阿糖胞苷
- 名Cytarabine;cytosine arabinoside
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方法共72例用HAD(高三尖杉酯碱、阿糖胞苷及柔红霉素)方案进行诱导缓解治疗的原发初治AML患者进入本研究。
Methods 72 cases of new diagnosed de novo AML treated with HAD ( homoharringtonine , cytosine arabinoside and daunorubicin ) regimen were enrolled .
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【目的】探讨细胞色素C(CYTC)对小剂量阿糖胞苷(LD-Ara-c)诱导白血病细胞凋亡的影响。
【 Objective 】 To discuss the role of cytochrome C ( Cyt C ) in leukemia cell apoptosis induced by low-dose cytosine arabinoside ( LD-Ara-c ) .
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细胞色素C对阿糖胞苷诱导白血病细胞凋亡的影响
The Role of Cytochrome C in Leukemia Cell Apoptosis Induced by LD-cytosine Arabinoside
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通过对Ara-C在不同剂量和疗程时抗白血病的机理研究,验证大剂量阿糖胞苷(HD-Arac)治疗血液肿瘤的优越性。
In addition to study the antileukemic mechanism of Ara-C.
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阿糖胞苷诱导HL-60细胞凋亡的研究
Ara c induced apoptosis in human myeloid leukemia cell line HL 60
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α干扰素联合阿糖胞苷对白血病K562细胞的诱导凋亡作用及其机制
Apoptotic Effects and Its Mechanisms on Leukemic K562 Cells Caused by Interferon-alpha Combined with Cytarabine
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尼莫地平加强阿糖胞苷诱导HL-60细胞凋亡的机制研究
Study on the Enhancing Mechanisms of Nimodipine in HL-60 Apoptosis Induced by Cytarabine
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RP-HPLC法测定细胞内三磷酸阿糖胞苷浓度
Determination of Intracellular Ara-CTP Level by RP-HPLC
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香菇多糖协同阿糖胞苷对HL-60白血病细胞增殖力的影响
The Effects of Lentinan Polysaccharide and Ara-c on the Ability of HL-60 Cells Proliferation
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我们此前报道了氯法拉滨与阿糖胞苷联合使用治疗AML的可行性。
We previously reported the feasibility of clofarabine and cytarabine combinations in AML .
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抗HSV1单克隆抗体阿糖胞苷偶联物制备条件的分步优化
Fractional optimization experiment of production condition for anti-HSV_1 monoclonal antibody conjugate and its determination
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氟达拉滨联合阿糖胞苷对HL-60细胞存活率及代谢酶的影响
Effect of fludarabine combined with cytarabine on the viability and metabolic enzymes of HL-60 cells
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RNA能增强高三尖杉酯碱联合小剂量阿糖胞苷对K562细胞增殖的抑制作用。
RNA could intensify the inhibitory effect of homoharringtonine and low-dose of arabinsyl cytosine on the cell proliferation of K562 cells .
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抗分化HL-60/RA和分化敏感HL-60细胞对阿糖胞苷、三尖杉酯碱等抗肿瘤药物细胞毒作用的敏感性比较
Comparison of the Sensitivity of Retinoic Acid Sensitivity of Resistant HL-60 Cell Lines to Several Anti-leukemia Drugs
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小剂量阿糖胞苷(Arac)或三尖杉脂碱(H)化疗18例,CR率22.2%(418)。
Low dose Ara C or harringtonine were given in 16 elderly patients and the CR rate was 22.2 % ( 4 / 18 ) .
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以bcl-2为靶标siRNA-2提高HL-60细胞对阿糖胞苷的敏感性
SiRNA-2 targeting bcl-2 can enhance the drug-sensitivity of HL-60 cells to cytosine arabinoside
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培养第三天加入终浓度为5mg/ml的阿糖胞苷以抑制神经胶质细胞的过度增殖。
At the 3rd day , in order to suppress the proliferation of glial cells , cytarabine was added .
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目的:进一步了解MAC(马法兰、阿糖胞苷和环磷酰胺)预处理方案对白血病患者骨髓移植后内分泌功能的影响。
Objective : To investigate the effect of MAC conditioning regimen on endocrine glands function in leukemia patients after bone marrow transplantation ( BMT ) .
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不同剂量阿糖胞苷的DA方案治疗CD7抗原阳性急性髓系白血病疗效分析
Chemotherapeutic effect of two different doses of cytarabine combined with anthracycline for CD7 positive acute myeloid leukemia
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Bcl-2/Bax比值下降可能是阿糖胞苷诱导HL-60细胞凋亡的主要机制之一。
Decrease of expression ratio of Bcl-2 / Bax proteins may be one of the main mechanisms in HL-60 apoptosis induced by Ara-C.
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预处理方案为全身照射+环磷酰胺(TBI+CTX)或马法兰、阿糖胞苷、CTX和环己亚硝脲(MAC+CCNU)。
Conditioning regimens were TBI + Cy ( total body irradiation + cyclophosphamide ) or MAC + CCNU .
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阿糖胞苷、阿克拉霉素联合G-CSF治疗50例复发急性髓系白血病的临床研究
Low-dose Cytarabine and Aclarubicin in Combination with Granulocyte Colony-Stimulating Factor Priming in 50 Patients with Relapsed Acute Myeloid Leukemia
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大剂量阿糖胞苷在急非淋白血病患儿体内的药物动力学MAG方案对恶性血液病患者造血干细胞动员作用的研究
Mobilization of peripheral blood stem cells with mitoxantrone and high-dose cytarabine chemotherapy and rhG-CSF in patients with hematopoietic malignancies
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阿糖胞苷增强白血病细胞B7分子表达及促进双功能抗体对靶细胞的杀伤
Cytarabine enhances B7 expression on leukemic cells and promotes cytotoxic effect of bispecific antibody against target cells
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小剂量高三尖杉酯碱、阿糖胞苷联合G-CSF治疗急性髓细胞白血病28例临床分析
Low dose of homoharringtonine and cytarabine combined with G-CSF for treatment of acute myelocytic leukemia : report of 28 cases
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诱导治疗主要采用全反式维A酸诱导分化,继以柔红霉素-阿糖胞苷(DA)、三尖杉酯碱-阿糖胞苷(HA)、柏林-法兰克福-慕尼黑(BFM)方案巩固治疗。
The patients were treated with protocol including induction of differentiation with ATRA followed by consolidation therapy with DA , HA or BFM protocol .
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目的探讨小剂量化疗药物〔高三尖杉酯碱(HHar)、阿克拉霉素(ACR)、阿糖胞苷(Ara-c)〕治疗急性白血病(AL)的可能机制。
Objective To explore the possible mechanism of low - dose chemotherapeutic drugs in treating acute leukemia .
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56例接受大剂量阿糖胞苷(HDAraC)强化治疗,其5年EFS率为(47.2±12.9)%。
The 5 year EFS rate of 56 patients received high-dose cytarabine ( HD-Ara-C ) as intensification therapy was ( 47.2 ± 12.9 ) % .
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目的:研究香菇多糖协同阿糖胞苷(Ara-c)对HL-60白血病细胞增殖力的影响。
Objective : To study the effects of lentinan polysaccharide and Ara-c in the ability of proliferation on HL-60 cells .
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目的:建立测定阿糖胞苷(Ara-C)及其代谢产物阿糖尿苷(Ara-U)血药浓度的方法,并用于5例急性髓细胞白血病(AML)患者血药浓度监测。
OBJECTIVE : To develop a method for the determination of Cytarabine ( AraC ) and its metabolite ( uracil arabinoside , Ara-U ) in plasma of AML patients .