兴奋性氨基酸
- 名excitatory amino acid
-
在脊髓,激活的胶质细胞还可以促进初级传入神经末梢释放P物质和兴奋性氨基酸而促进疼痛。
Activated glia also enhance the release of substance P and excitatory amino acid from primary afferents in the spinal cord .
-
兴奋性氨基酸加强高原低氧大鼠下丘脑前生长抑素原mRNA的表达
Excitatory amino acid enhance prepro Somatostatin mRNA expression induced by altitude hypoxia in the rat hypothalamus
-
测定脑缺血后和再灌注1、12和24h海马ATP含量、ATP酶活性和兴奋性氨基酸含量。
ATP content , ATPase activity and the content of ( excitatory ) amino-acids were assayed .
-
γ氨基丁酸(GABA)能抑制兴奋性氨基酸释放或对抗氨基酸毒性。
Gamma-aminobutyric acid ( GABA ) can inhibit the release of excitatory Glu or resist Glu toxicity .
-
酒精戒断对大鼠海马DG区部分兴奋性氨基酸的影响
Effect of Ethanol Withdrawal on Partial Excitatory Amino Acids Levels in the Hippocampus DG Inconscious Rats
-
结果复方丹参片能明显降低实验性AD大鼠脑内兴奋性氨基酸Glu的含量,升高抑制性氨基酸Gly和GABA的含量。
Results CDST significantly decreased the excitatory Glu content , and increased the inhibitory Gly and GABA contents .
-
灯盏花素对缺血再灌注沙土鼠海马ATP含量变化和兴奋性氨基酸释放的影响
Effects of erigeron on ATP content and release of excitatory amino-acids of the hippocampus after cerebral ischemia / reperfusion injury in gerbils
-
牛磺酸减轻兴奋性氨基酸对培养新生大鼠小脑皮层神经元的损害GDNF对减轻兴奋性氨基酸诱导大鼠小脑神经元变性作用的影响
GDNF effect on minimizing excitatory amino acid-induced degeneration in cerebellar cortical neurons of cultured neonatal
-
兴奋性氨基酸受体N-甲基-D-门冬氨酸(NMDA)受体在脑缺血损伤的病理过程中起重要作用。
N-methyl-D-aspartate ( NMDA ) receptors play an important role in the pathological processes of ischemic neuron injury .
-
结论复方丹参片降低兴奋性氨基酸含量,以对抗兴奋性氨基酸的毒性,这可能是其防治AD的机制之一。
Conclusion CDST could lower the toxicity of excitatory amino acid by decreasing its contents , which may be one of the mechanisms of CDST in prevention and treatment to AD.
-
非NMDA型兴奋性氨基酸受体促进大鼠伤害性传入引起的脊髓后角星形胶质细胞的激活
Non-NMDA Excitatory Amino Acid Receptor Promotes Activation of Astrocytes in the Spinal Dorsal Horn during Nociceptive Inputs in Rats
-
目的研究Mg~(2+)对神经细胞兴奋性氨基酸NMDA损伤的保护作用。
Objective To investigate the neuroprotective effects of Mg ~ ( 2 + ) on the damage by NMDA .
-
结论SPR术后脑脊液中兴奋性氨基酸下降,抑制性氨基酸上升及胆碱能神经元功能增强与肌痉挛解除和全身症状改善有关。
Conclusion The change of neurotransmitter relate to relieve spasm and improvement general symptom after patients were treated by SPR .
-
这一结果提示,NMDA和QA两种兴奋性氨基酸受体亚型均可能与皮层的感觉机能有关。
7 % . It is suggested that both NMDA and QA receptors may be involved in sensation process of cortex .
-
结论:在急性期兴奋性氨基酸(EAAs)Asp、Glu和抑制性氨基酸(IAAs)Gly参与了格林巴利综合征的发病过程。
Conclusion : Asp , Glu , and Gly are involved in the acute phase of Guillain_Barre syndrome .
-
目的:探讨兴奋性氨基酸、N甲基D天冬氨酸受体(NMDAR)在大鼠百日咳杆菌脑损伤中的变化及作用机制。
Objective : To explore changes and mechanism of EAAs and its specific N-methyl-D-aspartate receptor ( NMDAR ) on bordetella pertussis brain injury in rats .
-
NMDA受体是兴奋性氨基酸谷氨酸(Glu)的特异性受体,属配体门控离子通道,是由不同的亚单位组成。
The NMDA ( N methyl D aspartate ) receptor is a ligand gated subtype of ionotropic glutamate receptors , comprising different subunits .
-
SHR突触下致密小体可能与兴奋性氨基酸合成增加、谷氨酸受体激活以及兴奋性冲动增加有关。
Subsynaptic dense bodies might associate with the activity of glutamate receptors , the increase of excitatory neurotransmitter and the excitatory afferent input .
-
同时,TFP也可显著地抑制缺氧所致脑片孵育液中兴奋性氨基酸含量的增加(P0.05)。
TFP can also markedly inhibit the increase of the excitatory amino acid ( EAAS ) in the culture medium of brain slices during hypoxia ( P0.05 ) .
-
结论:DSS具有明显的神经保护作用,其机制可能与改善能量代谢、抗氧化及拮抗兴奋性氨基酸等有关。
Conclusion : DSS has the remarkable neuroprotective effect , which might be connected with the improvement of energy metabolism , inhibition of oxidation and excitory amino acid .
-
VD的具体发病机制目前尚不完全清楚,目前研究认为,VD与兴奋性氨基酸毒性、炎症反应、自由基、胆碱酯酶和细胞凋亡、线粒体功能障碍等学说有关。
According to current studies , the excitotoxicity , inflammation , free radicals , cholinesterase and apoptosis , mitochondrial dysfunction may be related to VD .
-
目的探讨神经毒素兴奋性氨基酸(EAA)和神经肽在脊髓损伤中的作用。
Objective To elucidate the effect of neurotoxin , excitatory amino acid and neuropeptide on spinal cord injury post trauma .
-
目的探明脊髓伤后脊髓组织中一氧化氮合酶(NOS)活性变化与兴奋性氨基酸(EAA)释放间的关系。
Objective In order to investigate the relationship between nitric oxide ( NO ) and excitatory amino acid ( EAA ) in spinal cord tissue .
-
目的:SS研究大鼠脊髓压迫损伤减压后钙离子和兴奋性氨基酸变化及其与神经功能恢复的关系。
AIM : To study the changing contents of excitatory amino acids and calcium ions and their relation to neuronal function recovery after decompression of spinal cord compression injury in rats .
-
目的目前对兴奋性氨基酸(EAA)和抑制性氨基酸(IAA)的临床研究较少,从临床方面探讨EAA,IAA在脑梗塞发展过程中的作用可为今后临床深人研究提供一定的参考资料。
Objection Our study was to discuss the effect of EAA and IAA in cerebral infartion from clinic and to afford reference for further investigation .
-
高效液相色谱结果显示:骨癌痛组大鼠RVM区和脊髓兴奋性氨基酸谷氨酸含量均显著升高,与对照组相比差异有统计学意义(P<0.05)。
The results of high performance liquid chromatography showed that the concentration of Glutamate in RVM and spinal cord were significantly higher than the other control groups ( P0.05 ) . 3 .
-
目的:观察丙戊酸(valproate,VPA)对戊四氮(pentylenetetrazol,PTZ)点燃的自由活动大鼠海马胞外兴奋性氨基酸类神经递质动态释放过程的影响。
Aim : To study the dynamic release of amino acid transmitters induced by valproate in pentylenetetrazol-kindled freely moving rats ' hippocampus .
-
FK506对大鼠脑液压伤后血浆一氧化氮合酶、一氧化氮、内皮素和脑组织兴奋性氨基酸水平的影响
The Effect of FK506 on Plasm Levels of Nitricoxide Synthase , Nitrogen Monoxide , Endothelins and Tissue Excitatory Amino Acids Following Brain Fluid Percussion Injury in Rats
-
目的探讨在大鼠脑发育期补充必需脂肪酸兴奋性氨基酸(EFA)对脑组织中EAA含量的影响。
Objective To investigate the effects of essential fatty acids ( EFA ) on the excitatory amino acid in tissues of rat brains .
-
结果同A组比较,B组脊髓组织兴奋性氨基酸含量早期显著增高(P<005),而后期无显著性差异(P>005)。
[ HT5H ] Results [ HT5SS ] Compared with group A , the content of EAA was significantly higher than that of group B at early stage ( P < 0 05 ), but there was no obviously difference at later stage ( P > 0 05 );