破骨细胞

调节破骨细胞分化的RANK特异性基序的再确认

Re-identification of special motif regulating osteoclast differentiation in RANK

雌激素对去卵巢大鼠骨组织中骨保护素、破骨细胞分化因子和巨噬细胞集落刺激因子mRNA表达的影响

Effect of estrogen on osteoprotegerin , osteoclast differentiation factor and macrophage colony stimulating factor mRNA expressions in ovariectomized rat bone tissue

核转录因子κB受体激活剂可能通过新的信号途径调节破骨细胞分化

Osteoclast Differentiation Regulated by Receptor Activator of Nuclear Factor κ B Probably Through A Novel Signaling Pathway

破骨细胞分化因子mRNA在大鼠正畸牙槽骨改建过程中的表达和分布

The expression and distribution pattern of ODF mRNA during orthodontic tooth movement in rats

白介素-6与1,25（OH）2维生素D3联合作用下大鼠骨髓破骨细胞的体外诱导培养

IL-6 and 1,25 ( OH ) _2D_3 combined induces formation of osteoclast in rat bone marrow culture

结果：SHIP在破骨细胞、破牙细胞和恒牙胚釉质层表达阳性。

RESULTS : SHIP positive signals were observed in the osteoclasts , odentoclasts and enamel of permanent tooth germ .

血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF）除促进血管发生等功能以外，还有上调功能性破骨细胞的重要作用。

Vascular endothelial growth factor ( VEGF ) has an ability to induce functional osteoclasts as well as angiogenesis .

1,25（OH）2维生素D3诱导大鼠骨髓单核细胞形成破骨细胞

1,25 ( OH ) _2 Dihydroxyvitamin D_3 Induces the Formation of Osteoclasts from Mononuclear Cells of Rat Marrow

胰酶消化法纯化诱导不同年龄段SD大鼠骨髓破骨细胞的体外培养

Isolation of Bone Marrow-derived Rat Osteoclast-like Cells with the Digestion of Trypsin

结论：leptin抑制体外培养的破骨细胞的分化和骨吸收功能。

Conclusions : Leptin can inhibit osteoclasts formation and bone resorption .

目的检测人乳牙吸收过程中乳牙根部破骨细胞降钙素受体mRNA的表达。

Objective To investigate the expression of calcitonin receptor mRNA in the osteoclasts of the resorbing deciduous teeth .

IL-6对分离培养的兔破骨细胞1型胶原酶mRNA表达的影响

Effect of interleukin-6 on expression of collagenase type 1 mRNA in isolated rabbit osteoclast in vitro

补肾法对IL-1诱导的破骨细胞性骨吸收及破骨细胞MMP-9的影响

The influence of the kidney reinforcing method on IL 1 induced

1,25-（OH）2D3作用下人牙周膜细胞破骨细胞分化因子及破骨细胞发生抑制因子的表达及意义

Effects of 1,25 - ( OH ) _2D_3 stimulation on expression of ODF and OCIF by human periodontal ligament cells

1α，25-（OH）2D3介导成骨细胞影响破骨细胞形成及活化的研究

The Effects of Osteoblasts on Osteoclasts ' Formation and Activation Mediated by 1 α, 25 - ( OH ) _2D_3

大豆异黄酮类药genistein抑制IL-1β的促破骨细胞骨吸收功能

Genistein inhibits the promotive effect of IL-1 β on osteoclastic bone resorption

应用抗酒石酸酸性磷酸酶（TRAP）染色观察体外培养破骨细胞的生存时间

Observation of the survival period of osteoclasts cultivated in vitro with tartrate resistant acid phosphatase ( trap ) staining

取另一侧股骨远端行TRAP染色，观察大鼠股骨远端破骨细胞数量的变化。

The TRAP staining was performed on the distal femur of the other side to detect the number of osteoclast .

氟可影响破骨细胞抗酒石酸酸性磷酸酶（TRAP）的分泌，呈剂量依赖性。

The excretion of tartrate - resistant acid phosphatase ( TRAP ) was affected by fluorine , presenting dose dependence .

结果在人乳牙吸收面有多个破骨细胞，破骨细胞TRAP染色阳性并且表达钙素受体mRNA。

Results There were a number of TRAP positive osteoclasts on the root surface which showed the expression of calcitonin receptor mRNA .

原代培养破骨细胞接种在材料表面并培养4h和48h。

Primary cultured osteoclasts were incubated for 4h and 48h on samples .

TNF-α还能刺激破骨细胞释放前列腺素E（PGE），引起破骨细胞性骨吸收。

TNF-a can also stimulate osteoclast release PGE ( PGE , prostaglandinE ) which can induce osteoclastic bone resorption .

结果皮质骨内层可培养出多核、体积大、抗酒石酸酸性磷酸酶（TRAP）染色阳性的破骨细胞，淫羊藿提取物对皮质骨来源的破骨细胞没有明显影响。

Results Large multinucleated TRAP-positive osteoclasts from cortical bone were cultured . No obvious effect of icaritin on mature osteoclast was observed .

白介素6（Interleukin-6，IL-6）是参与破骨细胞的分化及功能的一种多效细胞因子。

Interleukin-6 ( IL-6 ) is a pleiotropic cytokine that is involved in osteoclast differentiation and function .

目的观察氟对大鼠破骨细胞（Osteoclast，OC）形成的骨吸收陷窝的影响。

Objective To study the effect of fluoride on resorption pit of osteoclast .

结论：IL-1β的刺激骨吸收作用由成骨细胞所介导，而非直接作用于破骨细胞。

Conclusions : The stimulating effects of IL-1 β on bone resorption were mediated by osteoblasts rather than osteoclasts .

结果：TRAP（+）破骨细胞在牙移动第3、5和7天时数量明显增多；

RESULTS : Result show that the TRAP-positive cells were markedly induced at the compression side at 3,5 and 7 days after tooth movement .

破骨细胞酶组化标记和计数统计显示，TRAP阳性细胞数量在牙移动第3、5和7天时与对照组比较有显著性差异；

Result show that TRAP-positive mononucleated and multinucleated cells were markedly induced at the compression side at 3 , 5 , and 7 days .

破骨细胞分化因子和护骨素mRNA在OVX小鼠骨组织的相对表达

The relative expression of receptor activator of nuclear factor-kappa B ligand and osteoprotegerin mRNA in bone tissue in ovariectomized mice

分别用抗酒石酸酸性磷酸酶（TRAP）染色法和骨小坑染色法检测TRAP阳性的破骨细胞量及破骨细胞功能。

TRAP positive multinuclear cells were measured by tartrate-resistant acid phosphatase ( TRAP ) staining and the function of osteoclast was detected by pit staining .