半数致死量

试验旨在确定肉鸭亚硝酸盐的半数致死量（LD（50）），探讨鸭饲料中亚硝酸盐的无明显作用水平（NOEL），为国家饲料中亚硝酸盐允许量标准的制修订提供科学依据。

The experiments were conducted to determine the median lethal dose ( LD50 ) of nitrites to ducks , and seek the no-observed effect level ( NOEL ) in duck feeds .

方法：通过急性毒性实验半数致死量（LD50）的检测，验证人参多糖是否降低氟脲嘧啶多相脂质体的毒性。

Methods : Acute toxicity tests of median lethal dose ( LD_ ( 50 )) were performed to test whether panax polysaccharide could reduce the toxicity and adverse effect of compound fluorouracil lipid .

以序贯法研究不同剂量的P对小鼠静脉注射K的半数致死量（LD50）的影响，并探讨P对清醒家兔静注K的呼吸循环效应的影响。

The influence of P on the circulatory and respiratory effects of K was studied in rabbits .

目的测定百草枯对小鼠的半数致死量（halflethaldose，LD50）。

Objective To measure the half lethal dose ( LD_ ( 50 )) of paraquat in mice .

半数致死量LD（50）的百分偏差和渐近方差

Percentage Bias and Variance of LD_50

方法以Bliss法计算半数致死量（LD50）；

Methods LD_ ( 50 ) was measured by Bliss ;

方法：喘安小鼠灌胃测定半数致死量（LD50）。

Methods : To measure 50 % lethal dose by lavage .

用改良寇氏法计算半数致死量（LD50）及95%可信限。

The LD50 and 95 % creditability were calculated with developed Karber Method .

龙葵素对KM小鼠的半数致死量（L氏，）为434mg/kg体重。

The LD50 of solanine was estimated to be 434 mg / kg BW in mice .

方法：采用溶血试验测定红细胞半数致死量（LD50）。

Method : The red cell LD_ 50 was determined by the hemolytic experiment .

方法：经典的半数致死量LD50测定法。

Method : Classical LD50 test .

其半数致死量（LD50）为4.1×104个细菌。

The 50 % lethal dose of the bacterium was 4 1 × 10 4 cpf / mL.

结果破壁灵芝孢子油对雌雄小鼠经口半数致死量（LD50）均大于10g/kg体重，为实际无毒级物质；

Results The orally LD50 of broken cellwall lucid ganoderma spore is more than 10 g / kg ;

结果急性毒性实验中，核桃提取物经口半数致死量（LD50）10g/kg体重；

Results The oral LD 50 of walnut extract was more than 10 g / kg body weight ;

观察10d动物的存活情况，计算昆明小鼠单宁经口半数致死量（LD50）。

The death ratios were observed and the median lethal dose ( LD 50 ) was calculated .

邻甲苯胺经口半数致死量为755mg／kg，属低毒类。

The LD50 of o-toluidine in mice by mouth is 755mg / kg . o-toluidine has lower toxicity .

采用体外微量细胞病变抑制实验及体内半数致死量LD（50）测定法，分别观察海藻硫酸多糖911对乙型脑炎病毒的作用。

The effects of marine polysaccharide sulfate-911 on encephalitis B virus was investigated through in vitro study of the inhibition on trace cellular damage and the determination of LD50 .

致病力明显降低，对小白鼠的半数致死量大于1.0×108CFU（ColonyFormingUnits）。

In addition , the pathogenicity capability was greatly decreased and the 50 % lethal dose for mice was more than 1.0 × 108 CFU ( colony forming units ) .

病毒抗原激活C3的活性，与病毒核衣壳蛋白（nucleocapsidprotein）的含量及毒株对乳鼠的半数致死量有关，并可被特异性抗体（IgG）所中和。

Ability of activating C_3 of EHFV antigens was related to the content of EHFV nucleocapsid protein and LD50 of virus strain to suckling mice , which was neutralized by specific antibody ( IgG ) .

目的观察百草枯（Paraquat，PQ）对小鼠的急性毒性，计算其半数致死量（LD50）。

OBJECTIVE To explore the acute toxicity of Paraquat ( PQ ) in mice and calculate its 50 % lethal dose ( LD50 ) .

通过对合成的产物进行急性经口毒性试验，发现其经口半数致死量（LD50，mediumlethaldose）大于5.5g/Kg，按照急性毒性分级标准确定该依布硒林衍生物属实际无毒级。

The oral acute toxicity test showed LD50 ( medium lethal dose ) > 5.5 g / Kg . Such result demonstrates that the synthesized product is nontoxic according to the classification of acute toxicity standard .

【方法】用简化机率法，计算小鼠给药的半数致死量（LD50）。

【 Methods 】 Count the value of the LD_ ( 50 ) of prostate suppository offering to mouse by the way of simplified rate .

小鼠口服及腹腔注射给药不同剂量的P2，计算其最大耐受量（MTD）和半数致死量（LD50）。

The maximum tolerable dose ( MTD ) and LD50 of mice were determined after different doses of P2 were given with oral administration and intraperitoneal injection .

通过灌胃口服方式，研究了硝酸钐对雄性小鼠的半数致死量（LD50），并探讨了不同染毒剂量下存活小鼠的脏器系数、精子质量的变化。

Effects of samarium nitrate on acute toxicity in male mice and organ coefficients and sperm quality of the survived mice were studied by oral infection .

方法将KM小鼠随机分为雌、雄2组，进行急性经口半数致死量（LD50）试验和蓄积毒性试验。

Methods The KM mice were randomly divided into female and male groups , the experiment of the LD50 of p-dichlorobenzene by acute oral intake and the cumulative toxicity test had been conducted .

方法用小鼠半数致死量（LD50）及生化指标的变化来表征斑蝥素的毒性，用小鼠急性死亡率法测定斑螫素药物动力学参数。

METHODS The toxicity of cantharidin was expressed at lethal dose 50 and biochemical indexes , apparent pharmacokinetic parameters of cantharidin were determined by using acute mortality of mice .

根据改良寇氏法进行毒理学实验，用昆明小白鼠腹腔注射急性毒性实验，测得30%硼葡萄糖酸钙注射液的半数致死量（LD（50））为了.77g/kg体重。

Doing the acute toxicological experiment with KunMing mice according to the improving Kou 's methods by injecting 30 % Boric acid glucal into abdominal cavity of mice , We gained LD50 of the injection is 7.77g/kg body weight ;

方法：不同浓度硝普钠诱导软骨细胞凋亡，检测不同时间软骨细胞半数致死量（LD50）的硝普钠浓度；

Methods : The chondrocytes were treated with different concentrations of SNP and the cartilage cells were sacrificed at different time points to measure their LD50 concentration of SNP respectively .

基于Bliss概率单位法，编写了用于计算半数致死量（LD50）的SAS程序（LD50-SAS）。

A SAS program to calculate median lethal dosage ( LD_ ( 50 )) of pesticides , named LD50-SAS , was developed based on the algorithms established by Bliss .

经对鸡胚平均致死时间、鸡胚半数致死量、对鸭胚和鸡、鸭的致死性测定及荧光PCR检测，证明分离毒为温和型毒株。

The isolated virus was proved to be a strain of moderate virus by ( detecting ) its mean death time to chicken embryo , LD_ ( 50 ) to SPF chicken embryo , lethality to duck embryos , chickens and ducks , and by fluorescent PCR detection .