治疗指数

治疗指数（TI）分别为：5.8、2.03。

The therapeutic index ( TI ) is 5.8 and 2.03 respectively .

通过观察细胞病变效应，用噻唑蓝（MTT）比色法检测细胞存活率，以确定该药物治疗指数。

By means of observing cytopathic effect and adopting MTT colorimetric assay for cell survival rate , their therapeutic index was calculated .

治疗指数（TI）分别为1100和100。

The experimental TI was 1100 and 100 respectively .

灯盏花素改善肿瘤化疗药物对小鼠lewis肺癌的治疗指数

Therapeutic index improvement of chemotherapeutic agents in mice bearing lewis lung cancer with Breviscapine

ml-1，治疗指数（TI）为16。

The therapy index ( TI ) is 16 .

对HBsAg治疗指数大于80.32，对HBeAg治疗指数为6.18。

The treatment index on HBsAg positives was > 80.32 and 6.18 on HBeAg positives .

然而，CsA具有治疗指数窄、药动学和药效学个体差异大的特点。

However , CsA is characterized by a narrow therapeutic index and large interindividual difference in both pharmacokinetics and pharmacodynamics .

但是RPM也存在自身毒性作用大，吸收限制、亲水性差，对pH敏感和治疗指数偏低，生物应用受限于赋形剂、稳定性等药理学缺点。

However , RPM also has such pharmacological defects as toxic effect , restricted absorption , poor hydrophilicity , restricted biological application by excipient and stability , sensitivity to pH and low treatment index .

结果：海鞘乙醇提取物对HBsAg、HBeAg的分泌均有较明显的抑制作用，对细胞的毒性低，其治疗指数均在10以上。

Results The results showed that the ethanol extract from Styela plicata has significant inhibitory effect on HBsAg and HBeAg expression , and has very low toxicity to the cells .

环孢素A（CyclosporineA，CsA）是移植术后常用的免疫抑制剂，由于其治疗指数低，临床应用时要求进行血药浓度监测。

Cyclosporine A ( CsA ) has been the mainstay of immunosuppressive therapy for more than 20 years , as a drug with a low therapeutic index , requires individualized monitoring of blood concentration .

LY294002与塞莱昔布、顺铂及多西紫杉醇的协同治疗指数均小于1，具有协同治疗作用。

LY294002 had synergistic effects with celecoxib , DDP , and docetaxel ( combination index < 1 );

结果苦碟子对呼吸道流感病毒H3N2、合胞病毒（RSV）和腺病毒（ADV-3）的治疗指数分别为10,32和16。

Results TI of respiratory influenzal virus H_3N_2 , respiratory syncytial virus ( RSV ) and adenovirus ⅲ( ADV-3 ) was 10,32 and 16 respectively .

结论：黄芪总多糖对HSV2333株的治疗指数为ACV的3.7,2.7,3.3倍，值得开发利用。

Conclusion : The treatment index of PSA for HSV 2 333 strain is 3.7 , 2.7 , 3.3 fold as that of ACV , respectively . It is worthy of exploiting .

苯妥英锌腹腔注射的ED（50）和LD（50）分别为9.74和138.1mg/kg，治疗指数与苯妥英钠接近，刺激性比苯妥英钠小。

ED_ ( 50 ) and LD_ ( 50 ) of phenytoin zinc ip were 9.74 and 138.1 mg / kg respectively . The therapeutic index of phenytoin zinc was closed to that of phenytoin sodium , but its irritability was less than that of later .

AT-267和AT-346对肉瘤180的治疗指数（MTD/MED）分别为6.7和13.4。

The chemotherapeutic indices ( MTD / MED ) of AT-267 and AT-346 for sarcoma 180 were about 6 and 13 respectively .

结论：上述合用比对HSV-2333株直接杀灭、增殖抑制、感染阻断的治疗指数（TI）是ACV的726、525、1400倍，是组方时的最佳配比。

Conclusion : The treatment indices ( TI ) of the direct virucidal activity , the inhibition effects on the multiplication and infection of HSV - 2 333 strain of this combination ratio are 726,525,1 400 times of ACV TIs respectively , it is the most excellent combination ratio .

经皮给药系统（TDDS）是药剂学中快速发展的一个领域，在降低不良反应、提高治疗指数和用药顺应性方面具有明显的优势。

In recent years , the transdermal drug delivery systems ( TDDS ) has been developed rapidly in pharmaceutical science . The uttermost advantage of TDDS is to reduce adverse side effects , to enhance therapy index and for the convenience of clinical usage .

不同浓度滴量的新福林眼液对治疗指数的影响

Effects of phenylephrine eyedrops concentration and drop volume on its therapeutic index

疼痛治疗指数显示有60.19%的病人存在疼痛治疗不足；

Pain Management Indexes showed that 60.19 % of patients were under-treated for pain .

相反，对于治疗指数相对狭窄的药物来说，生物利用度的差异就很重要。

In contrast , bioavailability differences are important for a drug with a relatively narrow therapeutic index .

这3种新复方制剂安全指数与治疗指数分别为31.22，0.2240，5.229；

The Safe margine and IE of the three new compound preparations are 31.22 , 0.2240 , 5.229 ;

在降低不良反应、提高治疗指数和用药顺应性方面具有明显的优势。

TDDS are of advantage to reduce adverse side effects and to enhance therapy index and convenience for clinical uses .

许多抗肿瘤药具有治疗指数低的特征，其药代动力学在病人个体间存在较大的差异，而且具有较高毒性。

Most anticancer drugs are characterized by a narrow therapeutic index , wide inter patient variability of pharmacokinetic parameters and high toxicity .

且作为药物载体，可以提高药物治疗指数，降低药物毒副作用、降低药物剂量。

As a drug carrier , they can elevate the therapeutic exponent , reduce their untoward effects , and decrease the dosage of the medicine .

力可立敏对小自鼠、家兔和猫的急性毒性作用此加兰他敏小2&8倍，其治疗指数接近加兰他敏。

In mice , rabbits and cats , galanthamine hydrobromide was 2-8 times more toxic than lycoramine hydrobromide . The therapeutic index of the two alkaloids was similar .

姜黄素联合雷帕霉素对系膜细胞增殖的抑制效果较同浓度单用组强，其协同治疗指数小于1，二者起协同作用。

The inhibition effect of curcumin combine rapamycin on mesangial cell is stronger than the effect of curcumin or rapamycin alone , the combination index of curcumin and rapamycin is below 1 , this indicating they can exert synergic action .

肝靶向给药系统能将药物定向输送到肝脏，减少其全身分布，减少药物给药剂量和次数，提高药物的治疗指数，降低其不良反应，对肝脏疾病的治疗有积极的推动作用。

The hepatic targeting delivery system , a new style drug preparation , could play an activated role of preventing and curing liver disease as it can specifically transport the medicaments to liver , reduce delivery dose and times , elevate the therapeutic exponent and play down the side effects .

结论Steel三联截骨对于治疗髋臼指数为45°左右患儿，是一种安全有效的手术。

Conclusion Steel osteotomy is a safe and effective procedure for the treatment for the children of congenital dislocation of the hip with AI about 45 ° .

口腔正畸治疗需要指数（IOTN）的一致性检验

Consistency test of the index of orthodontic treatment need

社区牙周治疗需要指数

Community periodontal index for treatment needs