调节蛋白质

一个特定的基因变化发生在一段名为EPAS1的DNA上，其编码调节蛋白质。

One particular genetic change occurred in a stretch of DNA known as EPAS1 , which codes for a regulatory protein .

为进一步确定哺乳动物蛋白酶体的组份和相关调节蛋白质，邱小波教授等人改良了基于亲和纯化的方法来快速从哺乳动物细胞中纯化26S蛋白酶体。

To better define its composition and associated regulatory proteins , Qiu et al developed affinity methods to rapidly purify 26S proteasomes from mammalian cells .

现就最新资料，对IGFⅠ调节蛋白质代谢方面作用作一综述。

In this article , the recent data on protein metabolism of IGF - ⅰ are reviewed .

细胞蛋白质活动场所的变更是调节蛋白质功能的另一重要方式，RR也不例外。

Like other proteins , one of the important ways to regulate RR function is to alter RR subunits ' localizations .

G1／S调控点调节蛋白质p16控制GaltmRNA转录、表面和总GalT活性。

Gl / S checkpoint regulation proteins such as p ! 6 control GalT mRNA transcription and GalT surface and total activity .

磷酸化作为翻译后的主要手段，参与调节蛋白质及细胞骨架的功能。

Phosphorylation is a major post-translational method for regulating protein function , including that of the cytoskeleton .

内涵体转运是真核调节蛋白质功能的一个重要手段。

In eukaryotic cells , endosome trafficking is an important method to regulate the function of proteins .

蛋白质的翻译后修饰是一种调节蛋白质定位、功能、翻转的正常生理机制。

The post-translational modifications ( PTMs ) of proteins is a common biological mechanism for regulating protein localization , function , and turnover .

结论灵芪蠲肝液能减少慢性肝损伤氧自由基和NO，调节蛋白质代谢。

ConclusionLQL can reduce production of oxygen free radicals and the NO levels and accommodate metabolism of albumen on CCl_4 induced chronic liver damage .

能影响几乎所有的组织和细胞，其主要作用是刺激骨、软骨细胞的生长和分化，调节蛋白质、糖及脂肪的代谢。

It promotes the growth and differentiation of bone and cartilage cell , adjusts the metabolism of protein , carbohydrate and fat in almost all tissue and cell .

研究发现在所有已知物种中均存在蛋白翻译后修饰，它是指对新合成的多肽链或蛋白质进行的化学修饰从而调节蛋白质的功能（如定位、稳定性和特异性等）以及寿命。

Many research detected that post-translational modification of proteins is observed in all known living organisms , and it is the chemistry modification to new synthetic polypeptide chains or proteins . Post-translational modification might regulate many functions of proteins ( such as location , stability and specificity ) and life .

新近研究提示，在基础和应激条件下，生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白（GHIGFIGFBP）轴对调节肌肉蛋白质代谢起着核心作用。

Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condition .

本文详细介绍了他们的发现，重点介绍了泛素调节下蛋白质降解所需要的各种物质及其机理。

The article introduce their discovery , especially the substances wanted in the course of the ubiquitin-mediated protein degradation and the mechanism .

在许多情况下，肽发挥着不可替代的作用，在酶的活性调节，蛋白质生物合成等重要生理过程中起着关键的作用。

Under many circumstances , the function of peptides is exclusive . They play a very important role in the process of activity control of enzymes and synthesis of protein .

这种相互作用涉及许多细胞内事件，如非受体信号传导、转录调节、蛋白质降解等等，并且这种相互作用的变化会直接或间接影响到人体的正常生理代谢功能而引起疾病。

The interactions are involved in many intracellular affairs , such as non receptor signaling , transcriptional regulation and protein degradation . Changes in these interactions will directly or indirectly interfere in normal metabolic processes and cause diseases .

异三聚体GTP结合蛋白（heterotrimericGTP-bindingprotein，G蛋白）是活细胞内一类具有重要生理调节功能的蛋白质。

Heterotrimeric GTP-binding protein is a kind of protein with important physiologically regulatory functions in living cells .

白细胞介素11（IL-11）是一种具有调节功能的蛋白质。

Interleukin-11 ( IL-11 ) is a kind of muti-function protein .

这两种新药分别是安进公司（Amgen）研发的evolocumab，以及赛诺菲和瑞泽恩（SanofiandRegeneron）制药公司的alirocumab，它们的作用机理都是抑制PCSK9——体内的一种协助调节胆固醇的蛋白质。

The drugs , evolocumab from Amgen and alirocumab from Sanofi and Regeneron , inhibit a protein in the body called PCSK9 that helps regulate cholesterol .

干扰素（Interferon，IFN）是动物机体感染病毒或接种疫苗后产生的一类具有抗病毒和免疫调节功能的蛋白质，是动物抵御病毒入侵的第一道防线。

Interferon are cytokines that function as antiviral factors and immune regulators , which are naturally produced by the immune system of mammal immediately following viral infection or viral vaccination . The interferon system is the first frontier of defense against viral infection in mammals .

结论：利用生物信息学方法可初步预测FAM92A1为一细胞核内具有调节作用的蛋白质，其在细胞增殖和分化的精确调控方面可能起着重要作用。

Conclusion According to the preliminary inference , FAM92A1 is a kind of regulatory protein in nucleus , which may play an important role in the proliferation and differentiation in development .

大部分的200家族蛋白成员还有一个与干扰素反应和细胞凋亡相关的结构域（DAPIN）/PYRIN，与细胞凋亡和免疫反应信号途径的调节过程中蛋白质之间相互作用密切相关。

The a and b domains . Most of the IFI-200 proteins also possess a domain in apoptosis and interferon response ( DAPIN ) / PYRIN domain , which is a conserved motif associated with protein-protein interactions in the regulation of apoptotic and inflammatory signaling pathways .

结论：复方红景天可调节运动后蛋白质代谢水平。

Conclusion : CRM can adjust the level of protein metabolism after exercises .

同时基因被转变的途径是被一个基因调节器的蛋白质叫FOXO

And the way that they 're switched on is by a gene regulator protein called FOXO .

说明选取特定品种种植在适宜的生态条件下对调节大麦籽粒蛋白质及其组分含量是可行的，尤其对大麦籽粒蛋白质含量的调控作用十分有效。

These results explain that the way to select specific cultivar and plant under suitable ecological condition is possible to control the contents of protein and its components in barley grain , especially the regulative function to the protein content of barley grain extremely effective .

一般可以通过调节pH，改变蛋白质和/或吸附剂的所带电荷，利用静电排斥作用协助洗脱。

The elution is induced with the electrostatic repulsion between the protein and adsorbents by adjusting the pH value .

大肠埃希氏菌K-12胞浆热调节蛋白及其相关蛋白质复合物的研究

Cytoplasmic Proteins and Protein Complexes Related with Heat-regulation in Escherichia Coli K-12

胰岛素可能通过促进细胞蛋白质生物合成相关的基因表达以及AST、ALT活性等和氨基酸代谢相关的酶调节，提高机体蛋白质含量；

Via promoting gene expression of cellular biosynthesis protein and activity regulation of amino acid metabolic enzymes such as ALT and AST , Insulin increases body protein content ;

microRNA（miRNA，即微小RNA）是一类长约21~25个核苷酸的小分子非编码RNA，它可以通过与特定mRNA结合或调节特定mRNA的蛋白质翻译过程来调控基因的表达。

Micro RNA ( miRNA ) is the fragment of non-coding small RNAs and consists of 21-25 ribonucleotide . It can regulated gene expression by either binding to or regulating the translation process of some specific mRNA .

目的：研究Ada蛋白质对alkA基因表达的调节，探讨Ada蛋白质与alkA基因有效转录的关系。

Objective : We investigated the relationship between Ada protein and the effective transcription of alkA gene in order to study the regulation of alkA gene expression by Ada protein .

通过核质转运调节细胞凋亡的蛋白质

Proteins Regulating Cell Apoptosis through Nucleocytoplasmic Transport