药物作用机制

这些结果对于了解HT的药物作用机制和提高临床化疗疗效具有重要意义。

These results are important to understand the mechanism of action of HT and to improve the effect of HT in cancer chemotherapy .

结合纳洛酮的药物作用机制谈临床应用新进展

Talk over the new progress of clinical application of naloxone with its mechanism of action

观察血小板内钙离子浓度的变化及细胞外钙离子对其影响，为探讨血小板内Ca＋＋与疾病的关系及阐明药物作用机制提供理论依据。

Objective To observe platelet calcium oscillation and the influence of extracellular Ca 2 + on it .

肾癌Fas表达异常与临床化疗药物作用机制的研究

Study on Fas expression and the action of chemotherapeutic drugs in renal cell carcinoma

背景与目的：近年来兴起的DNA芯片技术能在一次杂交中同时监测数以千计的基因表达，能大大加速肿瘤药物作用机制的研究和药物治疗靶点的发现。

BACKGROUND & OBJECTIVE : The advanced technique of DNA microarray makes it possible to monitor the expression of thousands of genes simultaneously in one hybridization experiment .

单克隆抗体（MoAb）与细胞毒类药物作用机制不同，不良反应无重叠，与化疗有协同作用。结论不同剂量GT对神经细胞的损害机制不同。

Monoclonal antibodies ( MoAbs ) have different mechanism and adverse effects compared with cytotoxic agents . Conclusion This indicated that different mechanism existed between in the high and low GT concentration .

喜树碱类药物作用机制及其耐药现状的研究进展

Research development on the mechanism of camptothecins and its resistance

抗结核药物作用机制及构效关系的研究进展

Research advances on the activity mechanism and structure-activity relationships of anti-tuberculosis agents

表达谱芯片技术在药物作用机制研究中的应用

The application of cDNA microarrays technology in mechanism of drug

新的研究发现能阐明这些药物作用机制的附加途径。

The new discovery could demonstrate an additional way in which these drugs work .

沙利度胺等非经典抗炎药物作用机制研究

Studies on Molecular Targets of Non-classical Anti-Inflammatory Drugs

有待加强对药物作用机制、肿瘤复发机制方面的研究。

Mechanisms of drug effect and recurrence of glioblastoma should be put in more emphasis for research work .

结论应根据患病原因及类别、药物作用机制及毒理作用等情况选择合适的药物。

Conclusions : Suitable drug should be selected according to the class and reason of disease , effective mechanism and toxicity of drug , etc.

现概述代谢物组学在新药筛选、药物作用机制研究、个体化用药研究方面的应用。

In this paper , its application in screening of new drug , in drug mechanism research and in study of individualized drug use are reviewed .

对本研究中发现的其它中药阳性组分中单体化合物的分离和功能鉴定，也许能有助于发现新的药物作用机制以及高活性的抗黑色素瘤新药。

Isolation and functional characterization of single compounds from other positive fraction of different herbs may identify new natural compounds with new mechanisms and ideal therapeutic properties against human melanoma .

本文就醋酸烯诺孕酮的化学结构、激素活性、药代动力学特性、临床有效率、副作用、药物作用机制以及阴道环剂型等方面作一综述。

Structure , hormonal activities , pharmacokinetics , contraception efficacy in clinical trials , side effects , mechanism of effects and vaginal ring of ST 1435 were reviewed in this paper .

应用膜片钳技术可以证实细胞膜上离子通道的存在并能对其电生理特性、分子结构、药物作用机制等进行深入的研究。

Application of the patch-clamp technique can demonstrate the existences of ion channels and provide valuable information for ion channels , including their electrophysiological properties , molecular structures and the mechanism of drug action .

本文着重从重大疾病防治药物作用机制与新靶点研究，药物研究的新理论、新方法和新技术两个方面概要地介绍了药学科学基础研究中的一些重要前沿领域。

Some important frontier areas in fundamental research of pharmaceutical sciences are discussed in this paper , especially the studying of new mechanisms and targets of drug and the new theories , methods and techniques for discovering new drug .

今后，应加强证候类型标准化、有效方药筛选、药物作用机制、剂型改革等方面的基础与临床研究，进一步提高中医药治疗心脏传导阻滞的水平。

From now on , we should strengthen the basic and clinical research on the standardizing types of syndrome 、 screening effective prescriptions 、 pharmacologic mechanism of drugs and reformation of pharmacol preparaton , further promote the levels of TCM in treating heart block .

背景健脾补肾中药对实验性脾虚证有较好的防治作用，细胞因子水平的变化是否与药物作用机制有关。

BACKGROUND : The spleen invigorating and kidney nourishing ( SIKN ) Chinese herb has preferable preventive and therapeutic effect in the experimental spleen deficiency syndrome ( SDS ) . Whether the alteration of the levels of cytokines relates with the mechanism of medicine ?

在企图了解抗心律失常药物作用的机制中产生某些困难是有一些原因的。

Difficulties arise in attempting to understand the mechanisms of antiarrhythmic drug action for several reasons .

目的：评价强化降脂治疗对老年不稳定性心绞痛（UAP）病人预后的影响，探讨降脂药物的作用机制。

Objective : To evaluate the prognostic value of intensive lipid lowering treatment in old patients with unstable angina pectoris ( UAP ) and study the mechanism of lipid lowering drugs .

药物的作用机制是阿托伐他汀钙导致细胞凋亡相关的蛋白表达量发生改变，使促使细胞增生的Bcl-2、MMP-2蛋白表达降低，同时调节Bax蛋白高表达，bax/bcl-2增大，这可能是其作用机制之一。

The role of mechanism of drug atorvastatin calcium leads to apoptosis-related protein expression changes that promote cell proliferation of Bcl-2 , MMP-2 protein expression decreased , while Bax protein in regulating expression , bax / bcl-2 increases , which may be one of the mechanisms .

本文简述了高血压病的现状与致病机理以及各种抗高血压药物的作用机制和研究进展，重点介绍了血管紧张素转化酶抑制剂（ACEI）的构效关系、药代动力学性质以及主要副作用。

The situation and nosogenesis of hypertension were described briefly in this paper . The action mechanism and development of antihypertensive drugs were also introduced , especially of the structure-activity relationships , pharmacokinetic properties and main side-effects of angiotensin converting enzyme inhibitors ( ACEI ) .

且对药物的作用机制及疗效标准的判断作了探讨。

The pharmacological mechanism of insulin and the standard of curative effect were discussed .

现有多药耐药性逆转药物由于作用机制单一、选择性差、副作用大等缺点，临床治疗效果不佳。

The single mechanism , poor selectivity and serious side-effects of current MDR-reversing agents limit their clinical application .

结合临床药物的作用机制，内质网应激可能成为治疗肝脏损伤相关疾病的新靶点。

Combining with the clinical studies , ERS might be a novel therapeutic target in liver injury-related disease .

这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应，后者可以促进肿瘤细胞生长。

The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth .

本文介绍了常用抗血小板药物的作用机制以及指南性建议和临床试验证据。

This article introduces the mechanism of currently available antiplatelet drugs as well as their practice guidelines and evidence from clinical trials .

一般认为，青蒿素类药物的作用机制与其结构中的内过氧桥有关，最近又提出一些与以往不同的观点。

It is generally agreed that artemisinins action mechanism is associated with the endoperoxide function , but some researchers have some other ideas .