蛋白质结构域

蛋白质结构域折叠类型的离散量理论预测

Prediction of Protein Domain Folding Classes

综述了自由能这个经典判据在划分蛋白质结构域、预测RNA二级结构及蛋白质工程等中的应用。

Application of classical free energy criterion in the delineation of domains for a protein , predicting of RNA secondary structure and protein engineering is reviewed .

YEATSdomain作为一个新颖而保守的蛋白质结构域家族在从酵母到人的很多生物中发现。

YEATS domain , as a novel conserved domain family , was discovered in a variety of eukaryotic species ranging from yeast to human .

基于支持向量机的蛋白质结构域预测方法研究

Research on Prediction of Protein Domains Based on Support Vector Machines

人类新基因识别与蛋白质结构域鉴定

Dissertation Identification of Human Novel Genes and Protein Sequence Motifs

基于序列信息的蛋白质结构域预测学习系统

Prediction of Protein Domains from Sequence Information

快速构建蛋白质结构域克隆库的方法

Rapid Method of Constructing Domain Library

参与细胞衰老的蛋白质结构域

Protein Domains Participated in Cell Senescence

我们用改进重现图方法研究它们的序列对称性，发现对称蛋白质结构域有不同的序列对称度。

We applied modified recurrent plot to analyze their sequences and detected the different degrees of sequence symmetries .

对该基因所推导出的氨基酸进行了信号肽剪切位点、蛋白质结构域、高级中英文摘要结构和专一结合糖基化的分析；

The signal cleavage site prediction , advanced structure prediction , blocks ' analysis and sugar-binding sites were analyzed .

基于去折叠自由能的蛋白质结构域划分方法&适用于连续与不连续结构域

A Method for Delineation of Domains in Proteins Based on Refolding Free Energy & Application to Continuous and Discontinuous Domains

作者曾经发展了一种通过计算去折叠自由能划分蛋白质结构域的方法，但该方法只适用于连续双结构域的划分。

Based on the above definition , a method was previously proposed based on refolding free energy to define continuous domains in proteins .

第二部分是关于人17种组织基因表达谱分析的相关生物信息学研究；第三部分为新的蛋白质结构域的鉴定与功能分析。

The second part describes the in silico analysis of gene expression data of 17 human tissues , as well as the third part describes the identification of two novel protein sequence motifs .

通过高度保守的蛋白质结构域搜索，在此区域预测到4条与拟南芥的叶形调控家族基因高度相关的候选序列，为后续研究提供了有益启示。

In this area , we predicted that four candidate sequences which are highly relevant to the gene family regulating leaf morphology in Arabidopsis thaliana through highly conservative protein structure domain search , which provides beneficial enlightenment for follow-up study .

TAT蛋白质转导结构域与SV40启动子特异的三锌指结构融合蛋白的表达与纯化

Expression and Purification of the Fusion Protein of TAT Protein Transduction Domain with a Zinc Finger that Specific to SV40 Promoter

本研究将GS3蛋白质的结构域的功能与水稻种子籽粒大小的自然变异联系了起来。

This study linked the functional domains of the GS3 protein to natural variation of grain size in rice .

利用蛋白质转导结构域（PTDs）可以将与之融合表达的蛋白质直接送入细胞中。

Protein transduction domains ( PTDs ), such as the PTD of TAT , may transduce peptides which fusion expressed with them into cells .

蛋白质的结构域是蛋白质中具有特异结构和独立功能的区域。

Protein domain is a particular protein structure with independent functions .

通过自由能的差别划分蛋白质连续结构域

Delineation of Continuous Domains in Proteins by Differences of Free Energy

最近通过对蛋白质转导结构域的研究已经排除了这一障碍。

Recent studies on protein transduction domains have circumvented this barrier .

一种基于HIV-1TAT蛋白质转导结构域细胞内转导系统的成功改建

Reconstruction of an intracellular transduction system based on HIV-1 TAT protein transduction domain

本论文的工作主要包括两个蛋白质（结构域）的结构和功能的研究。

Our work focuses on the structural and functional studies of two important proteins ( domains ) .

本论文工作的重点是与人类疾病相关的蛋白质的结构域的克隆表达及结构、功能的研究。

This thesis focus on the cloning , expression , purification and structural and functional studies of domains of human disease related proteins .

应用蛋白质转导结构域将大分子蛋白质、核酸、病毒、小分子物质转运到目标细胞内已引起了人们越来越多的关注。

Increasing attention has been directed towards employing protein transduction domains ( PTDs ) to efficiently deliver full length proteins , nucleic acid , viruses and small molecules to cellular targets .

然后，我们利用NMR方法研究了人的MICAL-1蛋白质的CH结构域的溶液结构，并推测了它的可能的功能。

We also study the structure of human MICAL-1 CH domain by NMR , and speculate its potential function .

蛋白质相互作用结构域PDZ结合特性的研究方法

Method for Studying Binding Properties of a Protein-protein Interaction Domain PDZ

本策略通过筛选随机多肽文库鉴定蛋白质相互作用结构域的配体结合特性。

The binding properties of the protein interaction domains were characterized by screening a random peptide library .

在复杂蛋白质中，结构域具有结构与功能组件与遗传单位的作用。

As structural modules , domains may have advantage to compose complex proteins during the process of protein evolution by insertion , deletion and excising .

一些在组织和细胞分化中起重要作用的蛋白质包含锌指结构域。

Some of proteins associated with differentiation and development of cells and tissues contain zinc finger domain .

该框架以新的结果可视化和面向蛋白质数据库搜索的结构域和功能预测的整合为特色。

The framework features novel result visualizations and integration of domain and functional predictions for protein database searches .