重组修复
- recombinational repair;recombination repair
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目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径,包括碱基切除修复、同源重组修复和非同源末端重接。
Most members of the XRCC genes family participated in several DNA repair pathways , including base excision repair , homologous recombination repair and non-homologous end joining .
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针对不同的DNA损伤。细胞内有许多不同的修复方式对其进行修复,包括碱基切除修复、核苷酸切除修复、错配修复、同源重组修复等。
There are many DNA repair pathways to different DNA lesions , including base excision repair , nucleotide excision repair , mismatch repair and homologous recombination repair .
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五氧化二钒、四氯化钛在枯草杆菌DNA重组修复试验中的联合致突变性研究
Research on the Combining Mutagenicity of V_2O_5 and Ticl_4 in the Recombination-repairing Assay of the DNA of B.Subtilis
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[目的]研究枯草杆菌芽孢重组修复试验中增加冷培养对金属化合物和间接致变物DNA损伤试验的影响。
To study the effect of spore rec assay with B.subtilis with an additional cold incubation to determine the DNA damage of metal and indirect mutagens .
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本文就枯草杆菌重组修复试验和Ames试验做了一些比较研究。
Comparative studies of Rec assay and Ames test were carried out .
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人类细胞内存在着完整的修复系统,其中包括碱基切除修复系统(baseexcisionrepair,BER)和同源重组修复系统(HomologousRecombination,HR)。
There are complete repair system in normal cells , including base excision repair system ( BER ) and homologous recombination repair system ( HR ) .
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结论:Ku蛋白在放射引起DNA双链断裂修复、再连接中具有重要作用,Ku80蛋白缺乏细胞的DNA双链断裂后的重组修复能力的缺陷是固有的,并不因放射剂量的改变而不同。
Conclusion : Ku protein plays an important role in rejoining of DNA double stand breaks ( DSBs ) induced by x-ray .
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本研究采用枯草杆菌DNA重组修复试验,检测了24种有机磷农药的诱变性,并分析了有机磷的化学结构与诱变性的关系及其可能的诱变机理。
A total of 24 organophosphorus pesticides ( OPPs ) were tested for mutagenicity in B. subtilis DNA repair test , and the chemical structure and mutagenicity relationship were analyzed and the mechanism of mutagenicity was discussed .
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推测阳性有机磷农药作为烷化剂,主要是使鸟嘌呤的N-7位甲基化,引起碱基置换;或形成加合物,造成交联,从而引发DNA重组修复而致突变。
The results suggest that positive OPPs may be a kind of alkylating agent , mainly methylated the N-7 position of guanine and induced base pair substitution of formed adduct , and cross linkage to induce DNA recombination and mutation .
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目的探讨辐射损伤后HR24L修复蛋白复合物的形成,为HR24L参与切除修复和重组修复提供生化证据。
Objective To investigate HR24L repair complex after DNA damage induced by radiation and provide biochemical evidence of the participation of HR24L in DNA excision repair and recombination repair .
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DNA合成、重组及修复基因如POLK;
DNA synthesis , recombination and repair genes such as POLK etc ;
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研究大肠杆菌单链结合蛋白(single-strandedDNA-bindingprotein,SSB)与单链DNA(single-strandedDNA,ssDNA)的相互作用对于了解其在DNA复制、重组和修复中的作用是非常重要的。
Study of interaction of E. coli single-stranded DNA - binding protein ( SSB ) with its substrate , single-stranded DNA ( ssDNA ), is very important for understanding its essential roles in replication , recombination and repair of DNA .
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这些结果表明大脑中枢代表区发生改变,运动皮层有效连接网络发生重构,实现了大脑功能重组和自修复,这就是大脑神经可塑性的充分体现。
The results indicated that the district on behalf of the brain function has changed , the motor cortex effective network is reconstructed to realize functional reorganization and self-repair , which is a full expression of brain plasticity .
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在大肠杆菌中,RadA蛋白也参与了重组和DNA损伤修复过程,但远没有在古细菌中的功能那么重要。
In Escherichia coli , it takes part in conjugational recombination and DNA repair but is not as important as that in archaea .
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重组人工骨移植修复节段性骨缺损的实验研究
An experimental study on recombinant artificial bone substitute for repairing segmental bone defect in rabbits