阿霉素

本文用琼脂糖电泳观察阿霉素和雷公藤内酯注射液对结肠癌细胞DNA的嵌合作用。

The intercalation of doxorubicin and triptolide injection with colon cancer cellular DNA was observed in this experiment .

HPLC荧光法检测转铁蛋白修饰的阿霉素脂质体在小鼠体内的含量

Determination of Doxorubicin Liposomes Modified with Transferrin in PCR Mice by HPLC With Fluorescence Detector

茶多酚联合维生素C对阿霉素肾毒性的保护作用

Protective Effect of Tea Polyphenol Combined with Vitamin C on Renal Damage Induced by Adriamycin

阿霉素铁（Ⅲ）配合物与DNA结合作用的研究

Studies on the interaction of adm · fe ( III ) with DNA

阿霉素肾病大鼠肾组织中核因子-κB活化与肾小管间质损害的关系

Correlation between Nuclear Factor - kappa B Activation and Renal Tubulointerstitial Injury in Adriamycin Nephrosis

阿霉素和安吖啶及其DNA复合物对小鼠的毒性和抗肿瘤作用

Study on the toxicity and antitumor activity of adriamycin-dna and amsacrine-dna complexes in mice

维生素B（12）对阿霉素解毒作用的实验研究

Studies on the Effect of Vitamin B_ ( 12 ) in Reducing the Toxicity of Adriamycin

这些结果为深入理解阿霉素与DNA的相互作用提供了帮助。

These results will be useful for further understanding the interaction of DNA with adriamycin .

阿霉素与X射线对体外培养乳鼠心肌细胞损伤的初步实验研究

Preliminary Empirical Study of Damage Induced by Adriamycin and X-ray in Cultured Rat Cardiac Myocytes

B组与C组一次性经尾静脉注射阿霉素7mg/kg。

Rats in groups B and C were injected with a single dose of 7mg / kg adriamycin via caudal vein .

方法回顾分析了130例肿瘤患者使用阿霉素前，同步12导联心电图的P波最大时间P波离散度。

Methods P-max time and P-wave dispersion in 12 conduct concurrent electrocardiographic were measured in 130 patients with tumors before ADM was administrated .

TRAIL联合阿霉素的体外抗肿瘤活性

Study on the antitumor activity in vitro of TRAIL combined with doxorubicin

本文采用HPLC柱切换技术建立了阿霉素（Adriamicin）血药浓度的测定方法。

A HPLC method for determination of adriamycin in plasma was established using column switching technique .

毫米波和阿霉素对K562细胞的影响

Millimeter wave and adriamycin for purging leukemic cells in vitro

结论阿霉素肾病大鼠肾皮质中NF-κB、AP-1DNA结合活性异常升高；

Conclusion The activities of NF - κ B and AP-1 blinding to their DNA sites in cortex of kidneys in rats with Adriamycin-induced nephrosis increase abnormally .

实验方法：K562/A02耐药性以MTT法检测阿霉素抑制细胞生长作用，计算耐药倍数。

The cell growth inhibition of K5662 / A02 cells was assayed using MTT method .

westernblot分析表明吗啡能够明显的抑制阿霉素介导的caspsae-3激活，Bax上调，Bcl-2下调以及线粒体中细胞色素c的释放。

Western blot analysis indicated that morphine dramatically inhibited doxorubicin-mediated caspase-3 , Bax and Bcl-2 activation and mitochondrial cytochrome c release .

在穿刺卵圆孔过程中CT引导穿刺的方向并确认针尖的位置，经造影确保穿刺针准确位于神经节内，然后向三叉神经半月节注射神经阻滞破坏药阿霉素。

Adriamycin was injected into trigeminal gasserian ganglion as a neurolytic agent after the identification when contrast medium spread properly inside the ganglion on CT monitor .

无PEG修饰的空白脂质体对阿霉素无吸附作用；PEG对阿霉素的吸附进程受PEG阿霉素配比、孵育时间的影响；

Both the PEG adriamycin ratio and incubation time affected the absorption of adriamycin to PEG ;

β-胡萝卜素对阿霉素致大鼠心肌组织的超氧化物歧化酶、谷胱甘肽过氧化物酶mRNA表达改变的影响

Effect of beta-carotene on adriamycin induced changes of expression of mRNA of superoxide dismutase and glutathione peroxidase in myocardial tissue of rats

阿霉素对人胚胸腺细胞IL-2产生及LAK活性的影响

Effects of doxorubicin on IL-2 release and LAK activity of human fetal thymocytes

以RT－PCR分析经联合应用阿霉素后，TRAIL基因的表达是否有所增加。

RT-PCR exams whether there was any change of the TRAIL gene expression after combination with DOX .

阿霉素控释剂对大鼠C6脑胶质瘤治疗的研究

Study of chemotherapy for rat C6 glioma using control released adriamycin

HPLC法测定阿霉素及其代谢物阿霉素醇、阿霉素酮在肿瘤病人中的血浆、细胞内的药代动力学

Study on the plasma and cellular pharmacokinetics of adriamycin and its main metabolites adriamycinol , adriamycinone in cancer patients by HPLC method

方法：采用RP-HPLC法测定阿霉素浓度。

METHODS Reversed phase HPLC was used .

阿霉素可以以剂量依赖性的方式降低肿瘤细胞中EGF的表达。

Doxorubicin could reduce the expression of EGF and EGFR in a dose dependent manner .

乳腺癌耐药细胞ER表达状态影响细胞对屈洛昔芬和阿霉素的敏感性

Status of Estrogen Receptor Affects the Drug Sensitivity of Drug Resistant MCF-7 / Adr Human Breast Cancer Cells to Droloxifene and Adriamycin

结果EGCG和阿霉素均表现为剂量和时间依赖的细胞抑制作用。

Results Either EGCG or adriamycin showed time-dependent an d dose-dependent cytotoxicity .

结果阿霉素肾病大鼠血浆IL-8浓度有所增高，苯那普利对肾病综合征大鼠IL-8浓度无明显影响。

Results The concentration of IL-8 was higher in the rats with adriamycin nephrosis than in the controls .

粉防己碱逆转耐阿霉素的人乳腺癌MCF-7细胞的抗凋亡作用

Reversal of Anti-Apoptotic Action by Tetrandrine in The Human Breast Carcinoma Doxorubicin Resistant MCF-7 Cells