糖基化

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  • glycosylation
糖基化糖基化
  1. 晚期糖基化终末产物和蛋白激酶C对糖尿病大鼠肾脏的影响

    Relationship among advanced glycosylation end products , protein kinase C and renal

  2. 糖基化终产物对肾间质成纤维细胞DNA损伤的影响

    Advanced glycosylation end products induce DNA damage in NRK-49F cells

  3. 目的鉴定γB-晶体蛋白非酶糖基化位点。

    Objective To identify the glycation sites of lens γ B-crystallin .

  4. 能够抑制糖基化终末产物(AGE)的产生,以减少其毒性作用;

    Restrain advanced glycation end products ( AGE ) and alleviate toxicity ;

  5. N-烷基嘧啶DNA糖基化酶腺病毒提高人骨肉瘤化疗敏感性的研究

    Effect of adenoviral N-methylpurine DNA glycosylase overexpression on chemosensitivity of human osteosarcoma cells

  6. C反应蛋白增加人内皮细胞糖基化终产物受体表达

    C Reactive Protein Increases the Expression of Receptor for Advanced Glycation End-products in Human Endothelial Cells

  7. Cthrc1的激活状态是一种锚在细胞膜表面的一种N末端糖基化的三聚体。

    And its active form is an N-glycosylated trimer anchored on the cell surface .

  8. 序列中有N一糖基化位点,蛋白激酶C磷酸化位点和酪蛋白激酶11磷酸化位点;

    The sequence has N-glycosylation site , Protein kinase C phosphorylation site and Casein kinase II phosphorylation site .

  9. 目的建立小分子糖基化终产物肽(AGEP)的一种检测方法。

    Objective To establish an analyzing approach for low molecular weight advanced glycosylation end products peptide ( AGE P ) .

  10. N糖基化抑制对脑胶质瘤细胞株SWO-38N-GSLs合成的影响

    Study on the Effects of N-glycosylation Inhibition on the Expression of N-GSLs in Glioma Cell Line SWO-38

  11. 应用糖苷酶酶切和特征性的天冬酰胺序列子的检测发现了39个蛋白中的48个潜在的N型糖基化位点。

    Using the characteristic asparagine sequon detection , we found 48 possible N-glycosylation sites in 39 proteins .

  12. 它们都含有高百分比的脯氨酸(P)、丝氨酸(S)和苏氨酸(T),含有相当数量的位于胞外区的O-连接糖基化位点。

    These predicted G proteins had a relatively high contents of proline , serine , threonine residues and O-linked glycosylation sites .

  13. 研究表明:AD脑神经丝蛋白的糖基化修饰水平降低,伴随着磷酸化修饰水平增加,其机制目前尚不清楚。

    The study demonstrated that O-Glycosylation of neurofilaments decreased and phosphorylation increased in AD brains .

  14. 作者解释道,升高的皮肤晚期糖基化终末产物(AGE)是糖尿病的生物标志物。

    An elevated level of skin advanced glycation end products ( AGE ) is a biomarker of diabetes , the authors explain .

  15. 竞争性RT-PCR法定量检测糖基化磷脂酰肌醇特异性磷脂酶D基因的表达

    Competitive RT - PCR assay for quantification of GPI-PLD gene expression

  16. 结论吡哆胺对体外晚期糖基化反应和AGEs形成有明显抑制作用。

    Conclusion pyridoxamine displayed significantly inhibitory effect on advanced glycation reaction and AGEs formation in vitro .

  17. 结论成功地构建了t-PAcDNA糖基化位点突变体。

    CONCLUSIONS The mutants of t-PA cDNA clone at glycosylation sites are successfully constructed .

  18. 上述功能的发挥,很大程度上依赖于其胞外区片段(extracellulardomain,ed)的表达及糖基化修饰作用。

    The exertion of the function mostly depend on the expression and glycosylation of its extracellular domain .

  19. 脑缺血后晚期糖基化终产物受体(RAGE)的表达

    Expression of Advanced Glycation Receptor Products ( RAGE ) after Cerebral Ischemia

  20. S蛋白由1256个氨基酸组成,有23个潜在的糖基化位点,其N端和C端相对保守。

    SARS-CoV Spike protein , which has 23 pieces larvaceous glycosylation sit , consists of 1256 amino acid . Its N-terminals and C-terminals is corresponding conservative .

  21. 黄芪对IgA肾病患者免疫球蛋白分子糖基化异常的调节作用

    The Effect of Astragalus Membranaceus on Galactosylation of IgA in IgA Nephropathy Patients

  22. 而最近研究发现,晚期糖基化终产物受体(receptorforadvancedglycationendproducts,RAGE)与前列腺癌也密切相关。

    Recent studies have found that the receptor for advanced glycation end products ( RAGE ) is closely related to prostate cancer .

  23. 先天性Ia型糖基化障碍患者的骨骼发育不良和脊髓病

    Skeletal dysplasia and myelopathy in congenital disorder of glycosylation type Ia

  24. 结论:糖基化终产物可促进大鼠主动脉平滑肌细胞MMP-2的表达。

    Conclusion : Expression of MMP-2 of VSMCs can be promoted by AGEs .

  25. 雷公藤内酯醇对IgA肾病大鼠血清IgA异常糖基化的影响

    Effects of triptolide on abnormal glycosylation of serum IgA in rats with IgA nephropathy

  26. 糖基化低密度脂蛋白增强人外周血单核巨噬细胞的Sis基因表达

    Enhancement of sis Gene Expression in Human Monocyte-macrophages by Glycosylated Low Density Lipoprotein

  27. SDS-PAGE结果和FT-IR分析结果均证明了糖基化接枝反应的发生。

    The results of SDS-PAGE and infrared analysis proved that the glycosylation grafting reaction happened .

  28. CGMP具有不同的种类,主要是由于其不同的糖基化和磷酸化结构。

    CGMP is heterogeneous due to different glycosylation or phosphorylation .

  29. GSH、LA与蛋白糖基化反应体系共育后AGEs含量均显著下降,GSH强于LA的作用,但对体系内羰基含量无明显影响;

    AGEs content was significantly decreased after protein glycation system were incubated with GSH and LA for 8 weeks .

  30. PAI-1糖基化位点突变体的构建及其在哺乳动物细胞中表达

    Construction of mutant glycosylation sites of PAI-1 and expression in mammalian cells