非编码序列
- non-coding sequence
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目的:在人类基因组中,有98%的DNA序列属于非编码序列。
Objectives : 98 % of DNA sequence in human genome belongs to non-coding sequence .
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人αD型干扰素cDNA3′端非编码序列对该基因在大肠杆菌中表达的影响
Influence of human ifn - α d cDNA 3 ' non-coding sequence upon gene expression in E.coli
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合理建模非编码序列对正确识别DNA序列中的调控元件非常重要。
Modeling non coding background sequences appropriately is important for the detection of regulatory elements from DNA sequences .
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核基质附着区(matrixattachmentregions,MARs)是与核基质(或核骨架)特异结合的DNA序列,属于非编码序列,富含AT。
Matrix attachment regions ( MARs ) are DNA sequences that bind to the nuclear matrix , which tend to be noncoding sequences and AT rich .
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非编码序列的DNA结构在基因表达调节中起重要作用,B淋巴细胞的VDJ重组需要回文序列,回文序列涉及病毒转录、复制等多种生物学过程。
VDJ recombination of B lymphocytes needs palindromic sequences . In addition stem-loop structure is involved in viral transcription , replication and other biological processes .
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已有的研究表明,非编码序列的长度与基因表达水平有较强的负相关性。
Lengths of non-coding sequences correlate with gene expression levels significantly .
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核酸非编码序列信息指标的进一步分析
A Further Analysis of Informational Indices of Encoding Nucleic Acid Sequences
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真核生物基因组中的非编码序列
The non - coding sequences of eukaryotic genome
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构建三维参数空间区分完全基因组中的编码和非编码序列
Identification of Coding and Non-coding Sequences in a Complete Genome Forming Three-dimensional Parameter Space
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顺式作用元件是目前已知的具有重要调控功能的非编码序列;非编码序列的存在与真核生物基因表达调控密切相关;
The non-coding sequences have a close relation with the temperal and spatial expression of Eukaryotic genes .
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顺式作用元件通常为非编码序列,可影响自身基因的表达活性。
Cis-acting elements are usually non-coding sequences , and can affect the activity of its own gene expression .
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真核生物基因组中含有大量的非编码序列,其中主要是内含子和基因间隔序列。
Unlike in prokaryotes , there are many non-coding sequences in eukaryotes , including intron and intergenic sequence .
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在这些非编码序列中,重复序列占很大的比重,这些重复序列大部分是移动元件,包括转座子和逆转座子。
Most of non-coding sequences are repeat sequences , which most of them are mobile elements , including transposon and retrotransposon .
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其中很大一部分是非编码序列,其对编码基因的转录、翻译和表达等过程中有着重要的调控作用。
Some of them are non-coding sequences , these sequences were characterized to participate in regulation of gene transcription and translation .
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非编码序列,特别是内含子的起源,是一个重要的悬而未决的问题。
The origin of non-coding sequences , especially introns , is an outstanding issue that has been receiving continuous debate for the last two decades .
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结果表明,用d作编码区的特征参数是可行的,它可以很好地区分编码序列和非编码序列。
It is found d can be regarding as characteristic parameter of gene coding region , and d can clearly specify the coding region and non-coding region .
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非编码序列在人类基因组中占绝大的比例,所以研究它们的特征和偏好模体对理解非编码序列的功能和核小体定位是非常重要的。
Noncoding sequences occupy most of the human genome , thus studying their characters and preferential elements are important to our understanding of the noncoding sequence functions and nucleosome positioning .
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结果发现在整个基因组范围内编码序列的总体二核苷偏好性与重组率显著负相关,而对非编码序列来说却显著正相关。
Our results show that the overall dinucleotide bias is positively correlated with recombination rate for coding sequences while negatively correlated for introns and intergenic sequences that both are non-coding sequences .
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至目前,对肿瘤基因组的研究主要关注的是蛋白编码基因,而对有功能的非编码序列之改变的认识很缺乏。
However , studies on cancer genome so far have focused most heavily on protein-coding genes , and our knowledge on alterations of the functional noncoding sequences in cancer is largely absent .
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最近,人们对挖掘非编码序列中可能存在的功能片段以及非编码序列的演化和进化方面做了大量的工作。75-90%的真核生物基因组都被组装成作为染色质基本重复单元的核小体。
Recently , lots of work has been done to explore the putative functional elements in noncoding sequences and their evolution . 75-90 % of eukaryotic genomic DNA is wrapped in nucleosomes , the basic repeating unit of eukaryotic chromatin .
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以酵母全基因组中第一类的2505个编码序列和相对应的非编码序列为统计样本,给出了酵母编码起始区和编码终止区以及非编码区碱基的分布特征。
Based on the 2505 coding sequence and relative non coding sequence of the first category of yeast genes as statistical sample , the distribution of bases in the coding starting region , coding terminal region and non coding region of Yeast is given .
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肺癌细胞系线粒体DNA非编码区序列变异研究3个鼠源性肿瘤线粒体DNA编码区基因RFLP分析
Variation of mitochondrial DNA noncoding region in lung cancer cell lines The RFLP analysis on mutation of mtDNA from mouse tumors
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紫菜种内rDNA非编码区序列及系统发育分析
Sequences and Phylogeny Analysis of rDNA Noncoding Region in Intraspecies of Porphyra
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这一细节让他们作出结论:可能是遗传获得的非编码DNA序列、而不是基因变异才使得最大部分的转录因子结合位置发生变化。
This detail led them to conclude that inherited non-coding DNA sequences – not mutations in genes – may drive the lion 's share of differences in where transcription factors attach .
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小分子RNA家族中的一员µRNA,是一段非常短的非编码RNA序列,对多种生物学过程起调控作用。
MicroRNA , one of the small molecular RNA family , is a very small section of non-coding RNA sequence , which can regulate several biological processes .
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TMV蚕豆株系CP基因及3′端非编码区序列分析与表达
The analysis and expression of the 3 ′ unencoded end and CP gene of broad bean strain of TMV
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蓝舌病毒HbC3株S7基因5′非编码区序列分析
Sequence Analysis of S7 5 ′ - NCR Gene of Bluetongue Virus-HbC_3 Strain
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对SVM采用了拟南芥全序列数据,对序列中的编码区序列和非编码区序列进行了研究。
For the SVM classifier , we use the complete sequence of arabidopsis thaliana to research the coding region and the non coding region in DNA sequences .
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基于DC3算法的非编码区序列最大串联重复识别
Recognition of Maximal Tandem Repeats in Non-Coding Region Based on DC3 Algorithm
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本研究目的旨在测定3'非编码区序列。
This study was intended to determine the sequence of 3'non-coding region .