肿瘤免疫

肿瘤抗原与肿瘤免疫

Identified Analysis of Tumor Antigen and Tumor Immunization

肿瘤细胞凋亡增强是DC肿瘤免疫的可能机制。

The mechanism underlying tumor immunization resulted from DCs might be enhanced in apoptosis of tumor cells .

DC的这一固有免疫功能在肿瘤免疫治疗中具有重要的意义。

The unique innate immune functions of DCs are crucial in tumor immunotherapy .

DNA疫苗与肿瘤免疫治疗

DNA vaccines and cancer immunotherapy

Th1/Th2细胞的免疫功能变化与抗肿瘤免疫

Transformation of Immune Function and Antitumor Immunology of Th_1 / Th_2 Cell

结论DC瘤苗以其安全、有效、易行的特点，将会在肿瘤免疫治疗中具有良好的应用前景。

Conclusion DC vaccine is promising in tumor immunotherapy owing to its safety , efficiency and convenience .

结论SP2/0细胞膜抗原负载DC能诱导明显的特异性抗肿瘤免疫应答。

Conclusion SP2 / 0 cellular membrane antigen-loaded DC can elicit potent specific antitumor immune response in vitro .

可溶性TNF受体基因修饰的树突状细胞诱导抗原特异性肿瘤免疫耐受的机理

Soluble TNF - α Receptor Gene Modified Dendritic Cells Induce Antigen Specific Tolerance to Tumor-Isograft

研究显示，DC广泛参与机体免疫、炎症、肿瘤免疫、移植排斥、应急反应等生理及病理过程。

DC participate immunization , inflammation , tumor immunity , graft rejection , emergency response and other physiological and pathological processes .

膀胱癌IL-2基因瘤苗诱导的抗肿瘤免疫反应

Induction of anti tumor immunity by IL 2 gene transferred bladder cancer vaccine

Poly（I：C）在肿瘤免疫治疗中的作用已被广泛论证。

The effect of poly ( I : C ) in tumor immune therapy have been well demonstrated .

树突状细胞（DC）是专职的抗原递呈细胞（APC），是唯一能激活纯真T细胞的APC，在肿瘤免疫治疗中起重要作用。

Dendritic cells ( DCs ) are a specialized system of antigen - presenting cells .

CD4~+CD（25）~+调节性T细胞在肿瘤免疫治疗中的价值及应用前景

The Prospects of the usage of CD_4 ~ + CD_ ( 25 ) ~ + regulatory T cells in cancer immunotherapy

树突状细胞（DC）作为功能最为强大的抗原呈递细胞，对肿瘤免疫起着关键的启动作用。

As the potent professional antigen present cell , dendritic cells ( DC ) play an important role in the initiation for anti-tumor immunity .

MHCⅡ类基因转染对肿瘤免疫的影响

Effects of MHC class ⅱ gene transfection on tumor immunogenicity

异种同源MMP-2细胞疫苗抗肿瘤免疫研究

Immunotherapy of Cancer with Tumor Cell Vaccine Based on the Chicken Homologous Matrix Metalloproteinase-2

FasL表达在肝癌肿瘤免疫逃避中的意义

Significance of the Expression of FasL in Tumor Immune Evasion of Liver Neoplasms

IL-2基因修饰增强白血病抗原冲击的树突状细胞诱导的抗肿瘤免疫反应

Induction of potent antitumor immune response of leukemia antigen pulsed dendritic cells by IL 2 gene modification

目的研究荷瘤小鼠骨髓来源的树突状细胞（DC）是否具有诱导机体产生抗肿瘤免疫反应的能力，与正常小鼠骨髓来源的DC有无差异。

Objective To investigate whether the dendritic cells ( DCs ) from the marrow of tumor bearing mouse has the potent capacity of inducing antitumor immunity .

近年来随着人们了解的深入，基于DC的肿瘤免疫治疗方法越来越受关注。

With the intensive understanding to the biological behaviors of DC , people pay more and more attention to the role of DC in cancer immune therapy .

目的观察树突状细胞（DC）从丝裂霉素诱导的凋亡胆管癌细胞获取抗原后，抗肿瘤免疫应答及对胆管癌细胞的特异性免疫杀伤效果。

Objective To investigate the anti-tumor immune response of dendritic cells ( DCs ) acquiring antigens from apoptotic cholangiocarcinoma cells and their therapeutic effects on cholangiocarcinoma cells .

结论：无血清DCs专用培养基可以在体外快速培养临床级DCs，为肿瘤免疫治疗奠定基础。

Conclusion : Clinical grade DCs can be cultured rapidly in serum-free DC medium and can be used in tumor immunotherapy .

膀胱移行细胞癌组织Fas/Fasl和c-myc表达与肿瘤免疫逃逸相关性研究

Relationship between expressions of Fas / Fasl and c-myc in BTCC and immune evasion of tumor

IL-12协同B7-1增强实验小鼠的抗肿瘤免疫

IL-12 Synergizes B7-1 Enhance the Antitumor Immunity in Experimental Mice

FasL的表达异常与膀胱癌组织类型及病理分级关系不密切，其所致的肿瘤免疫逃避作用可能是恶性肿瘤发展的基本原因之一。

Tumor escape induced by FasL might be one of the basic reasons in progression of neoplasm .

目的研究转染Survivin的树突状细胞（DC）在体外诱导高效而特异的抗消化道肿瘤免疫效应。

Objective To study the effective and specific anti alimentary tract tumor immunological effects induced in vitro by dendritic cells transfected with survivin gene .

结论He-Ne激光具有促进HeLa细胞调亡信号形成，从而发挥抗肿瘤免疫效应。

Conclusions He-Ne laser can induce the apoptotic signal of HeLa lines and inhibit the growth of the tumor .

NK细胞在肿瘤免疫中形成第一道防线，其在白血病免疫治疗中的作用备受关注。

NK cells form the first line of defense in tumor immune , and is got the attention in leukemia immunotherapy .

GM-CSF被认为是激发特异、持久抗肿瘤免疫的最主要的细胞因子。

GM-CSF is considered the most potent cytokine that induces specific , long-lasting immunity to tumors .

IL-12协同B7-1诱导机体抗肿瘤免疫的实验研究

Study of the induction of anti-cancer immunity effects of interleukin 12 and co-stimulatory molecules B7-1