心脏毒
- 【药】cardiotoxic
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Fura-2荧光测定实验显示,眼镜蛇心脏毒(CTX)能明显升高新鲜分离的大鼠心肌细胞的胞浆Ca2+浓度。
In this study , the fura-2 fluorescent technique was used to determine the effects of Ca2 + entry blockers on the increase of cytoplasmic free Ca2 + concentration induced by cardiotoxin ( CTX ) in freshly isolated rat heart cells .
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眼镜蛇心脏毒一级结构和功能关系的定量分析
Quantitative analysis of the primary structure-function relation of cardiotoxin from cobra venom
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吸入一氧化氮对大鼠心脏毒副作用的影响
Toxic and side effects of nitric oxide on the heart of rats
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肝素的异质性以及可被调控的肝素结合模式将可决定心脏毒蛋白的组织辨识特异性及其生物意义。
The heterogeneity of heparin and regulated heparin binding mode might determine different tissue specificity for different CTX homologues and their biological significance .
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钙流拮抗药对眼镜蛇心脏毒升高大鼠心肌胞浆Ca~(2+)作用的影响
Effects of Ca  ̄( 2 + ) entry blockers on the increase of cytoplasmic free Ca  ̄( 2 + ) by cardiotoxin in rat heart cells
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大气PM(2.5)对自发性高血压大鼠心脏的急性毒作用
Study on Acute Toxic Effects of PM_ ( 2.5 ) on Heart in Spontaneous Hypertension Rats
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但是该类药物累积心脏毒性等多种毒副作用限制了其治疗作用,因此降低毒副作用而保留其抗肿瘤活性一直是这类化合物研究开发的热点。
But these drugs cumulative cardiac toxicity and other side effects limit its efficacy . The development of reduced toxicity while retaining its antitumor activity has been the research focus of this class of compounds .