凋亡体

Cyto-C、Apaf-1与caspase-9前体组成凋亡体（apotosome），活化的caspase-9进一步诱导效应caspase如caspase-3的活化引起细胞凋亡。

Cyto-C , Apaf-1 and caspase-9 precursor form a " apoptotic bodies " ( apotosome ), activated caspase-9 and further induction of caspase such as caspase-3 activation caused apoptosis .

结论：活性氧中间产物是TNF诱导细胞凋亡的中介体之一。

Conclusion : Reactive oxygen intermediates was a mediator of apoptosis induced by TNF .

背景人体细胞内主要运用泛素-蛋白酶体（Ubiquitin-proteasomepathway，UPP）的蛋白水解酶体系调控细胞的增殖、分化和凋亡，所以蛋白酶体的活性状态对维持细胞的正常功能起重要作用。

Backgroud : Ubiquitin-proteasome pathway is the major proteolytic system in the mammal cells , involved in the regulation of cell proliferation , differentiation and apoptosis . The activation of the proteasome is curial for maintaining cell survival and function .

细胞凋亡在非甾体类抗炎药物所致胃黏膜损伤中的作用及机制研究

Studies on the Role and Mechanisms of Apoptosis in Nonsteroidal Anti-inflammatory Drugs-induced Gastric Mucosal Damage

采用流式细胞仪检测原代和系列传代肿瘤样本中细胞周期/凋亡分布以及倍体数。

The cell cycle distribution , apoptosis and ploidy of the original tumor and the transplants were studied with flow cytometry .

TUNEL染色所见阳性凋亡细胞，其凋亡特征为胞体缩小、核固缩、核碎裂、凋亡小体形成。

The apoptotic features of apoptotic positive cells found in TUNEL staining were shrinking cell body , nuclear pyrosis , nuclear fragmentation and the formation apoptotic body .