胰高血糖素

GnRH类似物对大鼠回肠组织胰高血糖素释放的影响

Effect of GnRH analogue on glucagon secretion in rat ileum

腹腔镜胆囊切除术对胰高血糖素和C肽的影响

Influence of laparoscopic cholecystectomy on Glucagon and C - peptide

C液经DEAE&纤维素柱层析分离，其峰Ⅱ为电泳纯胰高血糖素（D）。

Concentrated ( C ) was separated by DEAE - cellulose chromatography column .

急性胰腺炎患者血浆C肽和胰高血糖素的水平及意义

Variety and significance of serum C peptide and glucagon in patients with acute pancreatitis

用胰高血糖素C肽激发试验评估儿童青少年糖尿病患者胰岛功能

Evaluation of β - cell function in children and adolescent diabetics with glucagon-stimulating C-peptide test

胰高血糖素样肽-1对糖尿病小鼠胰岛素原mRNA的影响

Role of glucagon-like peptide-1 on proinsulin mRNA levels in diabetic mouse

糖尿病患者治疗前后血胰岛素C肽和胰高血糖素变化

Changes of Levels of Insulin , C-peptide and Glucagon in Blood of Diabetic patients before and after Treatment

颅脑损伤急性期血清胰岛素、胰高血糖素、C肽及血糖变化及其临床意义

Changes of Serum Insulin , Glucagon , C-peptide , Blood Glucose and Its Clinical Significance after Acute Brain Injury

胰岛包含分泌胰高血糖素的α（A）细胞，分泌胰岛素的β（B）细胞和分泌生长抑素的δ（D）细胞。

The islets contain alpha cells secreting glucagon , beta cells secreting insulin , and delta cells secreting somatostatin .

可分泌性胰高血糖素样肽1融合蛋白cDNA克隆的构建

Construction of cDNA clone of the secretory glucagon-like peptide-1 fusion protein

代谢产物对体外培养新生犊牛肝细胞胰高血糖素受体mRNA丰度的影响

Effects of metabolite on expression of glucagon receptor mRNA in neonatal calf hepatocytes in vitro

结果表明，胰高血糖素N端组氨酸影响其分泌效率。

In addition , it was found that the N-terminal Histidine of glucagon influenced the secretory efficiency of glucagon .

肝病患者胰高血糖素、糖化血红蛋白检测及胰岛素和C肽释放试验的临床意义

Clinical Signification of the C-peptide and Insulin Release Tests and Detection of Glycosylated Hemoglobin and Pancreatic Glucagon in Patients with Liver Diseases

ELISA试剂盒方法测定重组人胰高血糖素类多肽-1（7-36）浓度

Measurement of recombinant human glucagon-like peptide-1 ( 7-36 ) concentration by ELISA kit methods

ChildB级组胰高血糖素水平高于ChildA级组（P<0.05）。

The glucagon level in Child B group was higher than that in Child A group ( P < 0 . 05 ) .

目的：测定急性颅脑损伤患者的血清胰岛素、胰高血糖素、C肽及血糖的含量变化，探讨血清中胰岛素、胰高血糖素、C肽及血糖与颅脑损伤的关系及临床意义。

Objective : To study the relationship between variation of levels of serum insulin , glucagon , c-peptide , blood glucose and acute brain injury .

各组INS，胰高血糖素仅在10天后测量。

INS , glucagons were measured only 10 days later .

结论：成功构建了能够分泌表达胰高血糖素样肽1的融合蛋白的cDNA克隆。

CONCLUSION : The cDNA clone that can secrete and express GLP-1 the fusion protein is successfully constructed .

经TCA沉淀，分子筛与HPLC三步分离，得到纯化的重组胰高血糖素。

The purified recombinant glucagon was obtained by precipitation with TCA , gel filtration and HPLC .

该模型具有中戈满岁咨血糖升高，血清胰高血糖素升高，cAMP升高，胰岛素mRNA表达量下降的特征。

The model has the features of high level of blood glucose serum glucagon cAMP and low transcriptional level of mRNA of insulin .

在获得重组胰高血糖素基因工程菌基础上，利用定点突变技术改造其第21位氨基酸天冬氨酸为丙氨酸，并经DNA测序证明胰高血糖素基因发生了点突变。

Using recombinant glucagon expression system , the 21st aspartic acid was changed to be alanine by means of site directed mutagenesis . Glucagon gene mutation was testified by DNA sequencing .

目的研究胰高血糖素受体（GR）拮抗剂筛选模型的建立。

AIM : To set up the screening model for glucagon receptor ( GR ) antagonist .

~（21）Ala定点突变胰高血糖素及结构与功能变化

Changes of Glucagon Structure and Function by ~ ( 21 ) Ala Site-Directed Mutagenesis

连续2周观察24h尿氮、静息能量消耗（REE）、血浆皮质醇、胰高血糖素、胰岛素、血清TNF。

The investigation of 24 h urine nitrogen , REE , cortisol , glucagon , insulin and TNF lasted two weeks .

胰高血糖素样肽-2处理可使肠粘膜组织DNA和蛋白含量增加，肠绒毛增长、数量增多，糜烂发生不明显。

GLP-2 administration caused increase in DNA and protein content , villus height , and villus number as compared with irradiated control group . Meanwhile , the villus tips were lack of ulceration .

RP-HPLC法测定重组人胰高血糖素类多肽-1（7-36）原料及其制剂的肽含量和有关物质

RP - HPLC Analysis of Recombinant Human Glucagon - like Peptide - 1 ( 7-36 ) and Its Related Substances

空腹血糖，血清胰岛素、胰高血糖素，肝细胞AC、PDE、cAMP为指标。

Serum glucose , serum insulin , plasma glucagon , and liver AC , PDE and cAMP were used as the parameters of therapeutical effects .

结果：测序证实克隆的胰高血糖素样肽1的cDNA与GeneBank提供的序列完全一致；

RESULTS : The sequencing confirmed that clone GLP-1 cDNA was completely consistent to the sequence provided by GeneBank .

近来在动物模型中的研究表明胰高血糖素通过胰高血糖素受体在调节肝脏甘油三酯（TG）中发挥重要作用。

Recent studies in animal models suggest an important role for glucagon acting via the glucagon receptor in regulating hepatic triglyceride ( TG ) secretion .

Tau组C-肽水平显著升高，胰高血糖素显著降低。

The level of c peptide in taurine group increased significantly , the level of glucagon decreased significantly .