戒断反应

和厚朴酚与厚朴酚在缓解大鼠吗啡戒断反应中对β-内啡肽的影响

Effect of honokiol and magnolol on β - endorphin in relievable morphine withdrawal symptoms in rats

β-内啡肽在褪黑素缓解吗啡戒断反应中的作用

The Role of β - Endorphin in Relievable Effect of Melatonin On Morphine Withdrawal Symptoms in Rats

曲马朵急性戒断反应诱导小鼠大脑皮层μ受体mRNA表达增加

Acute tramadol abstinence enhances the expression of mu receptor mRNA in cerebral cortex of mice

MT可抑制由戒断反应引起的血浆和脑组织中NO含量的升高。

The increased NO content in plasma and brain tissue in morphine dependent mice was reduced by ig MT.

5-HT（1A）受体激动剂乌拉地尔对小鼠吗啡戒断反应与血浆及脑内NO含量的影响

Effect of Urapidil on Morphine Withdrawal Syndromes in Mice Changes of NO in Plasma and Brain Tissue

结论脊髓水平NO参与吗啡依赖和戒断反应，ERK信号通路可能介导NO的上述作用。

Conclusion The spinal NO involves in morphine dependence and withdrawal , and its role may be mediated by ERK signal pathway .

急性给予一定剂量的MLT可减弱吗啡依赖GPI及小鼠的戒断反应；

MLT ( administered acutly ) can attenuate the withdrawl syndromes of morphine-dependence on the GPI or mice .

结论：杏仁核点燃模型对纳洛酮等药物的反应及NAc脑区DA及其代谢产物的变化都与戒断反应的表现一致。

Conclusion : The response of amygdala kindling model to naloxone and other agents and the change of the content of DA and its metabolites are consistent with withdrawal syndromes .

目的探讨不同5HT受体在吗啡戒断反应中的作用。

Objective To study the effects of different 5 HT receptors on morphine withdrawal syndromes .

结论抗抑郁药有助于中学生伴抑郁的IAD临床矫治，尤其在减轻戒断反应、改善人际与健康等方面具有显著作用。

Conclusions Antidepressant is an effective method for treating middle school students with depressant IAD , especially in mitigating withdrawal reaction , ameliorating personal relationship and health and maintaining therapy .

结论：脊髓和脊髓上中枢神经元PI-3K信号通路均参与吗啡依赖的形成及戒断反应的表达。

Conclusion : Both spinal and supraspinal neuronal Phosphoinositide 3-kinase ( PI3K ) pathway played important role in morphine dependent and naloxone-precipitated withdrawal response in mice .

于末次注射吗啡后6h观察各组小鼠30min内跳跃反应次数、戒断反应前后1h内跳跃潜伏期、直立、躯体拉伸、体质量丧失量及腹泻等症状。

Six hours after the last injection , the jumping response times in 30 minutes , jumping latency in 1 hour before and after withdrawal reaction , straight , body stretch , loss of body mass , diarrhea and other symptoms were observed .

本文报告酒精戒断反应一例。

This paper reports a case of alcohol withdrawal reaction .

莫索尼定对吗啡成瘾小鼠戒断反应的影响

Effects of moxonidine on withdrawal response in morphine dependent mice

结论东莨菪碱抑制乙酰胆碱的释放，可以减轻吗啡戒断反应；

Conclusion Scopolamine could relieve morphine withdrawal syndrome by inhibiting release of acetylcholine .

氯氮平戒断反应发生率为ll.ll%。

This more severe reaction fol-lowing clozapine withdrawal had an incidence rate of ll .

结果表明本品能减轻吗啡依赖性小鼠的戒断反应。

The results showed that it could abate the abstinence reaction of morphin-dependent mouse .

脊髓水平细胞外信号调节激酶激活参与吗啡依赖的形成及戒断反应的表达

Activation of the spinal extracellular signal-regulated kinase is involved in morphine dependence and naloxone-precipitated withdrawal response

目的：探讨吗啡戒断反应对血管反应性及其细胞内信号转导的影响。

AIM : To probe the changes of vascular responsiveness and intracellular signaling during opiate withdrawal syndrome .

目的探讨丙戊酸钠对酒精戒断反应的临床疗效及副反应。

Objective To investigate the clinical efficacy and side effects of sodium valproate in the treatment of alcohol withdrawal reaction .

目的观察褪黑激素对小鼠吗啡戒断反应及血清单胺类递质的影响。

Objective To observe the inhibitory effect of melatonin on morphine withdrawal syndromes and serum monoamines in morphine dependent mice .

结果（1）给大鼠灌胃50%酒精8周可观察到戒断反应；

Results : ( 1 ) Withdrawal can be observed in the given 50 % alcohol group at the eighth week ;

生物药剂因素，如浓茶、咖啡、兴奋剂、戒断反应等，或是其他神经精神疾病所引起。

There were many reasons induced insomnia such as physical body , environmental factors , biomedical drugs and other nervous psychosis .

结论褪黑激素可抑制小鼠吗啡戒断反应并降低由戒断反应引起的血浆和脑组织中NO含量的升高。

CONCLUSION The physical withdrawal syndromes and the content of NO in plasma and brain tissue in morphine dependent mice are inhibited by MT.

慢性吗啡处理可能引起所有神经元受体改变，近来有研究表明海马在耐受、依赖和戒断反应中有重要作用。

Although chronic application of opiates is expected to produce changes in all neurons expressing the appropriate receptors , recent studies have implicated the hippocampus is playing a central role in opiate tolerance , dependence , and withdrawal .

近些年来，随着医学不断发展，和厚朴酚的药理作用越来越方泛，研究表明和厚朴酚还具有抗炎、抗菌、抗氧化、抗肿瘤、抑制吗啡戒断反应等。

In recent years , with the continuous development of medicine , the pharmacological effects of honokiol more square pan , studies have shown that honokiol also has anti-inflammatory , antibacterial , antioxidant , anti-tumor , inhibition of morphine withdrawal reactions .

目的：研究粉防己碱（Tet）和尼莫地平（Nim）对吗啡在离体豚鼠回肠中戒断性反应的影响。

AIM : To evaluate the effects of tetrandrine ( Tet ) and nimodipine ( Nim ) on the morphine ( Mor ) withdrawal response in the isolated guinea pig ileum .

小鼠吗啡依赖纳洛酮催促戒断跳跃反应模型的建立

A Stable Model of Naloxone-induced Withdrawal Jumps in Morphine-dependent Experimental Mice

动物研究表明，摄入糖分会导致暴饮暴食、戒断不良反应和内心产生极度渴望。

Animal studies show sugar consumption causes bingeing , withdrawal and craving .

目的建立稳定的小鼠吗啡依赖纳洛酮催促戒断跳跃反应模型。

Objective To establish a stable model of naloxone-induced withdrawal jumps in morphine dependent mice .