组学

pathway预测是后基因组时代各类组学研究的基础，已成为近年来生物信息学的研究热点之一。

Pathway prediction is the basis of various types of omics in post-genomic era . With the extreme importance , it has become one of the focuses of bioinformatics in recent years .

我们通常采用基于典型相关分析或偏最小二乘回归（PLS）的方法融合组学数据，因为它们的计算性能比较好。

We usually adopt methods based on canonical correlation analysis or partial least-squares regression ( PLS ) to integrate omics data sets due to their acceptable computational performance .

低叶绿素b水稻突变体类囊体膜的比较蛋白质组学

Comparative Proteomics of Thylakoid Membrane From a Low Chlorophyll b Rice and Its Wild Type

首先，我们将该策略应用于大肠杆菌N末端肽组学研究中。

Firstly , the whole strategy was applied on the research of proteins N-terminal peptides .

目前应用蛋白质组学技术的重要研究工具之一质谱（massSpectrometry，MS）技术研究UPS系统还处于起步阶段。

The mass spectrometry-based proteomics techniques are powerful tools in the research of UPS .

细胞核PMLbody动力学及PRC1中体微管构架的分子与蛋白质组学解析

Molecular and Proteomics Dissection of Nuclear PML Body and PRC 1 Central Spindle Organization

本文从病理机制（特别是蛋白质翻译后修饰）、发现临床生物标签及治疗药物三个方面，对蛋白质组学在AD中的研究进展进行了综述。

The three aspects about the progresses in proteomics researches of AD were reviewed in this article .

结直肠癌DukesB、C、D期患者血清比较蛋白质组学研究

Comparative proteomics analysis in serum of colorectal carcinomas in Dukes B , C , D stages

高原鼠兔和Wistar大鼠骨骼肌线粒体的比较蛋白质组学初步研究

Comparative proteomic analysis of plateau Pika and Wistar rat gastrocnemius mitochondria

HBV转基因小鼠的肝脏蛋白质组学研究

Proteomic Analyses of HBV Transgenic Mice

血清蛋白质组学研究中白蛋白和IgG去除方法的建立与评价

Establishment and evaluation of the method for removing albumin and IgG in serum proteomics

本综述主要介绍了应用蛋白质组学技术研究UPS系统的研究现状以及存在的问题。

The recent advance in the study of UPS by proteomics techniques is briefly reviewed .

选取蛋白进行westernblot和免疫组织化学实验验证蛋白质组学的研究结果。

The results from simultaneous proteomic profiling were further validated by Western Blot of selected proteins and immunohistochemistry . RESULTS : 1 .

乳腺癌蛋白质组学研究中样品制备及SDS-PAGE的技术探讨

Exploring Technique of Sample Making and SDS-PAGE in Proteomics of Breast Cancer Research

目的以蛋白质组学研究为基础，分析2003～2005年间我国流脑暴发流行期间C群脑膜炎奈瑟菌菌株分布特征。

Objective This study was conducted to analyze the distribution characteristics of the serogroup C Neisseria meningitidis strains isolated during the epidemic outbreaks between 2003 and 2005 in China .

Sprague-Dawley大鼠肾脏急性缺血再灌注损伤的代谢组学研究

Metabolomics analysis of renal acute ischemia / reperfusion injury in Sprague-Dawley rats

目的从粪便上清液代谢组学及基因组学探讨类风湿关节炎（Rheumatoidarthritis，简称RA）脾虚证的中医证候实质。

Objective : To study the spleen deficiency syndrome of rheumatoid arthritis from fecal supernatant metabonomics and Genomics of traditional Chinese medicine .

感染布氏杆菌后的THP-1细胞的蛋白质组学研究

Comparative proteomics research on THP-1 cells infected with Brucella

幽门螺杆菌CagA蛋白与微囊藻毒素对胃肠道上皮细胞作用的蛋白质组学研究

Proteomic Analysis of the Effect of H.Pylori CagA and Microcystin on Gastrointestinal Tract Epithelial Cells

利用代谢组学技术对功能性消化不良（FD）女性患者血浆中代谢产物的变化进行研究。

Metabonomics was applied to study the changes in plasma metabolites of female patients with functional dyspepsia ( FD ) .

鼻息肉的2-DE图谱建立和蛋白质组学分析

Establishment of 2 - dimensional gel electrophoresis map and analysis of proteomics from human nasal polyps

受病变累及的运动中枢fMR表现功能蛋白质组学

The functional MR study of motor cortex involved by intracranial lesions

ACC细胞肿瘤肺转移及P19细胞神经元分化有关的差异蛋白质组学

Comparative Proteomic Analysis of ACC Cell Tumor Metastasis Associated and P19 Cell Neuronal Differentiation - associated Proteins

目的：建立测定K562及K562/A细胞内核苷类代谢物含量的高效液相色谱法，用于两者代谢组学研究。

Objective : To establish a reversed-phase ion-pair high-performance liquid chromatographic method for simultaneous determination of nucleotides and nucleosides in K562 and K562 / A cell lines .

植物功能基因组学的研究方法主要包括：表达序列标签（EST）、基因表达序列分析（SAGE）c、DNA微阵列和DNA芯片、反求遗传学、蛋白质组学和生物信息学；

The research metheds of functional genomics , mainly include Expressed Sequence Tag ( EST ), Serial Analysis of Gene Expression ( SAGE ), cDNA microarrays and DNA chips , Reverse genetics , Proteomics and Bioinformatics .

目的：建立白血病细胞HL60蛋白质组学研究的技术体系。

Objective : To establish the techniques in the proteome research of leukemia cells .

结论蛋白质芯片技术是发现与筛选VSD血清标志蛋白的快速、有效的蛋白质组学工具。

Conclusion ProteinChip technology is a quick and effective tool of proteomics , and it is capable of discovering and screening serum protein markers of VSD .

蛋白质组学分析表明，IUGR减少与肌肉剪切力相关的肌球蛋白重链和肌钙蛋白表达量以及与能量代谢相关的丙酮酸激酶和磷酸甘油变位酶表达量（P0.05）。

Proteomic analysis indicated that IUGR decreased the expression abundances of shear force-related myosin heavy chain and troponin T , and energy metabolism-related pyruvate kinase and phosphoglycerate mutase ( P0.05 ) .

驱除侵袭大质粒pINV对福氏2a志贺氏杆菌2457T影响的比较蛋白质组学研究

Comparative proteomics research on removing of large invasive plasmid pINV of Shigella flexneri 2a strain 2457T

详细比较了5种染色方法的效果，B2法无酸性端歧视效应，脱色速度快，与质谱兼容，在功能蛋白质组学研究中有应用前景。

In 5 staining methods , method B2 has the advantage of dyeing acid end of strip , faster destaining and it is suitable for mass spectrometry detection .