而参与了肾脏纤维化的进展。
Experiments have been confirmed , CTGF mediated by advanced glycation end product of this approach for kidney mesangial cells to synthesize collagen and fibronectin , which participated in the progress of renal fibrosis .
-
结论纤黏连蛋白重组多肽CH50可以抑制肿瘤微环境中基质金属蛋白酶MMP-2和MMP-9的表达和激活,从而抑制黑色素瘤生长及侵袭能力。
Conclusion CH50 can effectively suppress both the expression and activation of MMP 2 and MMP 9 in tumor microenvironment , therefore it may act as a potent inhibitor for the prevention of the invasion and metastasis of melanoma .
-
Netrin-1是层黏连蛋白相关的分泌蛋白,它在调节神经轴突生长、白细胞迁移的过程中发挥重要作用;同时,它还参与调控肿瘤细胞侵袭和转移能力。
Netrin-1 is a diffusible laminin-like chemotactic protein which has been shown to act as guidance cues for developing axons and migrating neuroblasts and it also plays an important part in the regulation of the apoptosis and invasion of tumor cells .
-
人喉癌细胞层黏连蛋白受体的表达和功能
Expression and function of laminin receptor in laryngeal squamous cell carcinoma
-
皮肤低温储存后纤维连接蛋白和层黏连蛋白表达的研究
The immunohistochemical study of fibronectin and laminin after cryopreserved human skins
-
盆腔结缔组织炎大鼠模型的层黏连蛋白表达
Laminin Expression in the Rat Model of Pelvic Connective Tissue Inflammation
-
先天性肌营养不良的诊断及层黏连蛋白表达的意义
Diagnosis of congenital muscular dystrophy and clinical significance of merosin expression
-
非洲绿猴层黏连蛋白受体的克隆、表达及纯化
Cloning , Expression and Purification of African Green Monkey Laminin Receptor
-
外源性透明质酸对创面纤维黏连蛋白表达的影响
Effect of exogenous hyaluronan on the expression of fibronectin at wound area
-
Ⅳ型胶原和层黏连蛋白与不孕症的关系
Relations of collagen type ⅳ and laminin expression with infertility
-
上皮型钙黏附蛋白和层黏连蛋白在葡萄胎组织中的表达
The expression of E-cadherin and laminin in hydatidiform mole and its significance
-
小鼠肾发育中层黏连蛋白表达的实验研究
The expression of laminin in the developing kidney of mouse
-
层黏连蛋白、纤连蛋白在人毛囊生长周期中的表达
Expression of laminin and fibronectin in the growth cycle of human hair follicles
-
肺气肿发生过程中胆红素对纤维黏连蛋白的影响
The influence of bilirubin on expression of Fn in rat pulmonary emphysema model
-
层黏连蛋白与其α6整合素受体对人肝癌细胞表型的调控作用
Laminin and its a6 integrin receptor in the regulation of human hepatocellular carcinoma cell phenotypes
-
层黏连蛋白受体反义核酸对卵巢癌细胞侵袭能力的影响
The Inhibitory Effect of 67 kD LN-R Antisense Oligonucleotides on Invasion and Metastasis of Ovarian Carcinoma Cells