骨质硬化

在本研究中，我们基于Cre-LoxP系统获得了成骨细胞特异性Pten基因敲除小鼠，发现Pten基因敲除小鼠发生骨质硬化症。

In this study , we created osteoblast-specific Pten knockout mice ( Ptenflox / flox ; OC-Cre ) using the Cre – LoxP system . We found that Pten mutant mice exhibited osteopetrosis phynotype .

期20个，CT表现为骨质硬化、囊变，新月征阳性，骨质轻度碎裂，关节面轻度塌陷；

Stage ⅲ was 20 places , CT showed osteosclerosis , cystic hyalomere , meniscus sign , slight fraction of bone , slight joint surface depressed ;

晚期X线及CT呈不规则、迂曲状骨质硬化，MRT1WI及T2WI均呈低信号。

In the later stages , the bone infarct was characterize by irregular sclerosis and tortuous calcification on X-ray and CT , and by low-signal on both T_1WI and T_2WI .

结果：LPMN的CT表现为：（1）椎体后上缘或下缘局限性骨缺损，缺损区周围骨质硬化；

Results : The CT features included : ( 1 ) focal bony defect in the posterior superior or posterior inferior edge of the affected vertebral body with sclerotic edge ;

平片改变主要呈云雾状骨质硬化，边界不清；

The main X-ray change was bone sclerosis with unclear boundary .

影像学征象包括密度不均的班片状影和骨质硬化以及关节面的骨质塌陷。

Radiographic findings include patchy areas of lucency and sclerosis as well as bony collapse at articular surfaces .

局限性骨质硬化：X线10例，MR4例；

Local sclerosis of the bony structure adjacent to the lesion was discovered by X-ray in 10 cases , by MRI in 4 cases ;

X线表现以骨质硬化，髓腔闭塞为基本特征，椎体夹心征及髂骨同心圆征为其特征性表现。

The basic X ray manifestations were bone sclerosis and bone cavity occlusion , the characteristics were " filling with filling " in centrum and " homocentric circle " in ilium .

邻近病灶端骨质轻度硬化：X线16例，CT14例，MR8例；

Mild sclerosis of the bony structure adjacent to the lesion were discovered by X-ray in 16 cases , by CT in 14 cases and by MR in 8 cases .

鼻窦窦壁骨质增生硬化.其中6例上颌窦壁骨质明显增厚。

( 3 ) hyperostosis of sinus paranasal walls , six of them obviously .

岩尖部骨质以硬化型居多，占42%。岩骨后脑膜瘤（附82例报告）

About 42 % of the petrosal apex of temporal bones are constructive type .

结果：大多数病例表现为窦腔软组织内散在不规则钙化密度影、单独存在的骨质增生硬化。

Results The representing anomaly calcified shade among the parenchyma in the sinus is the characteristic representation of mycosis of sinus .

所有受犯鼻窦均伴有窦壁骨质增厚和硬化。91.3%的病例在高密度软组织病变内还可见钙化。

All cases had bone thickening and sclerosis of the wall of sinus , and 91.3 % cases had calcification in the high density soft tissue lesion .

早期上颌窦内壁破坏，晚期鼻窦骨质增生、硬化，窦壁增厚，出现双线征。

Erosion of the medial wall of maxillary sinus in early stage , followed by hyperostosis , osteosclerosis and double line sign of new bone formation in the thickened sinus wall .

CT表现为骨质破坏伴骨硬化缘环绕、死骨，冷脓肿形成及脓肿壁钙化。

CT findings were as follows : destruction of bone and surrounding osteosclerosis , sequestrum , formation of cold abscess and calcification of the wall ;

对此68例临床症状不典型的患者，用对比分析平片、多层CT二种检查方法对骨质破坏、骨质硬化、骨膜反应、骨髓腔受累、死骨等征象的显示进行比较。

The demonstrating extent of bone destruction , osteosclerosis , periosteal reaction , involving of marrow lumen and sequestrum were compared among plain film and multi-slice CT .

老年人骨质疏松与动脉硬化关系的初步探讨

Relationship between osteoporosis and arteriosclerosis in elder

目的通过对骨密度与冠状动脉钙化积分、颈动脉内中膜厚度及斑块关系的分析，探讨骨质疏松与动脉硬化的关系。

Objective To analyse the corelation of bone mineral density and coronary artery calcification score , carotid arterial intima-media thickness , plaque , and to explore the relationship between osteoporosis and arteriosclerosis in elderly patients .

结果鼻腔鼻窦内翻乳头状瘤主要表现为单侧鼻腔鼻窦呈匍匐生长的软组织团块，轻到中度增强，可伴有骨质破坏和骨质硬化。

Results The CT findings of inverted papilloma of the nose and paranasal sinuses were the crawling growths of soft-tissue mass in the one side of the nose and paranasal , there were slight to moderate enhancement and probably with destruction of bone and osteosclerosis .

上颌骨病变累及齿槽骨，形成不规则的骨质缺损，部分骨质边缘硬化；

Lesions situated in superior maxillary bone involved alveolar bone forming rugged bone defect and in part hardened edge .

结果恶性纤维组织细胞瘤X线平片主要表现为大块状骨质破坏，界限不清，无骨质硬化、肿瘤骨和骨膜增生，多发生于管状骨，早期软组织肿块不明显等。

Results The mostly X-ray plain film of malignant fibrous histiocytoma presented massive destruction of bone , no clear limit , no osteosclerosis , tumor bone and periosteal proliferation .