离子通道蛋白
- 名ion channel protein
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根据克隆的野桑蚕钠离子通道蛋白基因序列和家蚕基因组序列,设计引物,采用PCR方法,克隆到3段野桑蚕基因组序列。
According to the sequences of the cloned sodium channel protein genes in Bombyx mandarina and Bombyx mori genome , three Bombyx mandarina genome sequences were cloned by PCR .
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拟除虫菊酯的作用靶标是神经轴突上的钠离子通道蛋白(sodiumchannelprotein),而细胞色素P450第九家族的多个基因与昆虫对拟除虫菊酯抗性有关。
Action drone of pyrethroid is sodium channel protein located in nerve axone , while several genes of the ninth cytochrome P450 family are related to resistance to pyrethroid in insects .
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内含肽介导的氯离子通道蛋白CFTR的反式剪接
Intein-mediated Trans-splicing of Chloride Ion Channel CFTR
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介绍近年来临床主要应用的2类抗流感病毒药物:M2离子通道蛋白抑制剂和神经氨酸酶抑制剂的作用机制、临床应用特点及不良反应,并简要介绍了其他一些在我国常用的抗流感病毒药物。
M2 protein inhibitors and neuraminidase inhibitors are the two main anti-influenza drugs available in clinical use . In this paper , their mechanism of action , clinical efficacy , adverse reactions as well as other anti-influenza drugs commonly used in China are introduced .
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Na+/H+交换器-1(NHE-1)是调节白血病细胞pHi最主要的离子通道蛋白,它通过介导细胞内H+和细胞外Na+1:1交换调节pHi,因此,NHE-1的表达量及活性直接影响pHi的变化。
Sodium hydrogen exchanger isoform-1 ( NHE-1 ) is the main ionic channel protein to regulate pHi of leukemia cells by 1:1 efflux of H + and influx of Na + ions . The expression and activity of NHE-1 directly regulate pHi of leukemia cells .
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氯离子通道蛋白1的细胞转染定位
Localization of chloride intracellular channel protein 1 in transfected cell
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酵母双杂交技术筛选胞内氯离子通道蛋白1结合蛋白
Screening of chloride intracellular channel 1 binding proteins by yeast two-hybrid system
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酸敏感离子通道蛋白与组织型激肽释放酶相互作用的研究
Interaction between Acid-Sensing Ion Channels and Tissue Kallikrein
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现代药理学研究显示,虎杖苷具有改善血液流变学、抗血栓的形成、抗氧化、调节一氧化氮、影响离子通道和蛋白激酶等多种活性作用。
Modern pharmacological studies have demonstrated that polydatin has multiple biological activities such as improve blood rheology , anti-thrombus formation , anti-oxidation , regulate nitric oxide , affecting ion channels and protein kinase .
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根据预测功能其中包括一些重要的功能基因,包括信号蛋白、离子通道相关蛋白、参与激素合成酶类、分化相关蛋白、重要的转录因子及翻译启始因子等。
Comparison of homology and analysis of motif or domain showed that some genes may be important functional genes , such as those coding signaling proteins , proteins associated with ion channel , enzymes involved in hormone production , important transcription factors , translation initiation factors , etc.
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并且大量研究结果发现,神经系统中,部分甾体激素类物质可以直接作用于一些细胞膜表面配体门控离子通道或G蛋白偶联受体,从而在数毫秒至数秒内即可改变神经元兴奋性。
Considerable evidence has emerged that , during a millisecond to second time window , some steroids alter neuronal excitability via the cell surface through the interaction with specific neurotransmitter receptors or G-protein coupled receptors .
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尤其在新药研发的过程中,几类蛋白诸如酶,离子通道,G蛋白偶联受体(GPCR)和核受体代表了当前药物靶标的绝大多数。
In particular , several classes of proteins such as enzymes , ion channels , G-protein-coupled receptors ( GPCR ) and nuclear receptors represent the vast majority of current drug targets for new drug development .
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钾离子通道相互作用蛋白与Kv4
Kv Channel Interacting Proteins and Kv 4
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缺血预适应的信号转导途径涉及触发物质(内源性活性物质),中介物质(蛋白激酶)和效应物质(离子通道和保护蛋白)。
The signal transduction pathways of ischemic preconditioning involve triggers ( endogenous active substances ), mediators ( protein kinases ) and effectors ( ionic channels and protective proteins ) .
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这些基因涉及基因转录调控、信号转导、离子通道、突触蛋白、钙结合蛋白、氧化还原反应等。
Genes that changed over two times involved in signal transduction , gene transcription regulation , ion channels , synaptic proteins , calcium binding proteins , oxidation reduction , et al .
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差异表达基因涉及离子通道和运输蛋白、细胞周期蛋白类、细胞骨架和运动、细胞受体、细胞信号和传递蛋白、代谢、免疫相关等多个方面。
The differently expressed genes were functionally related with ion channels and transport proteins , cyclins , cytoskeleton , cell receptors , cell signal transduction , metabolism , immunity , and so forth .
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氯离子通道ClC-2及ClC-3蛋白在鼻息肉发病中的作用
Expressions of chloride channel ClC-2 and ClC-3 in human nasal polyps
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目的:探讨氯离子通道ClC2和ClC3蛋白与鼻息肉形成的可能关系。
Objective : To investigate the role of chloride channel ClC-2 and ClC-3 in human nasal polyps .